Who We Are

CITN and ION History

The Cancer Immunotherapy Trials Network (CITN) originated from workshops that occurred during a 2007 meeting of the world’s leading immunotherapy experts from academia, industry and government. The National Cancer Institute and the Fred Hutchinson Cancer Research Center together support CITN’s work.

Today, CITN and now ION, an affiliate of the CITN, comprises a network of top academic immunologists, clinical trial sites, laboratories and funding partners. The network’s investigators  are located at 40+ of the foremost universities and cancer centers in North America. A pioneer in immunotherapy research, Fred Hutch houses two critical components of CITN and ION: the Central Operations and Statistical Center (COSC) and the CITN and ION Immune Monitoring Lab (CIML).

research technician pipetting

Our Aims

Our Aims

The CITN and ION investigators are internationally-renowned cancer immunology experts as well as skilled clinicians. They have decades of experience spearheading innovative multi-center clinical trials to test therapies for complex diseases like cancer and HIV.

close up of scientist int he lab

Leadership

Leadership

The CITN and ION investigators are internationally-renowned cancer immunology experts as well as skilled clinicians. They have decades of experience spearheading innovative multicenter clinical trials to test therapies for complex diseases like cancer and HIV.

Meet Our Steering Committees

To help establish priorities for CITN and ION, the leaders work with two steering committees. The steering committees’ responsibilities include the following:

  • Develop and provide preliminary approval of Letter of Intent and protocols (before submission to NCI and final NCI approval)
  • Review trial progress
  • Review CITN Operations & Statistical Center (COSC) operations on a regular basis
  • Review any changes in CITN organizational structure
  • Review any changes in CITN Standard Operating Procedures (SOPs)
  • Advise on including Ancillary Sites to participate in CITN clinical trials

Adult CITN Steering Committee

Thomas Uldrick

Thomas S. Uldrick Jr., M.D., M.S.

Program Leader, Global Oncology and CITN/ION
CITN Co-PI, Cancer Immunotherapy Trials Network, Fred Hutch
Senior Clinician, HIV and AIDS Malignancy Branch
Deputy Chair, Global Health, Fred Hutch

Jeffrey Miller, M.D.

CITN Site Principal Investigator

Specialty: leukemia
Masonic Cancer Center
University of Minnesota, Minneapolis, MN

Marc Ernstoff, M.D.

CITN Site Principal Investigator

Specialty: kidney cancer, melanoma
Roswell Park Cancer Institute
Jacobs School of Medicine and Biomedical Sciences, UB, Buffalo, NY

Robert Ferris, M.D., Ph.D.

CITN Site Principal Investigator

Specialty: HPV in head & neck cancers
Department of Immunology
University of Pittsburgh, Pittsburgh, PA

Silvia Formenti, M.D.

CITN Site Principal Investigator

Specialty: breast cancer
Weill Cornell Medicine, New York, NY

Brian Gastman, M.D.

CITN Site Principal Investigator

Specialty: head & neck cancers
Cleveland Clinic
Cleveland, OH

Ronald Levy, M.D.

CITN Site Principal Investigator

Specialty: lymphomas
Stanford Cancer Center
Stanford, CA

Pamela Ohashi, Ph.D., FRSC

CITN Site Principal Investigator

Specialty: tumor immunity, immune tolerance
University Health Network
Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada

Ann W. Silk, M.D., M.S.

CITN Site Principal Investigator

Dana-Farber Cancer Institute

Mario Sznol, M.D.

CITN Site Principal Investigator

Specialty: skin cancer, prostate and urologic cancers
Yale Cancer Center, New Haven, CT
Smilow Cancer Hospital at Yale-New Haven

Walter J. Urba, M.D., Ph.D.

CITN Site Principal Investigator

Specialty: melanoma
Robert W. Franz Cancer Research Center; Earle A. Chiles Research Institute
Providence Cancer Center, Portland, OR

Edmund Waller, M.D., Ph.D., FACP

CITN Site Principal Investigator

Specialty: leukemia, lymphoma
Wiship Cancer Institute
Emory University, Atlanta, GA

Holden Maecker, Ph.D.

Non-Voting Member

Stanford University

Bob Salim

Statistical Scientist Director, Axio Research
CITN Non-Voting Member

Jeffrey Schlom, Ph.D.

CITN Non-Site Principal Investigator

National Cancer Institute

Deborah Collyar

CITN Non-Site Principal Investigator

PAIR: Patient Advocates in Research

James Kublin, M.D., M.P.H

CITN Non-Site Principal Investigator
Executive Director HVTN, FHCRC

Howard Streicher, M.D.

Project Scientist, NCI/CTEP

Elad Sharon, M.D., M.P.H

Project Scientist, NCI/CTEP

Pediatric CITN Steering Committee

Crystal Mackall

Crystal Mackall, M.D.

