Chromosome Metabolism and Cancer Training Grant

The aim of the Chromosome Metabolism and Cancer Training Grant is to support research training and research projects in the area of chromosome activities and their links to cancer. This includes but is not limited to research on mechanisms of DNA replication, repair, rearrangement and modification; transcription, splicing and RNA modification; chromatin structure and epigenetics; mitosis, chromosome segregation and instability; oncogenes and tumor suppressors; tumor initiation and progression; cell transformation, differentiation, apoptosis and senescence; cell-cell and cell-matrix interactions, adhesion, migration and growth factors; and other areas of chromosome and cancer biology. 

The program supports 8 trainees each year. Trainees are appointed to a National Cancer Institute (NCI) training grant. Trainees design and execute a research project, participate in training program research, take courses in bioinformatics and neoplasia, and present at the annual training program colloquium. Through this program, trainees develop and strengthen scientific core competencies. 

Appointment Details

A Ruth L. Kirschstein National Service Award (NRSA) Institutional Research Training Grant awarded to Fred Hutch by the National Cancer Institute. The grant includes two predoctoral slots and six postdoctoral slots. 

  • Initial appointments to the grant are 12 months long. Trainees must competitively reapply for an additional period of funding. The standard appointment period is November 1–October 31. 
  • Stipends (Kirstchstein-NRSA) and benefits administered by Fred Hutch.
  • In-state tuition (operating fee, 10 credits F/W/S, 2 credits SU) is covered at approximately 60% for predoctoral trainees.
  • Mentors are responsible for covering any shortfalls in trainee costs.

Eligibility

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Open to pre- and postdoctoral trainees at Fred Hutch who are eligible for Kirchstein-NRSA support. Each trainee must be a citizen of the United States, a non-citizen national, or must have been lawfully admitted for permanent residence and possess an Alien Registration Receipt Card (1-151 or 1-551) or some other verification of legal admission as a permanent resident.

Predoctoral trainees must be accepted into the Molecular and Cellular Biology program or other appropriate PhD program at the University of Washington. Trainees must have completed first year of coursework and rotations and be in second/third year of PhD program, or first/second year in thesis lab. Please note we are not able to appoint trainees on staff assignments nor can we support out-of-state tuition.

Postdoctoral trainees with less than three years of training at the point of application are preferred.

Mentors must have documented interests and activities in translational cancer research and/or fundamental molecular and cell biology, be scientifically productive, and able to cover shortfalls in trainee costs. Predoctoral mentors must have an appointment at the University of Washington with graduate training status.

 

We especially encourage applications from underrepresented individuals, individuals with disabilities and individuals from disadvantaged backgrounds.

Frequently Asked Questions

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I am interested in the program and want to apply. When are you accepting applications?

We update the website, post flyers, and send announcements across divisions several weeks prior to the deadline. This usually takes place annually in late summer.

I am a foreign national with a student visa. Can I apply?

Foreign nationals with student visas are not eligible for this award.

What is the time commitment of the program?

Trainees are generally appointed to the program for at least 12-months, with opportunities to re-apply for further funding. They must dedicate at least 40 hours per week (full-time effort) to the program.

I am looking for support for a few months in between fellowships. Can I apply?

The program does not support short-term training.

I am not able to start an appointment on November 1. Can I still apply?

Please consult with the program's administrator regarding your specific situation before applying.

Kirschstein-NRSA awards provide stipends. What is the difference between stipend and salary?

A stipend is not "salary" and is not provided as a condition of employment with either the Federal government or the recipient organization. See NIH Grants Policy Statement 11.3.8.2.

What is the difference between stipend supplementation and additional compensation?

Fred Hutch's Office of Sponsored Research has a page on this topic (requires login). Also see NIH Grants Policy Statement 11.3.10.

