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9 Found open positions

Post-Doctoral Research Fellow

FH Human Biology Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 21769

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 

The Bullman Laboratory is an interdisciplinary and highly collaborative team of clinical microbiologists, computational biologists, biochemists and cancer geneticists. The core mission of our laboratory is to improve diagnosis and treatment of human cancer to ultimately extend the lives of cancer patients, with a particular focus on gastrointestinal cancers. Using cutting edge technologies and methodologies, we endeavor to move smoothly between large human data sets and in vivo and in vitro model systems to gain a deeper functional understanding of the tumor microbiota in cancer progression, metastasis and response to treatment

Responsibilities

The Bullman Laboratory in the Human Biology Division at the Fred Hutchinson Cancer Research Center is recruiting a highly motivated Postdoctoral Fellow with expertise in murine models of cancer and mammalian cell biology to join our tumor microbiome efforts. An interest in microbiome research is required but hands on experience is not required as ample training can be provided.

 

Our goal is to understand the interaction of the colon cancer microbiota with the tumor microenvironment. This individual will utilize state-of-the-art spatial imaging technologies, single cell sequencing in addition to genomics and informatics techniques in a highly collaborative, stimulating, and collegial research environment. This position will provide opportunities for professional development and the acquisition of cutting-edge skills in single cell sequencing, small molecule screens, analysis of clinical specimens, tissue imaging approaches, host-microbiome interactions, research planning and strategy, and data analysis and interpretation.

Qualifications

  • PhD in biological sciences, cancer biology, computational biology, pathology, microbiology, or a related field
  • A record of scientific accomplishment as shown by peer-reviewed publication
  • A collaborative, curious, creative, proactive and organized temperament
  • A commitment to advancing fundamental knowledge of the cancer microbiome and to translating that knowledge to the development of novel therapeutic approaches

 

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment. 

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Post-Doctoral Research Fellow - Targeted Protein Degradation – Nabet lab

FH Human Biology Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 20699

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.


 

Dr. Behnam Nabet’s laboratory is recruiting a highly motivated postdoctoral fellow to carry out research in the fields of targeted protein degradation and proximity-induced therapeutics. The goals of our research program are to develop strategies to target cancer drivers by controlling protein homeostasis to gain new biological insights into clinically relevant targets and to advance new therapeutic strategies in cancer. The Nabet lab develops and deploys innovative chemical biology technologies such as the dTAG system to rapidly eliminate target proteins for therapeutic target discovery and validation (Nabet et al., Nature Chemical Biology 2018, Ferguson and Nabet et al., Nature Chemical Biology 2020, Nabet et al., Nature Communications 2020). We are committed to supporting the next-generation of scientists and believe in collaborative science (Nabet, ChemBioChem 2021). This is an exceptional opportunity to join a new team with a committed mentor that is pushing the boundaries of cancer chemical biology.

Responsibilities

The successful applicant will drive rigorous scientific projects utilizing state-of-the-art targeted degradation approaches including the dTAG system, chemical probes, genome-wide CRISPR knockout screens, molecular biology, biochemistry, next-generation sequencing, and in vivo murine modeling, with the goal of understanding the mechanisms of oncogenes in cancer and developing new therapeutic approaches. The position will require both independent research as well as the ability to collaborate closely with medicinal chemists, computational biologists, and other colleagues.

Qualifications

Essential skills and requirements

We are looking for exceptional candidates with a recent PhD, and/or MD and a track record of independent productive research. Excellent written and verbal communication skills are required. A strong foundation in cell culture, genetic engineering, next-generation sequencing, murine modeling, molecular biology, biochemistry, and/or chemical biology is highly desirable. Fellowship opportunities are available through several philanthropic and government organizations and recruits who join the lab will be supported in their applications.

 

Application instructions

Please apply by submitting a CV, a brief description of past research experiences and future goals (not more than 1-2 pages) and contact information for three references.

 

 

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment. 

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Post-Doctoral Research Fellow, mRNA Translation in Cancer

FH Human Biology Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 18969

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.


