Translational Science and Therapeutics Jobs

Assistant or Associate Professor, Department of Pathology, Pathologist, on clinician scholar pathway with an approximate 50:50 contribution to clinical service and academic pursuits.

The Fred Hutchinson Cancer Center (Fred Hutch) and the University of Washington (UW) are jointly recruiting a full-time faculty member at the Assistant Professor or Associate Professor level without tenure due to funding (WOT), commensurate with experience and qualifications in the Translational Science & Therapeutics Division of the Fred Hutch and the Department of Laboratory Medicine & Pathology (DLMP), School of Medicine at the UW. This position would have an annual service period of 12 months [July 1-June 30]. The primary appointment will be in the Translational Science & Therapeutics Division of Fred Hutch.

The selected individual for the advertised position is expected to contribute to our mission of delivering outstanding clinical care and developing excellence in clinical research in anatomic pathology/clinical pathology. We seek candidates with expertise in hematopathology and molecular pathology and with interest and experience in pathology related to stem cell transplant and immunotherapy. Interest and expertise in pathology and genomics of lymphoid neoplasms would be preferred. Based on the qualifications, this position could entail a leadership role as medical director of a laboratory location. The person may also have an opportunity to participate in deep immunophenotyping and cell sorting for genomic investigations. Fred Hutch and University of Washington faculty engage in teaching, research, and service. Teaching responsibilities will involve the delivery of informal teaching sessions and formal lectures to providers and the general medical community.

Faculty are expected to perform their primary activities on-site at Fred Hutch.

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

Anticipated Start Date: FY26 (July 1, 2025 – June 30, 2026)

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Bioinformatics Analyst I-II will provide data analysis services to researchers in the Dhodapkar lab, particularly focusing on single cell genomics, integration of high-dimensional immunologic data and genome sequencing. This position requires the ability to work independently, manage multiple overlapping demands, and communicate effectively with faculty, post-doctoral fellows, and research staff on a wide range of topics in biology, analytical biochemistry, sound experimental design, and data science. The Bioinformatics Analyst works closely with Shared Resources cores, especially Genomics and Hutch Data core, to ensure that data quality is high and that users have access to advice and continuing dialog as they review results. Given the large volumes and diverse types of data generated and integrated in Bioinformatics projects, practical applied programming skills are also essential.

At Fred Hutchinson Cancer Center, all employees are expected to demonstrate a commitment to our values of collaboration, compassion, determination, excellence, innovation, integrity, and respect.

Responsibilities

• Analyze large sequence datasets from diverse workflows including exome capture, RNA-seq, single cell sequencing, ATAC-seq, and CRISPR screens.
• Work with Hutch scientists to refine computational research questions and develop analytical processes that can be applied to these genomic datasets.
• Consult with researchers on sound experimental design.
• Identify appropriate bioinformatics tools to meet the needs of proposed projects.
• Partner with researchers who are developing novel assays to design appropriate processing and analysis workflows.
• Review current literature to identify and adopt software and methodologies, making new analysis capabilities available to the team.
• Provide figures and written sections to document methods and results for manuscripts, presentations, and grant applications.
• Collaborate with colleagues in the Genomics Shared Resource and the Hutch Data Core to ensure the integrity and consistency of primary data, track experimental methods and metadata, define standardized analysis pipelines, and provide support as stakeholders analyze and interpret results.
• Train laboratory members and collaborators on analytic workflows.
• Upload and maintain datasets, workflows, and code (for example GEO, Github).
• Other duties as assigned.

Qualifications

MINIMUM QUALIFICATIONS

Bioinformatics Analyst I:

• Bachelor’s degree in bioinformatics, computational biology, genetics, or related field.
• Some experience in computational analysis of large, complex sequence-based molecular data sets.
• Demonstrated proficiency in R and Python 3 are essential.
• Familiarity with workflow and scheduling software (e.g., Slurm).
• Excellent written and verbal communication skills.

Bioinformatics Analyst II:

• Bachelor’s degree in bioinformatics, computational biology, genetics, or related field with at least three years’ direct experience in computational analysis of large sequence-based molecular data sets.
• Direct experience must include best-practice germline & somatic variant calling from exome capture data, analysis of bulk RNA-seq data with multiple contrasts, analysis of multimodal single-cell profiling data, epigenetic profiling, gene set enrichment, and integration of data across multiple modalities (e.g., epigenetic profiling and RNA-seq).
• Effective use of shell scripting and significant fluency in R and Python 3 are essential.
• Facility with commonly used Bioconductor packages, ggplot, tidyverse etc.
• Ability to generate and customize common data visualizations (PCA plots, volcano plots, Circos plots, etc).
• Familiarity with workflow and scheduling software (e.g. Slurm).
• Excellent written and verbal communication skills are absolutely required.

PREFERRED QUALIFICATIONS

Bioinformatics Analyst I: 

• A year of more of direct experience in computational analysis of large, complex sequence-based molecular data sets.

