Clinical Research Job Openings

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

The pediatric advanced practice provider (APP) provides care for pediatric blood and marrow transplant patients in both inpatient and outpatient setting under the supervision of the attending physician. The APP is responsible for the primary care of the patient to include assessment, triage and management of the transplant patient as part of a collaborative transplant team. Responsibilities include obtain medical history, perform physical examinations, review and order diagnostic studies, radiographs and prescribe treatments. APPs provide follow-up care of bone marrow donors under the supervision of attending physician. PALS certification is required for this position within 3 months of hiring date.

Qualifications

• Must be a graduate of a Physician Assistant  or Nurse Practitioner program (appropriate for care of Pediatric patients)
• Eligible for licensure in the State of Washington
• Have National Certification as appropriate for profession
• DEA licensure required
• Strong oral and written communication skills required
• EMR based computer skills and experience with CPOE preferred
• Strong team player with a can-do attitude is a must!  Ability to work as part of a multi-disciplinary team is essential.
• Must enjoy long-term relationships with patients undergoing intense therapy
• Pediatrics, Oncology or BMT experience preferred

Please include a cover letter when applying for this job that includes your specific interest in the Advanced Practice Provider position and working for Fred Hutchinson Cancer Research Center (either as an additional attachment on your profile or merged into the file that contains your resume.)

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Seattle Cancer Care Alliance is seeking a certified physician assistant (PA-C) or advanced registered nurse practitioner (ARNP) to provide an integrative medicine approach to the evaluation and medical management to Oncology and Hematology patients in the Seattle Cancer Care Alliance Integrative Medicine Program. The ARNP/PA-C will provide outpatient supportive care and integrative medicine services to a diverse patient population, will be an ambassador within and outside of SCCA as we continue to build this unique and innovative program. They will facilitate IM clinical research in this population. Integrative Medicine services may be offered from time of diagnosis to end of life. Integrative medicine therapies offered will focus on evidence-based symptom management, rather than cancer treatment, due to the available level of evidence at this time. Our vision is that an integrative medicine approach will become the standard of care for these patients.

The ARNP/PA-C will, within an integrative medicine framework, assess and manage basic health needs of patients, addresses treatment toxicities, perform integrative medicine procedures (e.g., acupressure, medical acupuncture), and consult with and refer to professional peers as needed. They will work collaboratively with the oncology treatment team to coordinate care of their patients. All clinical responsibilities are performed within the scope of practice, institutional privileges and under the supervision of an attending physician.

Responsibilities

Distinguishing Characteristics

The ARNP/PA-C at the SCCA functions within their scope of practice and collaborates effectively with other disciplines to provide state-of-the-art patient and family-centered integrative oncology care. 

• Training in a formal integrative medicine program is required and at least one year of experience in the use of integrative medicine therapies and selfcare in the oncology setting, including use of dietary supplements, mind-body medicine therapies, acupuncture, acupressure and other evidence based IM therapies as well as lifestyle practices that have been shown improved cancer outcomes.
• A working knowledge of basic oncology principles and practice.
• Excellent communication skills are necessary to ensure optimum patient care outcomes in a complex care environment.
• Respectful and ethical in their interactions with staff, patients and their family and caretakers alike.
• Skilled clinicians, providing evidence-based diagnosis and management of integrative medicine therapies related to the acute, symptomatic, and palliative care needs of patients with cancer.
• An effective educator teaching and providing information about disease processes, treatments, and management of treatment toxicities to patients, their family and other caregivers from an integrative medicine perspective.
• An effective educator of MD’s, APP’s ,RN’s, MA’s and all other supportive care professionals at SCCA in the basic principles and practice of supportive oncology care, palliative care and integrative medicine therapies and how they can add value to patient care. The APP in this role needs to teach and communicate an effective and practical way to incorporate integrative medicine approaches into the patient’s plan of care.