Director, Pediatric Cancer Immunotherapy Trials Network, Fred Hutch
Professor, Pediatrics and Internal Medicine, Stanford University
Associate Director, Stanford University Cancer Institute
Leader, Cancer Immunology and Immunotherapy Program, Stanford University
Director, Parker Institute for Cancer Immunotherapy
CITN Site Principal Investigator

Julie R. Park, M.D.

Pediatric CITN Site Principal Investigator

Specialty: pediatric neuroblastoma
Seattle Children’s Hospital, Seattle, WA

John M. Maris, M.D.

Pediatric CITN Site Principal Investigator

Specialty: neuroblastoma
Children’s Hospital of Philadelphia (CHOP), Philadelphia, PA

Daniel Morgenstern, M.D.

Pediatric CITN Site Principal Investigator

Specialty: neuroblastoma
The Hospital for Sick Children
University of Toronto, Toronto, ON, Canada

Paul Sondel, M.D., Ph.D.

Pediatric CITN Site Principal Investigator

Specialty: pediatric leukemia
American Family Children’s Hospital
University of Wisconsin Health Clinics, Madison, WI

Jodi A. Muscal, M.D.

Pediatric CITN Site PI

Specialty: pediatric solid, brain, and rare tumors
Texas Children’s Hospital
Baylor College of Medicine, Houston, TX

Terry Fry, M.D.

Pediatric CITN Site PI

Specialty: pediatric leukemia
Pediatric Oncology Branch
National Cancer Institute/Center for Cancer Research, Bethesda, MD

Kirk Schultz, M.D.

Pediatric CITN Site PI

Specialty: childhood leukemia
Michael Cuccione Childhood Cancer Research Program
BC Children’s Hospital, Vancouver, BC, Canada

Michael Pulsipher, M.D.

Pediatric CITN Site PI

Specialty: pediatric hematology
Children’s Hospital of Los Angeles
Keck School of Medicine, University of Southern California, Los Angeles, CA

Judith Kaiser, M.B.A., B.S.N., R.N.

FHCRC - CITN and ION Administrative Director

Holden Maecker, Ph.D.

Stanford University

Bob Salim, Statistical Scientist Director

Axio Research

Patrick Sullivan

Patient/Family Advocate
Canadian Cancer Trials Group

Mac Cheever, M.D.

FHCRC, CITN and ION Director

Steve Fling, Ph.D.

FHCRC, CITN and ION Laboratory Director

Tom S. Uldrick Jr., M.D., M.S.

FHCRC, Deputy Head, Global Oncology and CITN Program Leader

Nora L. Disis, M.D.

University of Washington, CITN Program Leader

COSC Staff: Internationally-Renowned Cancer Immunology Experts

The Central Operations and Statistical Center (COSC) is directed by Dr. Martin “Mac” Cheever. Fred Hutch researchers Dr. Mary “Nora” Disis and Dr. Thomas S. Uldrick serve as co-directors. COSC staff coordinates the work of CITN and ION member site investigators and research staff across North America. This group provides overall leadership to the CITN andION networks as well as organizational infrastructure, protocol development, statistical design and support for trial coordination.

 

Dr. Mac Cheever

Martin A. (Mac) Cheever, M.D.

Director and Principal Investigator, CITN and ION
Member, Clinical Research Division, Fred Hutch
Professor of Medicine/Oncology, University of Washington
Non-Voting Member
Judy Kaiser

Judith Kaiser, M.B.A., B.S.N., R.N.

Administrative Director
Betty Bertoldi

Betty Bertoldi, B.A.

Project Manager

Anna Wright, PhD

Vaccine Trials Project Manager
Eva Hymel

Eva Hymel, M.S.

Senior Regulatory Affairs Manager

Diana E. Koch, MS, MBA

Regulatory Affairs Coordinator
Melissa Atteberry

Melissa Atteberry, C.P.A.

Fiscal Manager
Andreanne Lacroix

Andreanne Lacroix, B.Sc.

Senior Vaccine Trials Project Manager

Kajari Mondal, PhD

Project Coordinator

Mairah O’Callaghan, MBA

Vaccine Trials Project Manager

CIML Staff (Clinical Staff)

Directed by Dr. Steven Fling, the CITN and ION Immune Monitoring Lab conducts molecular assays and genetic assessments of specimens collected from patients in CITN and ION trials. The lab serves as a central repository for these samples

Steven Fling

Steven Fling, Ph.D.

Director
Dan Schullery

Dan Schullery, M.S.

Associate Director
Chihiro Morishima

Chihiro Morishima, M.D.

Consultant
Harleen Choudhary

Harleen Choudhary, B.S.

Staff Scientist
Leonard D'Amico

Leonard D'Amico, Ph.D.

Staff Scientist
Bruce Hess

Bruce Hess, M.S.

Staff Scientist

Emily Ekdahl

Research Technician

Liz O'Donoghue, B.S.

Staff Scientist

CITN Member Sites