Bioinformatics Analyst II: 

• Master’s degree in bioinformatics, computational biology, genetics, or related field.
• Two+ years of experience in software development, data engineering, data science, or related field with a track record of manipulating, processing, and extracting value from large datasets.
• Experience with single cell transcriptomic analyses and associated pipelines. (e.g. Seurat).
• Direct experience includes whole exome sequencing, and integration of data across multiple modalities (e.g., TCR-seq, CITE-seq, ChIP-seq, ATAC-seq, and CRISPR/Cas9 knockout screens).

Bioinformatics Analyst I:  The annual base salary range for this position is from $77,976 to $102,211, and pay offered will be based on experience and qualifications.  

Bioinformatics Analyst II:  The annual base salary range for this position is from $78,894 to $118,310, and pay offered will be based on experience and qualifications.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). 

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Bioinformatics Analyst I-II will provide data analysis services to researchers in the Dhodapkar lab, particularly focusing on single cell genomics, integration of high-dimensional immunologic data and genome sequencing. This position requires the ability to work independently, manage multiple overlapping demands, and communicate effectively with faculty, post-doctoral fellows, and research staff on a wide range of topics in biology, analytical biochemistry, sound experimental design, and data science. The Bioinformatics Analyst works closely with Shared Resources cores, especially Genomics and Hutch Data core, to ensure that data quality is high and that users have access to advice and continuing dialog as they review results. Given the large volumes and diverse types of data generated and integrated in Bioinformatics projects, practical applied programming skills are also essential.

At Fred Hutchinson Cancer Center, all employees are expected to demonstrate a commitment to our values of collaboration, compassion, determination, excellence, innovation, integrity, and respect.

Responsibilities

• Analyze large sequence datasets from diverse workflows including exome capture, RNA-seq, single cell sequencing, ATAC-seq, and CRISPR screens.
• Work with Hutch scientists to refine computational research questions and develop analytical processes that can be applied to these genomic datasets.
• Consult with researchers on sound experimental design.
• Identify appropriate bioinformatics tools to meet the needs of proposed projects.
• Partner with researchers who are developing novel assays to design appropriate processing and analysis workflows.
• Review current literature to identify and adopt software and methodologies, making new analysis capabilities available to the team.
• Provide figures and written sections to document methods and results for manuscripts, presentations, and grant applications.
• Collaborate with colleagues in the Genomics Shared Resource and the Hutch Data Core to ensure the integrity and consistency of primary data, track experimental methods and metadata, define standardized analysis pipelines, and provide support as stakeholders analyze and interpret results.
• Train laboratory members and collaborators on analytic workflows.
• Upload and maintain datasets, workflows, and code (for example GEO, Github).
• Other duties as assigned.

Qualifications

MINIMUM QUALIFICATIONS:

Bioinformatics Analyst I:

• Bachelor’s degree in bioinformatics, computational biology, genetics, or related field.
• Some experience in computational analysis of large, complex sequence-based molecular data sets.
• Demonstrated proficiency in R and Python 3 are essential.
• Familiarity with workflow and scheduling software (e.g., Slurm).
• Excellent written and verbal communication skills.

Bioinformatics Analyst II:

• Bachelor’s degree in bioinformatics, computational biology, genetics, or related field with at least three years’ direct experience in computational analysis of large sequence-based molecular data sets.
• Direct experience must include best-practice germline & somatic variant calling from exome capture data, analysis of bulk RNA-seq data with multiple contrasts, analysis of multimodal single-cell profiling data, epigenetic profiling, gene set enrichment, and integration of data across multiple modalities (e.g., epigenetic profiling and RNA-seq).
• Effective use of shell scripting and significant fluency in R and Python 3 are essential.
• Facility with commonly used Bioconductor packages, ggplot, tidyverse etc.
• Ability to generate and customize common data visualizations (PCA plots, volcano plots, Circos plots, etc).
• Familiarity with workflow and scheduling software (e.g. Slurm).
• Excellent written and verbal communication skills are absolutely required.

PREFERRED QUALIFICATIONS:

Bioinformatics Analyst I: 

• A year of more of direct experience in computational analysis of large, complex sequence-based molecular data sets.

Bioinformatics Analyst II: 

• Master’s degree in bioinformatics, computational biology, genetics, or related field.
• Two+ years of experience in software development, data engineering, data science, or related field with a track record of manipulating, processing, and extracting value from large datasets.
• Experience with single cell transcriptomic analyses and associated pipelines. (e.g. Seurat).
• Direct experience includes whole exome sequencing, and integration of data across multiple modalities (e.g., TCR-seq, CITE-seq, ChIP-seq, ATAC-seq, and CRISPR/Cas9 knockout screens).

Bioinformatics Analyst I: The annual base salary range for this position is from $68,162 to $102,211, and pay offered will be based on experience and qualifications. 

Bioinformatics Analyst II: The annual base salary range for this position is from $78,894 to $118,310, and pay offered will be based on experience and qualifications.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). 