Scope of Work

• Takes responsibility for keeping up with current concepts in the management of patients in their care from an integrative medicine perspective.
• Performs complex and problem-focused H & Ps and assessments for patients.
• Evaluates and manages on-treatment and post-treatment side effects, as well as long-term surveillance and survivorship issues. Offers treatment recommendations from an integrative medicine perspective.
• Performs procedures according to licensure, credentialing, and scope of practice
• Collaborates and consults with other disciplines and services to ensure safe, effective, and timely treatment as well as continuity of patient care. Care will be coordinated in a multidisciplinary fashion with collaborating services which may include surgery, radiation oncology, medical oncology, medical nutrition, social work, physical therapy, spiritual health psychology, pain service, hospice, and palliative care. 
• Continuously works with medical and operations leadership to continue to build and enhance the Integrative Medicine service
• Participates in the conduct of cancer clinical research, including patient, caregiver, and peer education.
• Communicates changes in patient’s health status or urgent patient issues to the patient’s primary oncologist in a timely manner.
• Participates in patient rounds, conferences and committees
• Actively participates in the development and maintenance of patient management algorithms and standing orders.
• Documents patient care data in accordance with the SCCA and UWP policies
• ACLS certified
• Performs assessments of patient’s and caregivers’ knowledge, attitudes, and actions around the cancer diagnosis and treatment issues within an integrative medicine framework. Evaluates the physical and psychological state of the cancer patient.
• Provides psychological support to patients and their caregivers by participating in patient and/or family teaching, counseling and rehabilitation.
• Refers patients to community agencies and other resources to promote optimal adjustment and functioning in coordination with other SCCA supportive care services.
• Member of the Rapid Response team
• Other duties as assigned

Qualifications

Required qualifications

• Completion of a formal integrative medicine program such as:
  • Andrew Weil Center for Integrative Medicine-Integrative Medicine Fellowship
  • Integrative Oncology Scholars Program
• Licensure and credentialing:
  • Washington State Licensure as an ARNP or PA-C
  • Minimum of 2 years of experience as an ARNP or PA-C

Preferred qualifications

• Training in mind-body medicine therapies
• Training in medical acupuncture and/or auricular acupuncture
• Training in acupressure
• Experience in program development, educator mindset
• Comfortable speaking publicly (peers and patients)
• Experience as an Integrative Medicine Clinician

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The clinician works in the Lung Cancer Early Detection and Prevention Clinic (LCEDPC). The clinician will be responsible for patient intake, pre-clinic data evaluation, patient assessment, and follow-up. The clinician will coordinate the care of patients of this service in conjunction with the LCEDPC Director. Additionally, the clinician will interface with and assist with the CT Screening Program for Lung Cancer. All clinical responsibilities will be performed within the scope of practice, institutional privileges and under the supervision of the LCEDPC Director.

Responsibilities

• Evaluates 3-4 new patients in LCEDPC (staffing with attending) and up to 3 follow-ups (with or without attending staffing) each Wednesday (8 hours)
• Staff an independent LCEDPC follow-up clinic on a separate day from the main LCEPDC clinic to follow high-risk cases
• Prepares for LCEDPC by reviewing all cases prior to clinic (4 hours)
• Interfaces with pulmonary nurse, medical director, PCC team, wellness staff to ensure all visits are appropriately triaged, all appropriate images, reports and results are obtained (4 hours)
• Is the first contact for LCEDPC questions from other services, interfacing with medical director where appropriate (2 hours)
• Documents all nodule board summaries and communicates all results to patients, ordering follow-up imaging where appropriate (2 hours)
• Maintains 2 spreadsheets summarizing nodule tracking (2 hours)
• Maintains quality metrics for LCEDPC including patients seen, demographics and follow-up (1-2 hours)
• Assists with advanced bronchoscopy procedures performed at SCCA (Thursday morning, Tuesday afternoon prn) and at UW (possible additional afternoon/week) (4-8 hours)
• Meets biweekly with medical director to discuss clinical issues (30 minutes)
• Places all orders before and during LCEDPC (1 hour)
• Attends tumor board at UW (Tuesday afternoons, 1-2 hours)
• Provides cross-coverage to pulmonary consult service APP, when needed
• Provides cross-coverage and assistance to lung cancer screening service, when needed

Qualifications

• Graduate from an accredited PA or NP program.
• One year of ARNP or PA-C job experience
• Washington State and DEA licensure required
• ACLS training required
• Ability to work within a multidisciplinary team
• Proficiency with Excel and Word
• EMR experience required
• Strong oral and written communication skills

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

The pediatric advanced practice provider (APP) provides care for pediatric blood and marrow transplant patients in both inpatient and outpatient setting under the supervision of the attending physician.  The APP is responsible for the primary care of the patient to include assessment, triage and management of the transplant patient as part of a collaborative transplant team.  Responsibilities include obtain medical history, perform physical examinations, review and order diagnostic studies, radiographs and prescribe treatments.  APPs provide follow-up care of bone marrow donors under the supervision of attending physician.  PALS certification is required for this position within 3 months of hiring date.

