Human Biology Job Openings

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Kugel Laboratory is accepting applications for a Lab Technician position. The laboratory uses basic and translational research approaches to explore pathogenic mechanisms and novel targeted therapies in pancreas and biliary cancer. Successful candidates will learn to generate and exploit a series of fundamental cancer model systems including genetically engineered murine models (GEMMs), patient-derived xenografts and novel human cancer cell lines.

Responsibilities

The incumbent will have the opportunity to become involved with all the steps of research being completed by the group and contribute to publications, with the ultimate goal of translating their findings into novel clinical trials for pancreas and biliary cancer patients. Scientific methodologies and areas of focus include animal models and murine genetics, molecular biology, cell biology and metabolism, proteomics, biochemistry, pharmacology, and genomics. The experience gained in the lab will be useful for pursuing a career as a researcher or physician. 

Qualifications

MINIMUM QUALIFICATIONS:

• One (1) year of college coursework emphasizing laboratory science or equivalent, or one year experience as a Laboratory Tech I or equivalent.

PREFERRED QUALIFICATIONS:

• Bachelors's degree in biochemistry, molecular biology or related field.
• Experience with mammalian cell culture and murine models.
• Must be comfortable handling mice. 
• Priority will be given to candidates who can make a 2-year commitment to the role.
• Detail-oriented, organized, and able to work independently as well as part of a team in a challenging environment.
• Excellent communication and organizational skills.

The hourly pay range for this position is from $22.87 to $32.56 and pay offered will be based on experience and qualifications.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). 

Additional Information

The Fred Hutchinson Cancer Center (Fred Hutch) is recruiting a faculty member at the rank of Associate Professor or Full Professor to lead/direct the prostate cancer program (PCP), one of nine programs that comprise the NCI-supported Cancer Consortium which includes the Fred Hutch, University of Washington and Seattle Children’s Hospital. The faculty member will have a primary academic appointment in one of the seven Fred Hutch Scientific Divisions. In addition to leading the PCP, the scientist and/or physician will be expected to maintain a vibrant independent research program focused on prostate cancer. This position will be a full-time, multi-year appointment.

We will consider PhD, MD/PhD, or MD scientists and physicians working in areas that include, but are not limited to: primary prevention, etiology, genetics/genomics, epigenetics, tumor microenvironment, metastasis, development of novel therapeutics, therapeutic resistance, biomarkers, DNA damage response, steroid receptors, immunotherapy/immunology, systems-biology, and/or computational-biology. Applicants should embrace a role in establishing a program vision that encompasses diverse faculty interests, maintains and enhances a highly collaborative research environment, leverages a robust infrastructure and orientation toward translational science, and develops the careers of junior faculty. A track record of leadership, relevant impactful publications, and funding commensurate with appointment level is highly desirable.

The successful candidate will enter a dynamic and highly collaborative research environment as a member of the Prostate Cancer Program and will benefit from the infrastructure and resources available through the Pacific Northwest Prostate Cancer SPORE and the Institute for Prostate Cancer Research. They will have opportunities to collaborate with scientists across a wide array of disciplines. Collaborations may be enhanced via joint and/or affiliate appointments at the University of Washington, depending upon mutual interests.

Faculty are expected to perform their primary activities on-site at Fred Hutch. 

Fred Hutch is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington State. Additional information about Fred Hutch and the Scientific Divisions can be found at: https://www.fredhutch.org/en/research/research-areas.html

With a track record of global leadership in prostate cancer research, bone marrow transplantation, HIV/AIDS prevention, immunotherapy, COVID-19 vaccines and other research areas, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

Anticipated Start Date: 2025

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Kugel Laboratory is seeking a highly motivated Post-Doctoral Research Fellow interested in exploring how the dysregulation of chromatin modifying enzymes and developmental pathways contribute to pancreas and biliary cancer pathogenesis and, further, whether these pathways present liabilities that can be exploited for cancer therapy.

Responsibilities

Successful candidates will learn to generate and exploit a series of cancer model systems including genetically engineered murine models (GEMMs), patient-derived xenografts and novel human cancer cell lines to understand fundamental pathogenic mechanisms underlying pancreatic cancer. To answer these questions the laboratory uses state-of-the-art techniques in murine models and genetics, molecular biology, cell biology, biochemistry, metabolism, RNA profiling, proteomics, pharmacology, genomics and computational biology.