At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

 



A postdoctoral position is immediately available in the Hsieh Lab at the Fred Hutchinson Cancer Center. The core focus of the Hsieh Lab is to interrogate the mechanisms by which post-transcriptional gene regulation governs cancer cell behavior at a molecular, cellular, and organismal level (Hsieh et al. Nature 2012, Schuster and Hsieh Trends in Cancer 2019, Winters et al. JCI Insight 2019, and Liu et al. Science Translational Medicine).

Responsibilities

For this position, the applicant will utilize murine genetics, whole transcriptome ribosome profiling, functional genomics, RNA labeling/sequencing techniques, various cellular and molecular assays, and a one-of-a-kind biorepository of primary and metastatic human prostate and bladder cancer samples to understand how the translation apparatus promotes cancer phenotypes.

 

Fred Hutch has more than 200 postdoctoral fellows working in labs across all five research divisions. We provide postdocs with the opportunity to work on the cutting edge of biomedical research in a supportive, collaborative environment with faculty and staff who are dedicated to helping their trainees achieve their career goals. In addition, both the Student/Postdoc Advisory Committee and the Office of Scientific Career Development offer diverse mentoring and career development opportunities.

Qualifications

Minimum qualifications
We are looking for exceptional candidates with a recent PhD and/or MD, a record of productive research, and the ability to work independently as well as in collaborative research efforts.


Preferred qualifications
A strong background in murine work, high throughput methods, RNA biology, and/or computational biology are highly desirable. Excellent verbal and written communication skills are required.

 

Application instructions:

To apply for this position, please provide the following:

  • Cover letter summarizing your research interest
  • CV
  • Contact information for three references

 

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment. 


A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Research Administration Manager I

FH Human Biology Division
Category: Research Administration & Faculty Affairs
Seattle, WA, US
Job ID: 22670

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research, and learning. The only National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease, and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 

The Research Administration Manager I (RAM I) will be responsible for the successful pre- and post-award management of grants and contracts of a multimillion-dollar program portfolio of the Prostate Cancer Program (PCP) in the Human Biology Division (HB). This position requires an understanding of federal regulatory requirements, human resources management, administrative systems, financial analysis, and team leadership. They ensure compliance with all sponsor rules and regulations. They ensure the accuracy of project budgets and contracts, reconcile expenditures throughout project life cycle, and track progress of awards from pre-award to project closeout.

 

A successful candidate in this role will be an enthusiastic learner who is ready to engage with a variety of systems and tools. They will be resourceful, patient with change, and comfortable with hybrid communication tools. They will be organized, responsive, and proactive about following up on tasks. They will have courage to ask questions and capacity to be flexible about the varying ways people approach work. They will be able to effectively engage with a broad range of roles within the organization. Finally, they will be an engaged team player, someone who can support and collaborate with peers around collective professional success and wellness.

Responsibilities

Budget/Fiscal Management

  • Provide ongoing cost oversight to ensure sponsored projects are adequately expensed
  • Participate in strategic planning activities such as setting goals and defining annual objectives
  • Develop, monitor, track, and project budgets for a complex portfolio of projects varying considerations (eg, multi-site, sub awards etc.)
  • Develop, run, and analyze reports aimed at oversight of over- and under- spending, compliance with sponsor regulations and forecasting future expenses
  • Funding Source Administration: lead pre- and post-award activities including:
    • Complete technical/non-scientific portions of submissions
    • Partner with faculty on sponsor communications
    • Prepare and review budgets, identify discrepancies and provide recommendations to PI on scenarios to resolve issues with appropriate stakeholders

 

Regulatory Oversight

  • Interface with faculty to develop, negotiate, and manage highly complex sponsored proposals, working to anticipate regulatory issues and ensure all submissions are amended to reflect current local, state, federal and sponsor regulations
  • Prepare, consult, and advise PIs on non-scientific portions of regulatory applications/submissions
  • Advise or consult with Center leadership on changes to Center-wide policies/procedures and help create implementation plans in response to changing regulatory requirements
  • Serve as a central point of contact to answer questions and facilitate solutions

 

Administrative Support

  • Identify administrative needs for PCP and participating PI(s); prioritize and ensure related tasks are completed
  • Identify space and resource shortages and develop recommendations to resolve related issues
  • Oversee management of projects including occasional event planning and management
  • Communicate with other departments/entities on PI’s behalf
  • Resolve discrepancies and issues with stakeholders on PI’s behalf
  • Track projects in startup, developing plans with parallel work-streams and clear timelines, communicating between stakeholders, and holding accountable the team members whose input is required
  • Coordinate project audits and close-outs
  • Perform other responsibilities as required