Qualifications

• Must be a graduate of a Physician Assistant or Nurse Practitioner program (appropriate for care of Pediatric patients)
• Eligible for licensure in the State of Washington
• Have National Certification as appropriate for profession
• DEA licensure required
• Strong oral and written communication skills required
• EMR based computer skills and experience with CPOE preferred
• Strong team player with a can-do attitude is a must! Ability to work as part of a multi-disciplinary team is essential
• Must enjoy long-term relationships with patients undergoing intense therapy
• Pediatrics, Oncology or BMT experience preferred

Please include a cover letter when applying for this job that includes your specific interest in the Advanced Practice Provider position and working for Fred Hutch (either as an additional attachment on your profile or merged into the file that contains your resume.)

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

The Fred Hutchinson Cancer Research Center (Fred Hutch) and the University of Washington (UW) Department of Medicine, Division of Medical Oncology are jointly recruiting a full-time faculty member at the Research Associate/Acting Instructor level. This is a full-time, 12-month service period, annual appointment. The primary appointment will be in the Clinical Research Division of Fred Hutch.

The Fred Hutch, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation and immunotherapy, Fred Hutch and the UW provide a unique environment for conducting translational research and clinical care. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is a National Cancer Institute-designated comprehensive cancer center.

The selected individual for the advertised position is expected to participate in a year-long fellowship program with the goal of becoming an expert in blood and marrow transplantation (BMT) and immunotherapy (IMTX) services at Fred Hutch. The individual holding this position will rotate through outpatient and inpatient BMT (autologous and allogeneic, long-term follow-up) and IMTX services, and initially function as a primary care provider with increasing levels of patient care responsibility over the course of the year.  Approximately 8 months will be devoted to clinical activities with the remaining time available for the opportunity to participate in clinically focused research projects.  University of Washington faculty engage in teaching, research and service.

Anticipated start date would be July 1, 2021.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Clinical Research Coordinator will participate in the planning, coordination, and implementation of investigator-initiated and industry- sponsored clinical research studies for hematopoietic cell transplantation, with a focus on chronic graft versus host disease.

The incumbent is responsible for Investigational New Drug submissions, Institutional Review Board documentation, screening patients for eligibility, tracking patient visits, coordinating clinic procedures, and the collection, abstracting, reporting, and quality control of clinical trial data in accordance with protocols subject to FDA oversight. They are also for coordination of multi-site studies and the long-term follow-up activities associated with these protocols. Serve as a resource to other investigative trial sites to accomplish study goals.

This individual will work under the supervision of the Principal Investigator, will report regularly to the PI on study progress, and will be required to perform their responsibilities with a high level of independence within the scope of study protocol(s) and institutional guidelines. Uses judgment in data collection, quality control, liaison, and research coordination activities. Interacts with patients, physicians, and other clinical providers and support staff within and outside of the Fred Hutch / University of Washington / Seattle Cancer Care Alliance (SCCA) system including the SCCA Transplant Service.

Responsibilities

Responsibilities:

• Principal Investigator Support
• Serve as designee of the Principal Investigator (PI) to manage the daily clinical operations of assigned research studies in accordance with regulatory, GCP guidelines and institutional policy
• Assist the Principal Investigator (PI) with protocol development, revision, and study analysis
   

Enrollment

• Review study candidates’ medical records for study eligibility
• Ensure informed consent, initiate patient enrollment, and ensure accurate enrollment records are maintained
   

Education

• Educate clinical teams, ancillary departments, and patients to ensure safe and accurate protocol implementation
   

Protocol Implementation

• Develop and maintain tools for study implementation, which may include data collection tools, study reference materials, and study specific orders. Revise and utilize tools as necessary to fulfill the aims of the clinical trial.
• Initiate scheduling of patient clinic visits, and on-going study visits. Ensure clinical procedures, lab tests, and other protocol specific activities are completed as outlined in the protocols
• Complete requisition forms, assemble kits for upcoming research visits, transport laboratory samples, and ensure samples are processed and shipped according to study specific guidelines, while tracking and maintaining research supplies
• Collaborate with Investigational Drug Services (IDS) on drug assignment, dispensation information, and maintain regular communication regarding status of study subjects
• Ensure study drug self-administration and accountability with patients
  Administer study questionnaires
• Maintain appropriate source documentation, and complete or assist with accurate data entry into case report forms in a timely manner
• Coordinate monitoring visits and respond to queries and other requests from study monitors
  Identify and report adverse events in accordance with protocol, regulatory guidelines, and institutional policy
   

