Sickle cell disease affects each person differently. Some people have mild symptoms, while others experience frequent pain episodes or serious complications. Symptoms can change over time, making ongoing care from specialists experienced in sickle cell disease important.
Because sickle cell disease affects red blood cells and blood flow, it can impact many parts of the body. Understanding the symptoms and recognizing potential complications can help you know when to seek medical care.
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Common Symptoms
Symptoms of sickle cell disease vary from person to person and may change over time. Common symptoms of sickle cell disease include:
- Anemia
- Fatigue
- Pain episodes (also called pain crises or vaso-occlusive crisis)
- Shortness of breath
- Dizziness or lightheadedness
- Fast heart rate
- Pale skin
- Jaundice (when skin and the whites of eyes turn yellow)
Pain episodes are the most common symptom of sickle cell disease. They occur when sickled red blood cells block blood flow, reducing oxygen delivery to tissues and organs. Pain can range from mild to severe and may last for varying lengths of time.
If you have any recurring symptoms of sickle cell disease, let your primary care provider know. UW Medicine Primary Care can help you get started. Learn about Fred Hutch's relationship with UW Medicine.
Complications of Sickle Cell Disease
Over time, sickle cell disease can affect nearly every organ in the body. Some complications develop suddenly, while others occur gradually.
Your care team at Fred Hutch Cancer Center works to help prevent complications whenever possible and to recognize and manage them early.