Qualifications

MINIMUM QUALIFICATIONS:

• Qualified applicants will have recently obtained a PhD and/or MD or be nearing completion of their graduate studies and have an interest in cancer research.
• Proficiency in written and verbal English is required.

PREFERRED QUALIFICATIONS:

• A track record of productive research is strongly preferred.
• Applicants with specific expertise in RNA biology, biochemistry, cell biology, cancer genomics, murine models or computational biology are highly encouraged to apply.
• Fellowship opportunities are available through several philanthropic and government organizations; and recruits who join the lab will be supported in their applications.

Please apply by submitting a CV, a brief description of past research experiences and future goals (not more than 1-2 pages) and contact information for three references.

The annual base salary range for this position is from $77,976 to $95,014.40 and pay offered will be based on experience and qualifications.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

A Post-Doctoral Research Fellow position is available in the lab of David MacPherson at Fred Hutch which is focused on the biology of small cell lung cancer (SCLC). We apply functional screens and analyses of genetically engineered mouse (GEM) and patient derived xenograft (PDX) models towards understanding genes mutated in SCLC and basis of response and resistance towards conventional and novel therapies. Projects use cutting edge genomics and CRISPR screening approaches and we work closely with thoracic oncologist collaborators at Fred Hutch to help translate basic findings to the clinic. Some of these directions are supported by an NIH Lung Cancer SPORE award that promotes translational lung cancer research. 

Responsibilities

The specific project will be developed by both the candidate and Dr. MacPherson based on areas of shared interests.  Major areas of current interest include 1) understanding response and resistance to therapy using a combination of functional screens, in vivo modeling and genomic analyses of patient samples 2) developing innovative liquid biopsy assays and 3) modeling biologically distinct subsets of SCLC using mouse and PDX systems.  Projects are typically multidisciplinary and can involve co-mentorship where appropriate.  The position will require both independent research as well as the ability to collaborate closely with colleagues.

Other Expectations

• Work collaboratively within the MacPherson Lab and with Fred Hutch and external collaborators.
• Apply for postdoctoral fellowships and/or career development awards.
• Deeply engage with their scientific problem and drive project direction.

Qualifications

• Recent PhD in Biology or related fields
• Excellent oral and written communication skills
• Must be able to design and execute experiments, interpret data and present results
• A record of publication in peer reviewed journals, with at least one lead author publication

The annual base salary range for this position is from $77,976 to $95,014.40 and pay offered will be based on experience and qualifications. This position may be eligible for relocation assistance.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. 

Are you interested in joining a lab focused on cutting-edge CRISPR screening and immuno-oncology? The Li Lab at Fred Hutchinson Cancer Center (https://research.fredhutch.org/haolong-li/en.html) is seeking highly motivated and collaborative postdoctoral fellows to join our dynamic team. We are dedicated to advancing cancer research and developing new treatments. Our research integrates functional and clinical genomics to uncover molecular mechanisms driving cancer treatment resistance and accelerate the development of novel therapies. We employ state-of-the-art techniques such as CRISPR screening, next-generation sequencing, and in vivo mouse modeling, with a focus on prostate cancer as a model system. Our lab is part of the Prostate Cancer Program and is located next to the Nelson Lab (https://research.fredhutch.org/peternelson/en.html) and the Haffner lab (https://research.fredhutch.org/haffner/en.html). Postdocs will have opportunities for collaboration and co-mentored with PIs in the program.

Postdoctoral fellows will lead independent research projects with direct translational relevance to cancer treatment. We’ve already established cutting-edge platforms and collected exciting data ready to be explored. Successful candidates will have the chance to lead and be first authors on projects aimed at identifying novel therapeutic targets and developing new combination treatment strategies.

Responsibilities

• Design and execute independent research projects under the mentorship of Dr. Li.
• Apply for independent funding (intramural and extramural).
• Participate in grant writing, manuscript preparation, lab meetings, and journal clubs.
• Mentor junior lab members, including technicians and students.
• Contribute to and lead publications in high-impact journals.

Qualifications

MINIMUM QUALIFICATIONS:

• PhD (or equivalent) in cancer biology, molecular biology, tumor immunology, or a related field.
• Strong written and oral communication skills.
• Self-motivated, collaborative, and enthusiastic about cancer research.
• Ability to work independently and as part of a team.