Budget & Billing

• Understand clinical trial budget and billing plans for patients enrolled on clinical trials.
• Work with internal partners to obtain and submit budget and billing information.
• Participate in the review of charges for patients on clinical trials to ensure billing compliance
   

Other Duties Which May Be Required

• Function as a protocol liaison with clinical teams, patients, and when necessary, other institutions or drug companies
• Maintain or assist in maintaining IRB correspondence and regulatory documentation.  Prepare or assist in preparing consent forms, continuation review reports, protocol modifications, and other study reports.
• Travel for industry sponsored investigator meetings, if interested
• Maintain thorough knowledge in the field through attending related project meetings and symposia, reading related literature, and maintaining professional associations

Qualifications

• Bachelor’s degree in life sciences required
• Minimum of 2 years of clinical research or related experience
• This position requires excellent organizational skills, attention to detail, ability to problem solve and to prioritize multiple competing tasks in a dynamic environment
• Collaborative focus is essential, as well as strong written and verbal communication skills, including computer skills
• Previous experience in oncology research and clinical data collection is preferred

Applicants must include a cover letter to be considered

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Antibody Research Group within the Clinical Research Division has an outstanding opportunity for a 60-75% FTE Clinical Research Nurse. The Clinical Research Nurse will participate in the planning, coordination, and implementation of clinical research studies involving innovative radioiummontherapy treatments for patients with hematologic malignancies. This position is currently funded for two years with the potential of becoming a regular position.

This individual will work under the supervision of the Principal Investigator (PI), and/or Lead Clinical Research Nurse, and will be required to perform his/her/their responsibilities with a high level of independence within the scope of study protocol(s) and institutional guidelines, and RN License Scope of Practice. This position will be part of a larger research team allowing for collegial support and cross coverage.

Responsibilities

NURSING DUTIES BY CATEGORY

Principal Investigator Support:

• Complete protocol specific nursing assessments for study participants with appropriate documentation in the medical record.
• Monitor lab results and outside medical records. Communicate clinically significant events to the PI and triage as necessary.
• May act as sub-investigator when the principal investigator designates protocol specific responsibilities to the research nurse that are within the research nurse scope of practice.

Collaboration:

• Identify trends in side effects and work with the principal investigator, the clinic nurse, Transplant Team and/or outside facilities to develop and evaluate patient management strategies.
• Collaborate professionally and regularly with clinic staff and research team members at UW, SCCA,sponsors and outside teams to provide seamless patient care for research participants.
• Interact with staff at outside facilities to ensure continuity of care for research participants as well as ensure protocol requirements are met. 
• Coordinate with PI, Clinic Nurses, & Pharmacists to manage side effects/adverse effects of study drugs with either concurrent medications or sponsor supplied study drugs.

Education:

• Provide protocol specific nursing education to study participants, caregivers, and colleagues.

Participation in Direct Patient Care at UWMC: 

• Fulfill requirements of UWMC and SCCA Credentialing.
• Perform clinical procedures such as blood draws from central line catheters and peripheral sites; evaluation of skin in suspected graft vs. host disease including skin biopsies; and other procedures within RN scope of practice as necessary.
• Administer medications, including study drugs, biologicals, and radioimmunoconjugates (with radiation safety training), according to protocol and within RN scope of practice.
• Assess patient and monitor for side effects to study drug with appropriate response including administration of PRN medications per protocol and, as necessary, consultation with PI or medical care team.

OTHER CLINICAL RESEARCH DUTIES BY CATEGORY

Principal Investigator Support:

• Serve as designee of the Principal Investigator (PI) to manage the daily clinical operations of assigned research studies in accordance with regulatory, GCP guidelines and institutional policy.
• Review study candidates’ medical records for study eligibility.

Enrollment

• Ensure informed consent, initiate patient enrollment, and ensure accurate enrollment records are maintained.

Education

• Educate clinical teams, ancillary departments, and patients to ensure safe and accurate protocol implementation.

Protocol Implementation

• Develop and maintain tools for study implementation, which may include data collection tools, study reference materials, and study specific orders. Revise and utilize tools as necessary to fulfill the aims of the clinical trial.
• Initiate scheduling of patient clinic visits, and on-going study visits. Ensure clinical procedures, lab test, and other protocol specific activities are completed as outlined in the protocols.
• Complete requisition forms, assemble kits for upcoming research visits, transport or arrange for transport of laboratory samples, and ensure samples are processed and shipped according to study specific guidelines, while tracking and maintaining research supplies.