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Bioinformatics Analyst III will provide data analysis services to researchers in the Fred Hutch Clinical Testing Labs - Molecular OncologyXXXX lab, particularly focusing on molecular, single cell genomics, integration of high-dimensional immunologic data and genome sequencing. This position requires the ability to work independently, manage multiple overlapping demands, and communicate effectively with faculty, lab managers, lab staff, staff scientist, and research staff on a wide range of topics in biology, analytical biochemistry, sound experimental design, and data science. The Bioinformatics Analyst will work closely with the medical director, clinical laboratory director, and MO staff for clinical variant analysis as well as development and execution of small programming and database projects related to the data analysis workflows needed for the Fred Hutch clinical testing labs.  The BA is also expected to work closely with NIH teams, Fred Hutch IT teams, Shared Resources cores, especially Genomics and Hutch Data core, and as needed SWOG data teams, to ensure that data quality is high and that users have access to advice and continuing dialog as they review results. Given the large volumes and diverse types of data generated and integrated in Bioinformatics projects, practical applied programming skills are also essential.

Responsibilities

PRIMARY/ESSENTIAL DUTIES:

• Supports the maintenance of computational infrastructure and the flow of samples and information for large-scale studies in compliance with applicable FDA, NYS-DOH, CLIA, and CAP regulations.
• Contribute to web-based bioinformatics (both public and internal relational databases), and assists in the development as well as the application of computational tools.
• Interpret complex biological information, conduct statistical and genomic analysis.
• Write custom scripts to access databases, perform and evaluate quality control and analyze sequencing data (must be proficient with NGS, LRS data would be a desirable skill).
• Assist in the development and refinement of data analysis and integration methodology and pipelines. Must have ability to write scripts automating data transfers to and from AWS and other databases, and can incorporate API.
• Analyze large sequence datasets from diverse workflows including exome capture, RNA-seq, single cell sequencing, ATAC-seq, and CRISPR screens.
• Work with Hutch scientists to refine computational research questions and develop analytical processes that can be applied to these genomic datasets.
• Consult with researchers on sound experimental design.
• Identify appropriate bioinformatics tools to meet the needs of proposed projects.
• Partner with researchers who are developing novel assays to design appropriate processing and analysis workflows.
• Review current literature to identify and adopt software and methodologies, making new analysis capabilities available to the team.
• Provide figures and written sections to document methods and results for manuscripts, presentations, and grant applications.
• Collaborate with colleagues in the Genomics Shared Resource and the Hutch Data Core to ensure the integrity and consistency of primary data, track experimental methods and metadata, define standardized analysis pipelines, and provide support as stakeholders analyze and interpret results.
• Train laboratory members and collaborators on analytic workflows.
• Upload and maintain datasets, workflows, and code (for example GEO, Github).
• Excellent written and oral communication skills  - required for manuscripts, grant, presentation, preparation.
• Candidate must demonstrate outstanding personal initiative and creativity in problem solving.
• Other duties as assigned.

SCOPE OF RESPONSIBILITY:

• Level of autonomy: A senior level position that works under minimal supervision, works on and completes  complex projects requiring advanced knowledge and skills. Ability to conduct clinical variant analysis as part of the clinical data review team,  manage multiple overlapping demands, work independently as well as balance their own schedules, and communicate effectively with faculty, managers, lab staff, and research staff on a wide range of topics in molecular biology, analytical biochemistry, sound experimental design, and data science.
• Financial responsibility: None

Qualifications

MINIMUM QUALIFICATIONS:

• Bachelor’s degree in bioinformatics, computational biology, genetics, or related field.
• At least three years’ direct experience in computational analysis of large, complex sequence-based molecular data sets.
• Two+ years of experience in software development, data engineering, data science, or related field with a track record of manipulating, processing, and extracting value from large datasets.
• Direct experience must include whole exome sequencing, analysis of bulk RNA-seq data with multiple contrasts, analysis of multimodal single-cell immune repertoire profiling data, gene set enrichment, and integration of data across multiple modalities (e.g., epigenetic profiling, TCR-seq, CITE-seq, ChIP-seq, ATAC-seq, and CRISPR/Cas9 knockout screens).
• Demonstrated fluency in R and Python 3 are essential.
• Proficiency with Linux/Unix shell scripting (e.g., bash).
• Facility with commonly used Bioconductor packages, ggplot, tidyverse etc.
• Ability to generate and customize common data visualizations (PCA plots, volcano plots, Circos plots, etc).
• Familiarity with workflow and scheduling software (e.g., Slurm).
• Excellent written and verbal communication skills.

PREFERRED QUALIFICATIONS:

• Master’s degree in bioinformatics, computational biology, genetics, or related field.
• Experience handling data in compliance with FDA, NYS-DOH, CAP, and CLIA regulations.

The annual base salary range for this position is from $95,888 to $143,811, and pay offered will be based on experience and qualifications.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Meshinchi Lab in the Translational Science and Therapeutics Division at Fred Hutchinson Cancer Center, led by Dr. Soheil Meshinchi, focuses on developing targeted immunotherapies for pediatric acute myeloid leukemia (AML) by identifying leukemia-specific cell surface proteins suitable for CAR T-cell therapy. Their research has expanded to include other cancers, such as osteosarcoma, by leveraging shared molecular targets like folate receptor alpha (FOLR1) to design novel treatments.

Responsibilities

The Lab Aide will be responsible for general laboratory support, including preparing stock solutions, maintaining the lab environment, and disposing of biohazard waste.

