Paul Lampe, Ph.D.

faculty member

Paul Lampe, Ph.D.

Head, Translational Research Program
Fred Hutch

Member
Public Health Sciences Division, Fred Hutch

Member
Human Biology Division, Fred Hutch

Fax: 206.667.2537
Mailstop: M5-C800

Dr. Paul Lampe is head of the Translational Research Program at Fred Hutch. The overarching goal of this program is to discover and translate molecular and epidemiologic findings to advance our understanding of the biological basis for various exposure-biomarker-disease relationships. Accomplishing this goal will improve precision prevention and interception, risk assessment, early detection, treatment decision making, prognostication and survivorship. Dr. Lampe’s research focuses on the discovery of molecules called biomarkers that can be used for the early detection of colon, breast, lung and pancreatic cancers. He also studies the cell biology of cancer and its development, particularly communication gateways between cells called gap junctions. When functioning properly, gap junctions relay molecular messages that help control key biological activities. Examples include coordinating the rhythmic contraction of the heart muscle and regulating normal cell growth. Dr. Lampe and colleagues discovered that when gap junctions are absent or damaged, serious health consequences, including cancer, can result.

Other Appointments & Affiliations

Research Professor, Global Health
University of Washington School of Public Health and Community Medicine

Education

Ph.D., Biochemistry, University of Minnesota, 1984

Current Projects

Discovery of Cancer Biomarkers via Proteomics

The Functional Consequences of Gap Junctional Regulation

Find A Clinical Trial

Dr. Lampe in the News

Early detection of colon cancer (feces-free version)

Science Spotlight - December 19, 2016

STK4: A potential novel biomarker for pancreas cancer

Science Spotlight - November 16, 2014

Dermcidin: a novel biomarker in breast cancer

Science Spotlight - April 21, 2014

Phosphorylating communication

Science Spotlight - January 20, 2014

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with faculty.

Email media@fredhutch.org or call 206.667.2210