Budget & Billing

• Understand clinical trial budget and billing plans for patients enrolled on clinical trials. Work with internal partners to obtain and submit budget and billing information.

Other Duties Which May Be Required

• Collaborate with Nuclear Medicine and/or Investigational Drug Services (IDS) on drug assignment and dispensation information, and maintain regular communication regarding status of study subjects.
• Function as a protocol liaison with clinical teams, patients, and when necessary, other institutions or drug companies.
• Maintain or assist in maintaining IRB correspondence and regulatory documentation. Prepare or assist in preparing consent forms, continuation review reports, protocol modifications, and other study reports.
• Maintain appropriate source documentation, and complete or assist with accurate data entry into case report forms in a timely manner.
• Coordinate monitoring visits and respond to queries and other requests from study monitors. Identify and report adverse events in accordance with protocol, regulatory guidelines, and institutional policy.
• Participate in the review of charges for patients on clinical trials to ensure billing compliance. Travel for industry sponsored investigator meetings.
• Maintain thorough knowledge in the field through attending related project meetings and symposia, reading related literature, and maintaining professional associations.

Other duties as assigned.

Qualifications

• Must have a Nursing degree and be a Licensed Registered Nurse in the State of Washington.
• Applicant must have a minimum of two years of nursing experience, with previous experience in hematology, oncology and/or research nursing preferred.
• This position requires excellent organizational skills, attention to detail, ability to problem solve and to prioritize multiple competing tasks in a dynamic environment.
• Strong candidates will have the ability to function independently and the flexibility to adapt to changes in treatment plans.
• Collaborative focus is essential, as well as strong written and verbal communication skills, including computer skills.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

The Fred Hutch Lung SPORE invites applications for an open full-time faculty position at the assistant, associate or full professor level on the Physician/Scientist pathway within the Clinical Research Division (CRD) of the Fred Hutchinson Cancer Research Center (Fred Hutch). We seek a laboratory-based scientist to conduct innovative, independent, and collaborative basic or translational research focused on lung cancer.

For consideration, the candidate must hold a PhD or MD (or foreign equivalent). Although most competitive applicants will have an established independently funded laboratory-based research program in lung cancer science, the committee will also consider applications at the assistant professor level. Pertinent research areas include (but are not limited to) molecular and genetic determinants of lung cancer initiation and progression, therapeutic resistance to targeted- and immune based therapies, tumor-initiating lung epithelial cell populations, and lung cancer early detection.

The Fred Hutch, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Fred Hutch, together with the University of Washington, Seattle Children’s, and the Seattle Cancer Care Alliance, is an NCI-designated Comprehensive Cancer Center with active training programs for graduate students and postdoctoral fellows. In addition, Fred Hutch has outstanding facilities and cutting-edge shared resources to support faculty success. Collaborative opportunities exist for joint and/or affiliate appointments in the Fred Hutch Divisions of Public Health Sciences, Human Biology, Basic Sciences, or Vaccine and Infectious Disease, as well as the University of Washington, depending upon candidate interest and qualifications.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion. 

Anticipated start date would be July 1, 2021.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Silberstein lab is recruiting a part-time Lab Aide to perform routine laboratory tasks in order to help support a lab under the supervision of the Principal Investigator. A commitment of at least two years is expected.

Please include a cover letter detailing your interest in this position and how it fits into your career plans. A cover letter is required for a completed application.

Responsibilities

• Murine colony Maintenance/PCR genotyping
• Re-stocking lab supplies
• Processing biohazard waste
• Making reagents

Qualifications

• A high school diploma or GED and current enrollment in college at the sophomore or higher level, with prior introductory biology and chemistry preferred but not required
• To be successful in this position, the lab aide must be detailed oriented, organized, capable of maintaining thorough records, and be able to work efficiently under supervision
• Attendance of lab meetings and involvement in a research project will be encouraged

The Fred Hutchinson Cancer Research Center (Fred Hutch) and the University of Washington (UW) Department of Pediatrics, Division of Hematology Oncology are jointly recruiting a full-time faculty member at the Research Associate/Acting Instructor level. This is a full-time, 12-month service period, annual appointment. The primary appointment will be in the Clinical Research Division of Fred Hutch.

The Fred Hutch, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation and immunotherapy, Fred Hutch and the UW provide a unique environment for conducting translational research and clinical care. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is a National Cancer Institute-designated comprehensive cancer center.