• Prepare media and reagents, such as stock solutions
• Restock lab supplies
• Empty biohazard waste
• May assist with experiments, including maintenace of cell lines, DNA and RNA extraction, PCR, qPCR
• Perform other related duties as assigned

This is a temporary, part-time position for a fixed duration.

Qualifications

MINIMUM QUALIFICATIONS:

• Graduation from High School or equivalent with interest in the sciences.

PREFERRED QUALIFICATIONS:

• Enrollment in a university-level science degree program (e.g. biology, chemistry, or biochemistry).
• Demonstrated accuracy, attention to detail, and ability to learn new skills quickly is essential.
• Previous or current coursework in biology and/or chemistry and past laboratory experience.

The hourly pay range for this position is from $20.76 to $29.54 and pay offered will be based on experience and qualifications.

Fred Hutchinson Cancer Center offers employees access to a retirement savings plan, an employee assistance program, paid sick leave (1 hour for every 30 hours worked), and prorated paid holidays (up to 11 days per year).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Warren Lab in the Program in Immunology in the Translational Research and Therapeutics Division at the Fred Hutchinson Cancer Center has an opportunity for an undergraduate biosciences-related major seeking to enhance their academic pursuits to participate in a Research Internship. Available projects include 1) learning how to engineer human T cells with tumor antigen-specific T-cell receptors and chimeric antigen receptors and evaluating their preclinical tumor-specific cytotoxicity; and 2) learning how to isolate clonally expanded T-cell populations from tumors and optimizing their ex vivo expansion to maintain non-exhausted, memory-like, tumor-reactive T cells. We are looking for students with an excellent academic record seeking to gain original research experience in support of their academic goals. Candidates must be organized and reliable with a strong attention to detail and a passion for research.

This is an unpaid internship position. Students must be able to earn research course credits through their undergraduate program and are encouraged to apply for independent scholarship support. We are seeking a student that can begin in the Summer quarter and attend the lab at least 12 hours per week. 

Responsibilities

The intern will work under the direction of the Principal Investigator and senior-level laboratory personnel. They will gain experience and training in experimental design, execution, and analysis while assisting their mentor with the goal of increasing independence. Available projects include 1) learning how to engineer human T cells with tumor antigen-specific T-cell receptors and chimeric antigen receptors and evaluating their preclinical tumor-specific cytotoxicity; and 2) learning how to isolate clonally expanded T-cell populations from tumors and optimizing their ex vivo expansion to maintain non-exhausted, memory-like, tumor-reactive T cells.

The internship is part-time and requires a minimum commitment of at least 12 hours per week during the Summer quarter.

Qualifications

MINIMUM QUALIFICATIONS:

• A motivated biosciences-related undergraduate student with a passion for performing original research.

PREFERRED QUALIFICATIONS:

• Previous lab experience in biology / biochemistry.

Application Instructions:

Please submit a cover letter including a brief description of your interests and academic goals, a CV, and at least one reference. We will invite selected students to interview as soon as the week of June 6th.

This is an unpaid internship, receiving undergraduate research credits. 

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Paulovich Lab at Fred Hutch (https://research.fredhutch.org/paulovich/en.html) is an interdisciplinary team whose mission is to develop and implement tools for protein quantification to enable precision medicine via patient selection and characterization of novel therapeutic targets. The lab has a major focus on mass spectrometry (MS)-based proteomics (both untargeted and targeted), as well as integrating proteomic data with genomic data. Our group is highly collaborative, participating in national and international consortia in which teams of scientists, statisticians, and clinicians work together to solve clinical or biological problems to impact human health.

This is a terrific opportunity within the Paulovich lab for a highly motivated full-time Post-Doctoral Research Fellow to join our translational proteomics team to help drive translational projects forward towards clinical applications by performing bench-level experiments in support of proteomic, genomic, and transcriptomic analyses of clinical and preclinical biospecimens. The ideal candidate will be able to work as part of a team as well as independently to follow established standard operating protocols (SOP) in a CLIA/CAP laboratory environment.

Responsibilities

• Work with antibodies (immunoaffinity purification, immobilization on solid supports, ELISAs)
• Process proteomic samples for LC-MS analysis (e.g., protein extraction, fractionation, immuno-depletion, trypsin digestion, alkylation, reduction, etc.)
• Assist in generation and analysis of mass spectrometry (MS)-based proteomic data
• Follow standard operating protocols (SOP) in a CLIA/CAP laboratory environment including participating in annual competency and proficiency testing
• Collaborate effectively with an interdisciplinary team spanning expertise in medicine, biology, analytical chemistry, and statistics
• Maintain laboratory equipment, records, research results files, and databases
• Write progress reports and develop standard operating protocols (SOPs)
• Write and co-author scientific manuscripts (in peer-reviewed journals)
• Design and present Powerpoint presentations from results to colleagues and collaborators
• Work comfortably in a milestone-driven environment, with quarterly objectives
• Perform other duties as required

Qualifications

MINIMUM QUALIFICATIONS:

• Ph.D. degree in Protein Chemistry, Analytical Chemistry, Biochemistry, or related discipline
• Previous work maintaining mass spectrometry and HPLC instruments

PREFERRED QUALIFICATIONS:

• Exquisite attention to detail and the ability to adhere to standard operating protocols (SOP) and maintain records
• Excellent English writing and oral communication skills
• Proficiency with MS Office programs (Word, Powerpoint, Excel, and Access)
• Ability to multi-task efficiently in a highly interactive, interdisciplinary team environment
• Comfort in a milestone-driven environment, with quarterly objectives
• Willingness to learn new techniques
• Strong work ethic
• Previous experience in a CLIA/CAP or similar clinical lab environment
• Experience with LIMS, database software and proteomics tools
• Previous work with antibodies and peptide standards (immunoaffinity purification, immobilization on solid supports, screening hybridomas for mass spectrometry)
• Previous work in proteomics, genomics, and functional biology
• Previous experience with liquid handling robot usage and programming
• Ability to perform molecular biology and biochemistry experiments on human and animal biospecimens and cell lines

The annual base salary range for this position is from $77,976.00 to $95,014.40 and pay offered will be based on experience and qualifications.

This position may be eligible for relocation assistance.

This position may be eligible for sign on bonus.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. 

Responsibilities

The Geoff Hill Lab, in Seattle’s Fred Hutchinson Cancer Center Translational Science & Therapeutics Division, is recruiting a Post-Doctoral Research Fellow with expertise in transplant immunology and/or immunotherapy. The candidate will have the opportunity to contribute to multiple NIH funded research programs, including studies defining the mechanisms of cancer-specific immunity versus immune escape and pathogen-specific immunity after adoptive cell therapy. There are also active programs defining  mechanisms of, and innovative treatment paradigms for immune toxicity (e.g. graft-versus-host disease and cytokine release syndrome) after stem cell transplantation and adoptive cell therapy.

Qualifications

MINIMUM QUALIFICATIONS:

• MD or PhD in a related field
• A strong foundation in immunology and cell biology
• A track record of productive research

 PREFERRED QUALIFICATIONS:

•  Expertise in cellular immunology and a background in bone marrow/stem cell transplantation and/or immunotherapy

The annual base salary range for this position is from $77,976 to $95,014.40 and pay offered will be based on experience and qualifications. This position may be eligible for relocation assistance. 

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Ring Lab of Synthetic and Systems Immunopharmacology is located within the Translational Science and Therapeutics Division and is a member of the Immunotherapy Integrated Research Center (IIRC). Their primary focus is on developing unique and first-in-class therapeutic drugs for cancer immunotherapy using cutting-edge protein engineering with directed evolution. The lab has developed therapeutics that are currently in clinical trials, such as ST-067 (a "decoy-resistant" IL-18), MDNA-11 (CD122-biased IL-2), and ALX-148/evorpacept (an ultra-high affinity SΙRPα decoy). Moreover, the Ring Lab is actively working on developing platforms for identifying new targets in cancer immunotherapy. These technologies include the REAP platform for discovering autoantibodies in patient samples, and high-throughput techniques in synthetic antibody engineering and proteogenomics to pinpoint new tumor antigens.

Responsibilities

The Ring Lab is recruiting a Post-Doctoral Research Fellow with expertise in immunology, systems/computational biology, and/or protein engineering. This position will involve research projects that investigate the relationship between patient autoantibodies and health and disease outcomes. At the core of these programs is the REAP autoantibody profiling technology, which provides unprecedented levels of detail about the "autoantibody reactome" present in patient blood and tissue samples. Researchers will perform the very first "autoantibody-wide association studies" to pinpoint how specific autoantibody reactivities impact disease biology, analogous to but independent from the effect of genetic variation. This entirely new research program is poised to identify novel therapeutic targets for a range of indications including cancer, autoimmune disease, inflammatory conditions such as IBD, infectious disease, and neurodegeneration.

The ideal candidate will be a highly-curious, motivated, independent, and collaborative research scientist keen to explore new areas of biology and therapeutic development. They will work closely with Dr. Ring, lab manager Alison Notestine, external collaborators, and other members of the Ring laboratory to execute highly-multidisciplinary studies. Furthermore, they will have the opportunity and responsibility to contribute to the preparation of research reports and scientific manuscripts, as well as present at scientific conferences and symposiums. The Ring lab welcomes candidates with a diverse range of career aspirations and has a track-record of supporting trainees to pursue careers in academia, biotech/pharma, life-science investing, and consulting.

Qualifications

MINIMUM QUALIFICATIONS:

• MD or PhD in a related field
• Broad experience in molecular and cell biology methods and the ability to master new techniques and approaches
• Excellent verbal and written communication skills
• A team player with strong aptitude for collaboration

PREFERRED QUALIFICATIONS:

• Experience in one or more of the following areas:
  • Immunology
  • Systems biology/bioinformatics
  • Single cell transcriptomics/proteogenomics
  • Protein engineering/directed evolution with yeast, phage, or mRNA/ribosome display technology
• Experience with mouse models is desirable

The annual base salary range for this position is from $77,976 to $95,014.40 and pay offered will be based on experience and qualifications.

This position may be eligible for relocation assistance.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The focus of research conducted in Dr. William Grady’s laboratory in the Translational Science and Therapeutics Division of Fred Hutch is the study of the molecular and cell biology of gastrointestinal cancer as well as the role of genetic and epigenetic alterations in cancer.