2019 Program Schedule

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Date Time Location Activity
January 31 11-12 M4-A805/A817 Trainee Meeting: Introductions & IDPs
February 28 11-1 M4-A805/A817 Trainee Meeting: Victor Bii, Andrew Bondesson, Nithya Kartha
February 28 5pm - Individual Development Plans Due
Mid-March - - List of speakers for next year due
April 11 11-12 A1M-025 Journal Club: Anjana Rao
April 16 12-1 Pelton Auditorium Current Bio Seminar Speaker: Anjana Rao, La Jolla Institute for Immunology
April 25 1-3 E3-200/201 Trainee Meeting: Laura Jackson, Tonibelle Gatbonton-Schwager, Kelsey Lynch
May 10 12-1 A2M-025 Journal Club: Craig Mello
May 14 12-1 Pelton Auditorium Current Bio Seminar Speaker: Craig Mello, University of Mass. Medical School
May 31 5pm - Trainee Progress Reports Due
June 13 11-1 M5-C813/815 Trainee Meeting: Jake Polaski, Christine Cucinotta
August 31 5pm - Updated Trainee Progress Reports Due
Sept. TBD - - "Giving Scientific Presentations" by Sue Biggins
October 3 12-5 E3-200/201 Annual Colloquium: Schedule TBD

 

 

Other Requirements

Bioinformatics/Coding Courses:  Available via fredhutch.io, courses will be available throughout 2019. Trainees will be alerted to course offerings as soon as available. Register through Hutch Learning. 

Responsible Conduct of Research:  To learn more, visit the Training & Organization Development's Research Ethics Education Program site (requires login).

Science Writing Workshops:  TBD

We are currently accepting applications. Complete applications are due Wednesday, September 18 at 12pm.

How to Apply

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Instructions
  1. Complete the application form along with your biosketch, research proposal, and mentor letters.
  2. Combine all application components into a single PDF with the naming structure "Lastname_CMCTG-Application_Date.pdf"
  3. Email your complete application to the training grant administrator.
Application Components
Biosketch Provide details of your academic training and any relevant research and work experience. Please use the fellowship version of the NIH biosketch format.
Research Proposal

Describe how your proposed research project relates to cancer biology and how it reflects the goals of the training program. Format your proposal to include specific aims, significance, innovation, and approach sections. Your abstract will be entered directly into the application form.

  • Page Limit: 2 pages of text (figures/references do not count toward the limit and should be on up to 2 separate pages)
  • Margins: 0.75”
  • Font: Arial, 11pt
Mentor Letter

A letter is required from the mentor and should:

  • Assess the applicant’s strengths.
  • Discuss how the proposed training program will further enhance the applicant’s professional and academic development.
  • Describe a unique and well-developed training plan for the applicant, including experimental goals for the upcoming year.
  • If the proposed mentor is an assistant member, include a brief description of how the mentor receives advice on mentorship from senior colleagues.

The mentor should also confirm they have sufficient and appropriate funding to cover shortfalls in trainee costs, such as supplies, equipment, and/or other research expenses; additional compensation or supplementation; tuition and benefits.

Mentors may submit letters directly to the program’s administrator. If they do, applicants must indicate this in the last section of the application form under “Additional Comments.”

Additional Letters of Recommendation (2)

Up to two additional letters of recommendation may be included in the application package. These letters should:

  • Assess the applicant’s strengths.
  • Discuss how the proposed training program will further enhance the applicant’s professional and academic development.

Letters may be sent directly to the program’s administrator. If author’s do submit separately, applicants must indicate this in the last section of the application form under “Additional Comments.”

New Mentor Information

If the proposed mentor is not currently involved in the program (see faculty page):

  • Include the proposed mentor's biosketch in the application package. Section A does not need to be tailored to the application. The purpose of the biosketch is to review the mentor's contributions to science as well as their research support to ensure compatibility with the training grant.
  • Complete the mentor record table in the application form summarizing the proposed mentor's training record.

Other programs

Not the right fit? Explore our other internships and programs.

Contact us

Anissa Barker

Administrator

Bob Eisenman

Program Director

Toshi Tsukiyama

Program Co-Director