Multiple myeloma has more than five dozen mutations with variable drug responses, making it extremely difficult to treat. Fred Hutch researchers have shown that it’s possible to quickly test patients’ tumor cells against more than 150 drugs in the lab to determine which will be most effective.
Our researchers have identified duplicate genes — which typically aid cancer by providing a backup if one gene dies — as a potential target for cancer drugs in patients with lung cancer.
Fred Hutch researchers have shown that some prostate cancer cells have high levels of a specific protein marker and using this marker to guide chemotherapy to these cancer cells could be an effective treatment.
We are much closer to understanding why some patients with a precancerous condition called Barrett’s esophagus progress to esophageal cancer, opening the possibility of future screening options that could identify who should be treated and who can just be monitored.