Responsibilities

Under general supervision of the PI and senior post-doctoral fellows in the lab, the Research Technician will perform varied support functions requiring knowledge and skills specific to the research study.

Job responsibilities will include the following:

• Collection and processing of human and mouse tissue samples
• DNA, RNA extraction from fresh frozen or formalin fixed paraffin-embedded human tissue samples
• Proficient with real-time PCR technology
• Protein extraction, cell fractionation, western blot, and immunoprecipitation
• Responsible for the organization of specimen inventory in short-term and long-term storage
• In vitro cell culture experiments
• Mouse husbandry/colony management with transgenic and conditional knock-out mice
• Maintain a database used for organizing the current inventory and tracking the location of specific information/specimens
• Collect and analyze data
• Monitor adherence to study protocol
• Inform PI of deviations from study protocol
• Attend project meetings
• Keep detailed records for experiments
• Maintain a high level of accuracy for all work
• Perform other duties as assigned

Qualifications

MINIMUM QUALIFICATIONS:

• Bachelor’s degree in one of the biological sciences with strong background in molecular biology and cell biology, or equivalent combination of education and experience
• Demonstrated scientific knowledge in the area of study
• Demonstrated basic laboratory skills

PREFERRED QUALIFICATIONS:

• Highly self-motivated and trustworthy.
• Willingness to take up new skills and responsibilities.
• Ability to follow instructions.
• Capability of working independently in a teamwork environment.
• Have excellent interpersonal and communication skills. 
• Competency with Microsoft Excel, Word, and PowerPoint, and Adobe Photoshop

The hourly pay range for this position is from $22.87 to $32.56 and pay offered will be based on experience and qualifications.

This position may be eligible for relocation assistance.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Stem Cell and Gene Therapy (SCGT) program is recruiting a Research Technician I-II with a focus on bench research to participate in the development of gene and cell therapies to treat HIV or other diseases.

Responsibilities

Duties may include processing and analysis of primary blood and tissue samples for flow cytometry, PCR, sterile cell culture work with a focus on primary B cells. The position involves additional responsibilities, such as B cell manufacture, culture/analysis of cells infected with HIV and related viruses and data analysis. The candidate should be motivated to participate in sample processing and analysis from preclinical modeling experiments. This position affords the motivated technician an opportunity to develop/utilize both tissue culture and molecular biology skills. The candidate must also be comfortable working with potentially infectious material and biosafety level 2+ techniques.

Qualifications

Research Technician I:

MINIMUM QUALIFICATIONS

• Bachelor’s degree in related scientific field or equivalent combination of education and experience
• Demonstrated scientific knowledge in the area of study
• Demonstrated basic laboratory skills

PREFERRED QUALIFICATIONS:

• Two years of laboratory experience.
• Experience with cell culture and/or molecular biology techniques e.g. PCR.
• Previous experience using blood processing.
• Knowledge or experience maintaining and ordering materials in addition to excellent record keeping skills.
• Be highly motivated, possess a high level of initiative and attention to details.
• Possess excellent organizational and communication skills (written and oral) plus an ability to work well in a multidisciplinary team environment.
• Familiarity with computer programs including Microsoft Office, FlowJo, Graphpad Prism, and/or similar products.

Research Technician II:

MINIMUM QUALIFICATIONS

• Bachelor's degree in related scientific field or equivalent combination of education and experience
• 2 years of experience working in a lab outside of school coursework

PREFERRED QUALIFICATIONS:

• Master’s degree in biological science.
• Previous experience using primary B cells, Crispr-Cas9 editing and ELISA.
• Experience with cell culture, multicolor flow cytometry, and/or molecular biology techniques e.g. quantitative PCR.
• Excellent organizational and communication skills (written and oral) plus an ability to work well in a multidisciplinary team environment.
• Highly motivated, possess a high level of initiative and attention to details.
• Knowledge or experience maintaining and ordering materials in addition to excellent record keeping skills.
• Familiarity with computer programs including Microsoft Office, FlowJo, Graphpad Prism, and/or similar products.

Research Technician I: The hourly pay range for this position is from $22.87 to $32.56 and pay offered will be based on experience and qualifications. 

Research Technician II: The hourly pay range for this position is from $26.48 to $37.70 and pay offered will be based on experience and qualifications.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Bernstein Lab is recruiting a Research Technician I or II to perform routine laboratory tasks and experiments to help support a lab under the supervision of the Principal Investigator. 