 

Leadership and Mentoring

  • Coach and train entry-level staff
  • Work with Center and HB Division Leadership to continuously identify operational issues and areas of improvement to ensure optimum conduct of research studies
  • Track PCP grants and provide summaries to HB leadership
  • Develop short- and long-term PCP goals to procure necessary resources for program administration
  • Supervise PCP Research Administration staff to include hiring, performance evaluation, professional development, handling disciplinary action, layoff, and termination issues
  • Participate in Divisional or institutional process improvement projects related to research administration

Qualifications

Minimum Qualifications:

  • Bachelor’s degree in Business Administration, Public Administration, or related field; an equivalent combination of education and experience may be substituted for minimum education requirement
  • Minimum of five years of experience in pre-award and post-award research administration or grants and contracts management, ideally managing Federal or State sponsored awards in a complex, multi-faceted portfolio
  • Experience with grant and contract regulatory agencies and reviewing IRB and IACUC documents
  • Ability to navigate complex internal systems and departments while exercising sound judgement and discretion
  • Proficient with complex budget development, including forecasting and use of various financial reporting tools
  • Excellent time management and prioritization skills
  • Excellent written and oral communication skills
  • Highly organized and detail-oriented, with the ability to problem-solve and process information quickly
  • Advanced skills in MS Word, MS Teams, MS Outlook, Adobe Acrobat Pro, Excel (ability to use pivot tables)
  • Demonstrated ability to work successfully as part of a diverse team with a commitment to equity and inclusion
  • A cover letter is required for this position
  • A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is required

 

Preferred Qualifications:

  • Master of Business Administration (MBA), Master of Public Administration, or equivalent
  • Experience managing NIH SPORE grants and contracts

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations. As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Research Techn I-II

FH Human Biology Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 22020

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 

The Tapscott Lab is composed of an interactive group of scientists investigating lineage specification and cell differentiation. The lab focuses on gene transcription in a chromatin context in normal development and disease. Areas of current interest include the regulation of early stem cell programs in development and cancers, including transcriptional and translational reprogramming, to identify the molecular bases of totipotency, pluripotency, specification, and differentiation. Findings from model developmental systems are applied to understand human diseases, including cancers and degenerative diseases.

 

Additional information about research in the Tapscott Lab can be found at:  https://research.fhcrc.org/tapscott/en.html

Responsibilities

Research Technician I-II will be responsible for performing standard and investigative laboratory work in support of scientific research by performing bench-level experiments, operating analytical instruments, recovering, compiling and verifying the accuracy of research data, performing calculations, and preparing charts, graphs and summaries. The lab uses standard molecular biology techniques and tissue culture.

 

Job Duties:

  • Perform experiments at the bench level to support investigative work
  • Prepare and maintain laboratory reagents, stocks, cultures or cell lines
  • Perform and modify documented protocols and assays
  • Maintain laboratory records and compile data on experiments and assays
  • Interpret and report on experimental results
  • Perform statistical analysis of test results and prepare written reports on work performed
  • Operate and carry out basic maintenance of laboratory equipment
  • Order and maintain appropriate levels of supplies
  • May supervise work-study students
  • Participate in lab meetings and journal clubs
  • Perform other duties as required

Qualifications

Research Technician I: 

  • BA/BS in a scientific field required
  • Must have scientific knowledge in the area of study and basic laboratory skills
  • Independent research experience in addition to school lab experience is required

Research Technician II:

  • Intermediate level position requiring 2 years previous experience working in a laboratory and BA/BS
  • A Master's degree can substitute for 2 years of post-graduation lab experience

A successful candidate will have scientific curiosity, a high level of self-motivation, the ability to take instruction and correction and to follow directions, good organizational skills and the ability to work and think independently. The candidate must have a track record of reliability and good verbal and written communication skills. This is an ideal position for a recent graduate who wants to gain an intense research experience before pursuing graduate school or for an individual looking for a long-term career as a research technician.

