Hutch News
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Struggle between sex chromosomes underlies evolutionary paradox
DNA-packaging protamine genes evolve rapidly to stay ahead in battle between ‘selfish’ genetic elements and the rest of the genome
New computational tools widen horizons for liquid biopsies
Methods allow scientists to use gene regulation patterns to detect cancer subtype in cell-free DNA
Multi-Ancestry Polygenic Risk Scores (PRS) of prostate cancer: A meta-analysis
From the Darst Group, Public Health Sciences Division
Micro-RNA in weight loss and breast cancer
From the McTiernan Group, Public Health Division
Peeling back the layers of a cell’s epigenomic data
From the Henikoff and Setty labs, Basic Sciences and Public Health Sciences Divisions
Drs. Harmit Malik and Steve Henikoff elected to American Academy of Arts and Sciences
Election honors scientists’ contributions to understanding of fundamental biology
Hopes and predictions for 2022
Hutch researchers look ahead to an increase in cancer screening, improved vaccines and greater trust in science
Epigenetic heterogeneity helps cancer cells change their minds
From the Henikoff Lab, Basic Sciences Division and the Meshinchi Lab, Clinical Research Division
You’ve got something in your eye: cellular reprogramming in development and cancer
From the Henikoff Lab, Basic Sciences Division
Holding the line: low CpG content and DNA inaccessibility safeguard T cell commitment
From the Bernstein Lab, Clinical Research Division
Omics made easier
To see the big picture, just add ‘ome’
Fundamental proteins that guide embryo development are co-opted by cancer
Researchers discover why some critical DNA-packaging proteins called histones evolve rapidly — and may give cancer a boost
Tip Sheet: COVID-19 vaccines, SARS-CoV-2 mutations, shedding pandemic pounds – and nematode nerve cells
Summaries of recent Fred Hutch research findings and other news
Could bacterial enzymes drive cancer formation by directly modifying human DNA?
W.M. Keck Foundation grant will help scientists pioneer new technologies to find out
New method quickly, precisely maps epigenome in single cells
CUT&Tag speeds process of precisely locating molecules that turn genes on or off
Understanding the genetics of X chromosome inactivation
from the Bedalov lab, Clinical Research Division
Parsing the deadliness of prostate cancer
Fred Hutch researcher zeroes in on biomarkers to better predict aggressive form of the disease
An island of bladder cancer susceptibility
From the Bhatti Group, Public Health Sciences Division
‘Waistbands’ of our chromosomes marked by unusual X-shaped DNA
Human Y chromosome’s center more ‘monkey-like’ than other human chromosomes, study finds