Responsibilities

• Tissue culture maintenance
• Protein expression and purification
• Antibody screening
• Basic flow cytometry assays
• Re-stocking lab supplies
• Processing biohazard waste
• Making reagents

Qualifications

Research Technician I:

MINIMUM QUALIFICATIONS:

• Bachelor’s degree in Immunology, Virology, Molecular Biology, or similar, or equivalent combination of education and experience
• Demonstrated scientific knowledge in the area of study
• Demonstrated basic laboratory skills

PREFERRED QUALIFICATIONS:

• Independent research experience separate from school lab experience

Research Technician II:

MINIMUM QUALIFICATIONS:

• Bachelor’s degree in Immunology, Virology, Molecular Biology, or similar, or equivalent combination of education and experience
• 2 years of experience working in a lab outside of school coursework

PREFERRED QUALIFICATIONS:

• Competency in basic tissue culture, molecular biology techniques such as PCR, qPCR and gel electrophoresis, and a familiarity with current understanding of HIV
• Detail oriented, well-organized, self-motivated, and able to efficiently manage time and experiments
• Strong communication skills
• Prior experience in cell subset isolation from peripheral blood
• Prior experience in multi-parametric flow-cytometric phenotyping of human samples, particularly FACS sorting and analysis using FlowJo
• Prior experience in computational analysis using R/Python/equivalent, or willingness to learn
• Familiarity with biosafety 2 and 2/3 laboratory practices and bloodborne pathogen preventions
• Being comfortable working with rare and important primary human biologic specimens

PREFERRED QUALIFICATIONS FOR BOTH LEVELS:

• An undergraduate degree in a science related field, with prior introductory biology and chemistry.
• A basic understanding of antibodies, protein expression, and cell signaling.
• Willingness to commit to a position for one year.
• To be successful in this position, the technician must be detailed oriented, organized, capable of maintaining thorough records, and be able to work efficiently under supervision.
• Attendance of lab meetings and involvement in a research project will be encouraged.

Please include a brief cover letter describing your interest in this role.

Research Technician I: The hourly pay range for this position is from $22.87 to $32.56 and pay offered will be based on experience and qualifications.

Research Technician II: The hourly pay range for this position is from $26.48 to $37.70 and pay offered will be based on experience and qualifications.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Stem Cell and Gene Therapy (SCGT) program is recruiting a Research Technician II with a focus on bench research.

Responsibilities

Duties may include processing and analysis of primary blood and tissue samples for flow cytometry, PCR, sterile cell culture work with a focus on primary T cells. The position involves additional responsibilities, such as CAR T cell manufacture, culture/analysis of CAR T cells and data analysis. The candidate should be motivated to participate in sample processing and analysis from preclinical modeling experiments to large animal studies. This position affords the motivated technician an opportunity to develop/utilize both tissue culture and molecular biology skills. The candidate must also be comfortable working with potentially infectious material and biosafety level 2+ techniques.

Qualifications

MINIMUM QUALIFICATIONS:

• Bachelor’s degree in biological science or equivalent combination of education and experience
• 2 years of experience working in a lab outside of school coursework
• Previous experience using primary B cells, Crispr-Cas9 editing and ELISA.
• Experience with cell culture, multicolor flow cytometry, and/or molecular biology techniques e.g. quantitative PCR.

PREFERRED QUALIFICATIONS:

• Master’s degree in biological science.
• Excellent organizational and communication skills (written and oral) plus an ability to work well in a multidisciplinary team environment.
• Highly motivated, possess a high level of initiative and attention to details.
• Capable of working independently on multiple projects in a team environment.
• Knowledge or experience maintaining and ordering materials in addition to excellent record keeping skills.
• Familiarity with computer programs including Microsoft Office, FlowJo, Graphpad Prism, and/or similar products.

The hourly pay range for this position is from $26.48 to $37.70 and pay offered will be based on experience and qualifications.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months).

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Paulovich Lab at Fred Hutch (https://research.fredhutch.org/paulovich/en.html) is an interdisciplinary team whose mission is to develop and implement tools for protein quantification to enable precision medicine via patient selection and characterization of novel therapeutic targets. The lab has a major focus on mass spectrometry (MS)-based proteomics (both untargeted and targeted), as well as integrating proteomic data with genomic data. Our group is highly collaborative, participating in national and international consortia in which teams of scientists, statisticians, and clinicians work together to solve clinical or biological problems to impact human health.

This is a terrific opportunity within the Paulovich lab for a highly motivated and upper level full-time Research Technician to join our translational proteomics team to help drive translational projects forward toward clinical applications by performing bench-level experiments in support of proteomic, genomic, and transcriptomic analyses of clinical and preclinical biospecimens. The ideal candidate will be able to work as part of a team as well as independently to follow established standard operating protocols (SOP) in a CLIA/CAP laboratory environment.

Responsibilities

• Work with antibodies (immunoaffinity purification, immobilization on solid supports, ELISAs)
• Process proteomic samples for LC-MS analysis (e.g., protein extraction, fractionation, immuno-depletion, trypsin digestion, alkylation, reduction, etc.)
• Assist in generation and analysis of mass spectrometry (MS)-based proteomic data
• Follow standard operating protocols (SOP) in a CLIA/CAP laboratory environment including participating in annual competency and proficiency testing
• Collaborate effectively with an interdisciplinary team spanning expertise in medicine, biology, analytical chemistry, and statistics
• Maintain laboratory equipment, records, research results files, and databases
• Assist with written progress reports and development of standard operating protocols (SOPs)
• Assist with writing and co-authoring scientific manuscripts (in peer-reviewed journals)
• Work comfortably in a milestone-driven environment, with quarterly objectives
• Perform other duties as required

Qualifications

MINIMUM QUALIFICATIONS:

• Bachelor’s degree in a related scientific field or equivalent combination of education and experience
• 8 years of experience working in a lab outside of school coursework (or equivalent combination of advanced degree and work experience)
• Previous work maintaining mass spectrometry and HPLC instruments

PREFERRED QUALIFICATIONS:

• Master’s degree or higher in Protein Chemistry, Analytical Chemistry, Clinical Chemistry, Biochemistry , Molecular Biology or related discipline. Salary and title based on experience
• Exquisite attention to detail and the ability to adhere to standard operating protocols (SOP) and maintain records
• Excellent English writing and oral communication skills
• Proficiency with MS Office programs (Word, Powerpoint, Excel, and Access)
• Ability to multi-task efficiently in a highly interactive, interdisciplinary team environment
• Comfort in a milestone-driven environment, with quarterly objectives
• Willingness to learn new techniques
• Strong work ethic
• Previous experience in a CLIA/CAP or similar clinical lab environment
• Experience with LIMS, database software and proteomics tools
• Previous work with antibodies and peptide standards (immunoaffinity purification, immobilization on solid supports, screening hybridomas for mass spectrometry)
• Previous work in proteomics, genomics, and functional biology
• Previous experience with liquid handling robot usage and programming
• Ability to perform molecular biology and biochemistry experiments on human and animal biospecimens and cell lines

The annual base salary range for this position is from $78,894 to $118,310, and pay offered will be based on experience and qualifications.  

This position may be eligible for relocation assistance.

This position may be eligible for sign on bonus.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (12-22 days per year), paid sick leave (12-25 days per year), paid holidays (13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 6 months). 

Additional Information

Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world’s leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world’s deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems.

The Paulovich Lab at Fred Hutch (https://research.fredhutch.org/paulovich/en.html) is an interdisciplinary team whose mission is to develop and implement tools for protein quantification to enable precision medicine via patient selection and characterization of novel therapeutic targets. The lab has a major focus on mass spectrometry (MS)-based proteomics (both untargeted and targeted), as well as integrating proteomic data with genomic data. Our group is highly collaborative, participating in national and international consortia in which teams of scientists, statisticians, and clinicians work together to solve clinical or biological problems to impact human health.

This is a terrific opportunity within the Paulovich lab for a highly motivated and experienced full-time Staff Scientist to join our translational proteomics team to help drive translational projects forward towards clinical applications by performing bench-level experiments in support of proteomic, genomic, and transcriptomic analyses of clinical and preclinical biospecimens. The ideal candidate will be able to work as part of a team as well as independently to follow established standard operating protocols (SOP) in a CLIA/CAP laboratory environment.

Responsibilities

• Work with antibodies (immunoaffinity purification, immobilization on solid supports, ELISAs)
• Process proteomic samples for LC-MS analysis (e.g., protein extraction, fractionation, immuno-depletion, trypsin digestion, alkylation, reduction, etc.)
• Assist in generation and analysis of mass spectrometry (MS)-based proteomic data
• Follow standard operating protocols (SOP) in a CLIA/CAP laboratory environment including participating in annual competency and proficiency testing
• Collaborate effectively with an interdisciplinary team spanning expertise in medicine, biology, analytical chemistry, and statistics
• Maintain laboratory equipment, records, research results files, and databases
• Write progress reports and develop standard operating protocols (SOPs)
• Write and co-author scientific manuscripts (in peer-reviewed journals)
• Design and present Powerpoint presentations from results to colleagues and collaborators
• Work comfortably in a milestone-driven environment, with quarterly objectives
• Perform other duties as required

Qualifications

MINIMUM QUALIFICATIONS:

• Ph.D. degree in Protein Chemistry, Analytical Chemistry, Biochemistry, or related discipline
• Previous work maintaining mass spectrometry and HPLC instruments
• Staff Scientist position requires approval from the division Appointments and Promotions Committee depending on experience of the applicant

PREFERRED QUALIFICATIONS: 

• Exquisite attention to detail and the ability to adhere to standard operating protocols (SOP) and maintain records
• Excellent English writing and oral communication skills
• Proficiency with MS Office programs (Word, Powerpoint, Excel, and Access)
• Ability to multi-task efficiently in a highly interactive, interdisciplinary team environment
• Comfort in a milestone-driven environment, with quarterly objectives
• Willingness to learn new techniques
• Strong work ethic
• Previous experience in a CLIA/CAP or similar clinical lab environment
• Experience with LIMS, database software and proteomics tools
• Previous work with antibodies and peptide standards (immunoaffinity purification, immobilization on solid supports, screening hybridomas for mass spectrometry)
• Previous work in proteomics, genomics, and functional biology
• Previous experience with liquid handling robot usage and programming
• Ability to perform molecular biology and biochemistry experiments on human and animal biospecimens and cell lines

The annual base salary range for this position is from $82,118 to $185,016 and pay offered will be based on experience and qualifications. 

This position may be eligible for relocation assistance.

This position may be eligible for sign on bonus.  

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (up to 13 days per year), paid parental leave (up to 4 weeks), and partially paid sabbatical leave (up to 12 months for professor track faculty, up to 6 months for other scientific staff). 

Additional Information