 

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Research Technician I

FH Human Biology Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 22856

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Responsibilities

There is an opening for a Research Technician I in a laboratory within the Human Biology Division for supporting the development, testing, and use of CRISPR-Cas9 gene editing libraries and technology in mammals. The position will use molecular, cellular, and functional genetic techniques on a daily basis with a significant focus in human stem cell biology. The position will contribute to establishing CRISPR-Cas9-based targeting systems at the Center.

Qualifications

  • BA/BS in a scientific field required.
  • Must have scientific knowledge in the area of study and basic laboratory skills. 
  • Independent research experience in addition to school lab experience is usually necessary.

 

Desired qualities and skills:

  • Highly motivated and intellectually curious.
  • A solid background knowledge in cell biology and/or cancer biology.
  • Excellent written and verbal skills.
  • Ability to maintain organized laboratory notebook and computer files.
  • Exceptional attention to detail.
  • Experience with murine research models.
  • Interested in long term laboratory management position.

 

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Research Technician I, Microbiota and Colorectal Cancer Research - Bullman Lab

FH Human Biology Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 22789

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 

The Bullman Laboratory is an interdisciplinary and highly collaborative team of clinical microbiologists, computational biologists, biochemists and cancer geneticists. The core mission of our laboratory is to improve diagnosis and treatment of human cancer to ultimately extend the lives of cancer patients, with a particular focus on gastrointestinal cancers. Using cutting edge technologies and methodologies, we endeavor to move smoothly between large human data sets and in vivo and in vitro model systems to gain a deeper functional understanding of the tumor microbiome in cancer progression, metastasis and response to treatment.

 

The Bullman Laboratory in the Human Biology Division at the Fred Hutchinson Cancer Research Center is recruiting a highly motivated Research Technician I with expertise in next-generation sequencing (NGS) technology (library preparation and associated analysis) and general microbiology (microbial culture/media preparation, nucleic acid isolation/manipulation) to join our tumor microbiome efforts. The position is intended to provide support for our day-to-day sequencing projects and ongoing microbial technology developments, as well as supporting general laboratory responsibilities.

Responsibilities

This individual will work with the PI and post-doctoral fellows using state-of-the-art sequencing technologies, small molecules screens, in addition to genomics and informatics techniques in a highly collaborative, stimulating, and collegial research environment. This position will provide ample opportunities for professional development and the acquisition of cutting-edge skills in single cell sequencing, small molecule screens, analysis of clinical specimens, tissue imaging approaches, research planning and strategy, and data analysis and interpretation.

 

Specific duties may include:

  • Anaerobic bacterial culture from clinical specimens
  • Adhere to standard operating procedures (SOPs) for isolation and analysis of DNA and RNA from patient tissue specimens and microbial cells.
  • Standard PCR and qPCR analysis
  • Maintenance and analysis of mammalian cancer cell line cultures
  • Conducts diligent record-keeping and reporting
  • Maintenance of general lab supplies, consumables and equipment
  • Ordering/cataloging of laboratories supplies and reagents
  • Presenting findings at internal (Bullman Lab) meetings
  • Other research or organizational duties, as appropriate.

Qualifications

MINIMUM QUALIFICATIONS:

  • Bachelor's degree in a biological science or related field with lab experience outside of coursework
  • Highly-motivated individual interested in a career in translational research, with a keen interest in sequencing-based technologies and tissue imaging
  • Technically meticulous when conducting experiments
  • Highly organized in record-keeping
  • Independent, intellectually passionate and able to display scientific initiative
  • Excellent teamwork, time management and organizational skills
  • Ability to work both independently and as part of a team in a dynamic and results-oriented environment
  • Ability to meet deadlines and multitask efficiently is a must

PREFERRED QUALIFICATIONS:

  • Basic molecular biology and microbiology techniques, such as bacterial isolation and culture, mammalian cell culture, DNA/RNA/protein extraction and qPCR is highly desirable.
  • A working knowledge and previous experience in next generation sequencing technologies is highly beneficial to the role.
  • Previous hands-on experience with in-situ hybridization or fluorescent imaging techniques is a benefit.
  • Experience in scientific programming/scripting for analysis of DNA/RNA sequencing data is a plus but not required.

