Human Biology Division - Fred Hutchinson Cancer Research Center

Human Biology Division

Image: Human Biology laboratory

Integrating fundamental, applied and translational scientists to improve the diagnosis, treatment and prevention of cancer and other diseases.

Human Biology researchers come together to form a multidisciplinary team that is influenced by individual advances. Their diverse expertise include molecular and cell biology, genomics, genetics, virology, infectious disease, computational biology, pathology and clinical research. Grounded in high-quality basic science, the research performed in Human Biology blends fundamental, applied, and translational research performed in model organisms and in vitro systems.


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Congratulations to our Senior Operations Director, Raquel Sanchez, for being awarded one of Puget Sound Business Journal's 40 under 40.
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Dr. Denise Galloway was awarded one of the National Cancer Institute’s 2017 Outstanding Investigators Awards. This award recognizes scientific leaders who are making significant advances in research. Galloway is also the first scientist from Fred Hutch to receive this award.
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Together Fred Hutch, UW Medicine and SCCA are working to develop the most precise treatment options for patients with solid tumor cancers. The primary goal is to translate laboratory sciences into the most precise treatment options for patients with solid tumor cancers.
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Helicobacter pylori (H.pylori) is a common bacterium that causes an infection in the stomach and in some cases can lead to ulcers and cancer. The Salama Lab has identified a second factor that contributes to the inflammatory response after the body has detected an infection.
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We will be welcoming our newest junior faculty member, Dr. Daphne Avgousti, later this year. Dr. Avgousti’s lab will focus on the mechanisms by which viruses hijack chromatin. Her goal is to advance the basic understanding of viral manipulation of chromatin and uncover new aspects of chromatin biology.
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The Clurman Lab is interested in transitions into and out of the DNA replication stage of the cell cycle, S-phase. Ryan Davis, a graduate student in the Clurman Lab, found that the phosphatase PP2A-B56 plays a part in prolonging the lifetime of the S-phase associated Cyclin E. This study has uncovered new aspects of the Cyclin E regulation by this phosphatase and implicated it as a possible oncogene.
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New junior faculty member, Dr. Alice Berger, was awarded the President’s Young Investigator Award amounting in a grant worth $100,000 for “unrestricted” research.
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Dr. Patrick Paddison and collaborators at Mount Sinai Medical School propose that the sensitivity of GBM tumor cells to inhibition of BUB1B, a molecule involved in the checkpoint before cell division, may be an effective predictive marker of tumor aggressiveness and responsiveness to specific treatments.
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Dr. Slobodan Beronja and colleagues from Yale University demonstrated that healthy skin cells have the ability to fight off the cancerous tendencies of nearby cells. When skin cells containing oncogenic mutations begin forming disordered growths, neighboring normal skin cells surround the deformed tissue and either push out the growths or convert them into functional skin structures.
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Dr. Denise Galloway will be the Director of the Pathogen-Associated Malignancies Integrated Research Center. The goal is to bring together Hutch experts to better understand, treat and prevent cancers linked to infectious agents.
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Faculty & Labs

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