 PREFERRED QUALIFICATIONS:

• Background in cancer immunotherapy research.
• Experience with large-scale omics data analysis and programming (R or Python).
• Proven track record of high-quality publications.
• Experience with molecular biology techniques (e.g., cell culture, CRISPR, NGS, immunohistochemistry,).
• Independent postdoctoral research funding is a plus.

We will consider applicants from diverse backgrounds and with different levels of experience. We will also base our evaluation on your specific interest and motivation for this position. Accordingly, in your application please include a cover letter that describes your interest and motivation related to the research area in our lab along with your CV and contact information for at least two references.

The annual base salary range for this position is from $77,976 to $95,014.40 and pay offered will be based on experience and qualifications.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Srivastava Lab at Fred Hutch is looking for a highly motivated Research Technician I to support the development of CAR-T cell immunotherapy for cancer. The successful candidate will assist with design, execution, and analysis of pre-clinical studies using murine tumor models to study strategies for improving CAR-T cell therapy. She/he should be capable of handling mice, maintaining detailed laboratory records, analyzing data, and reporting experimental results in a fast-paced environment. Responsibilities will include working both independently and as a member of a team, providing technical assistance with ongoing research projects.

Responsibilities

Primary Duties and Responsibilities

• Perform sterile tissue culture techniques, including primary T cell culture, growing and titering of retrovirus and lentivirus, and transduction of murine cells with retroviral/lentiviral vectors
• Assist with in vivo murine tumor model experiments, including: monitoring weight, body condition score, and tumor growth; administering injections (intravenous, intraperitoneal, and subcutaneous)
• Dissect and process various tissues, including spleen, peripheral lymph nodes, bone marrow, lungs, and tumors
• Analyze cell phenotype and function from in vitro and in vivo experiments using multi-parameter flow cytometry
• Prepare samples for analysis by next-generation sequencing methods, including single-cell RNAseq and CUT&Tag
• Molecular biology techniques, including bacterial plasmid preps, PCR, and cloning
• Maintain detailed records, schedule mouse studies and analyze data
• Provide basic support to the laboratory
• Perform general lab/equipment maintenance, keep stock of lab supplies, and assist the lab manager with general upkeep of the lab
• Computer skills: Microsoft Excel, PowerPoint, Prism (Graphpad), FlowJo

Qualifications

MINIMUM QUALIFICATIONS:

• Bachelor of Science degree in a biological science
• Prior experience working in a wet lab environment
• Detail-oriented, well-organized, and have good attention to detail
• Ability to communicate effectively and keep accurate records of work performed
• Ability to work on a team
• High level of self-motivation and initiative

PREFERRED QUALIFICATIONS:

• Prior experience with sterile tissue culture and mouse handling
• Prior exposure to immunology (this can be from coursework or prior lab experience.)

The hourly pay range for this position is from $22.87 to $32.56 and pay offered will be based on experience and qualifications.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). 

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

A Staff Scientist position is available in the MacPherson lab, which is focused on the biology of small cell lung cancer (SCLC). We apply functional screens and analyses of genetically engineered murine and patient-derived xenograft (PDX) models toward understanding genes mutated in SCLC and developing novel therapeutic approaches. Our group is also interested in understanding how to augment immune responses in SCLC and in developing new diagnostic approaches towards phenotyping lung cancer using liquid biopsies. The Staff Scientist would help advance translational research in the lab by working on both independent and collaborative projects. The candidate may contribute to a translational NIH Lung SPORE grant, including study of patient samples and derived models.

Responsibilities

• Perform independent research and contribute as a part of a team in various projects as needed
• Conduct therapeutic studies using murine models and perform molecular and genomic analyses to understand treatment responses
• There is potential to mentor trainees
• Present results in group meetings and prepare data for publication

Qualifications

MINIMUM QUALIFICATIONS:

• PhD in biochemistry, molecular biology, biology, genetics, or related field and 2+ years of postdoctoral experience
• Proficiency with molecular biology/biochemistry and/or genomics
• Excellent oral and written communication skills
• Must be able to design and execute experiments, interpret data and present results
• Must have a record of publication in peer-reviewed journals

PREFERRED QUALIFICATIONS:

• Experience with mouse models

The annual base salary range for this position is from $82,123 to $185,000 and pay offered will be based on experience and qualifications. This position may be eligible for relocation assistance.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (up to 13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 12 months for professor track faculty, up to 6 months for other scientific staff). 

Additional Information