Please include a cover letter with your application, detailing your interest and suitability for this position.

 

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment. 

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Research Technician I-II, Beronja Lab

FH Human Biology Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 22313

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   


 

A Research Technician I or II position (full-time) is immediately available in the Beronja Lab in the Human Biology Division at Fred Hutch. We are looking for a motivated, bright, and meticulous individual to contribute to a research program centered on identifying cellular and molecular mechanisms of stem cell regulation and tumorigenesis.

 

The ideal candidate will have a strong interest in stem cell biology, immunology, mouse modeling and application of cutting edge technologies. The technician will be responsible for performing standard and investigative laboratory work, including, following detailed, time-sensitive and challenging protocols to generate mouse models and cell/tissue transplant experiments, conducting flow-based immunologic phenotyping experiments, conducting and quantifying tumor measurements by a variety of in vivo and ex vivo imaging approaches, and by conducting and quantifying tissue-based immunofluorescence.

Responsibilities

The successful candidate will work alongside the Principal Investigator and with other lab personnel to:

  • Generate expression plasmids and produce lentivirus
  • Perform experiments that include basic molecular and biochemical bench-work, cell culture of mouse and human cells
  • Perform ultrasound-guided microsurgeries on mice
  • Conduct immunostaining of tissues, confocal imaging of tissue sections and intravital imaging of intact skin
  • Perform flow-based immune cell phenotyping experiments
  • Conduct literature reviews, data analyses and presentation
  • Keep detailed and meticulous records.
  • Perform other duties as required

As you become familiar with every aspect of the lab activities, you will take on a role in training and supervision of new lab members.

Qualifications

  • A B.Sc. in biology or a related field is required.
  • Strong organizational skills and work ethic, eagerness to learn, and a passion for science are essential.
  • Candidates with at least one-year (RT I) or more (RT II) of independent research experience in a laboratory setting in cell biology, immunology, or related disciplines are encouraged to apply.

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment.

 

For consideration, please apply with a resume, a completed application, and the names and contact info of three professional references.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

Research Technician II

FH Human Biology Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 22715

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit, unified adult cancer care and research center that is clinically integrated with UW Medicine, a world leader in clinical care, research and learning. The first National Cancer Institute-designated cancer center in the Pacific Northwest, Fred Hutch’s global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy, and COVID-19 vaccines has confirmed our reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Based in Seattle, Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy, and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures for the world’s deadliest diseases and make life beyond cancer a reality.

 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

 

The Research Technician II position will be in a lab that works in multiple disciplines to address the molecular basis of brain tumors and developing new approaches to their treatment. The research focuses on developing murine models of brain cancer that mimic the behavior of the disease in patients, using a system of postnatal gene transfer to study brain cancer formation in developed murine models, providing a model for the development of gliomas and medulloblastomas.

Responsibilities

We are seeking an experienced Research Technician to assist in management of drug studies, support various ongoing projects, and maintain murine colonies in a laboratory within our Human Biology Division. Other responsibilities include:

  • Prepare and maintain reagents, stocks, and cultures necessary to perform the work
  • Maintain and perform husbandry and genotyping of murine colonies, as well as, to maintain associated databases
  • Histology, cell culture, maintain mice colonies, imaging mice, stocking reagents
  • Tag, weigh and record data used for tracking purposes and administer drugs/reagents per guided protocols, including the harvest of brain tumors
  • Perform, collect and analyze flow cytometric assays
  • Maintain records for experiments and quality control for the laboratory
  • Maintain a high level of accuracy for all work
  • Work well as team-member
  • Operate and carry out basic maintenance, cleaning and stocking of lab supplies and equipment
  • Perform other duties as assigned
  • Must be able to work weekends

Qualifications

  • A Bachelor's degree is required
  • At least two years of research experience with cloning, imaging and histology techniques, as well as in developing murine tumor models, and the associated techniques related to murine husbandry and maintenance is required
  • Demonstrated experience with working independently and in developing and optimizing various assays is also required

 

Fred Hutch has a mandatory COVID-19 vaccine requirement, with exceptions only for approved medical or religious accommodations.
As a condition of employment, newly hired employees must provide proof of vaccination or initiate the accommodations process before their first day of employment.

 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

 

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