The selected individual for the advertised position is expected to participate in a year-long fellowship program with the goal of becoming an expert in bone marrow transplantation and Immunotherapy. This position will rotate through outpatient Hematopoietic Cell Transplantation (HCT) services (autologous and allogeneic transplant, immunotherapy, Long Term Follow Up) and on the inpatient transplant service initially as a primary care provider with increasing levels of independent patient care responsibility over the course of the year.  Exposure to some of our unique clinical programs, including non-malignant transplantation, high risk leukemia, and survivorship, will be part of the learning experience as well.  Approximately 75% of the year will be devoted to clinical activities with the remaining time available for the opportunity to participate in clinically focused research projects, which will be determined based on identification of mentors and projects. University of Washington faculty engage in teaching, research and service.

Anticipated start date would be July 1, 2021.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Bleakley laboratory in the Program in Immunology and the Clinical Research Division is looking for a highly motivated individual to support the development of immunotherapy for cancer.

Responsibilities

The post-doctoral research fellow will work on projects in the Bleakley Lab primarily on laboratory studies including, but not limited to, cancer antigen discovery, molecular cloning and evaluation of T cell receptors (TCRs) and transgene constructs in vitro and in vivo patient derived-xenograft models, and tracking T cell responses to cancer antigens in patient tissue samples.

The successful applicant will employ strategies such as functional T cell assays, cell culture, multi-parametric flow cytometry, flow sorting, DNA extraction for TCR sequencing, analysis of TCR sequencing data, isolation of cancer-specific T cells from human peripheral blood, experimentation in patient-derived xenografts, quantitative PCR and bioinformatics analysis.

This is a full-time position with a salary based on the NIH scale and excellent benefits.

Qualifications

Applicants will have a PhD in a biological science and/or a MD. The ideal candidate will have a research background in immunology with robust skills in molecular and cellular biology, including flow cytometry, T cell functional assays, DNA and RNA extraction, molecular cloning, PCR and quantitative PCR. Desirable skills include bioinformatics analysis, scientific writing and presentations.

To be successful in this position, the post-doctoral research fellow must be highly motivated with a track record of productive research, exemplified by first author publication(s) and presentations, and willing to work in a highly collaborative, fast paced, collaborative and dynamic environment. This position is suited to someone who enjoys mastering new skills, multitasking and working in a team science environment.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

The Hill Lab, in Seattle’s Fred Hutchinson Cancer Research Center Clinical Research Division, Program in Transplantation and Immunology, is recruiting a Post-Doctoral Research Fellow with expertise in transplantation and graft-versus-host disease. The candidate will contribute to an active research program, including studies of stem cell transplantation, focusing on gut graft-versus-host disease.  

Qualifications

• MD or PhD in a related field is required
• A strong foundation in molecular and cell biology
• Expertise in bone marrow/stem cell transplantation and graft-versus-host disease is strongly desired
• A track record of productive research

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

This position is in a laboratory in the Clinical Research Division and Human Biology Division that is developing new biologically active compounds as drugs and probes of pathways important to cancer and other diseases. The research effort involves interdisciplinary techniques ranging from cell and molecular biology to pharmacology to chemistry but requires experimental expertise in cell biology.

Responsibilities

• Play a major role in projects testing investigational compounds using in vitro and in vivo models.
• Design, execute and interpret experiments in cellular and molecular biology.
• Lead a leading drug evaluation project and assist other members of the lab as needed to carry out a drug evaluation project and assist other members of the lab as needed.
• help with preparation of figures for publication and writing and editing of manuscripts.

Qualifications

• A doctoral degree in molecular or cellular biology is required
• Expertise in tissue culture, molecular biology techniques including cloning, transfection/transduction and lentiviral production is required.
• Skills in mammalian cell culture and cell biology and/or pharmacology are desirable
• Computer skills (Mac, PC) are also highly desirable
• You must be able to work in a team environment with a significant degree of independence

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

A postdoctoral position is available immediately in the Grady lab at Fred Hutch. The applicant will perform data-driven research using state-of-the-art bioinformatics and computational biology tools across various research projects to advance translational research in epi/genomics of gastrointestinal cancers Adherence to principles of reproducible research, motivation to keep up with cutting-edge data analysis tools, and willingness to team-work in multi-disciplinary research programs will be vital to success in this position. The laboratory is situated in the Clinical Research Division at Fred Hutch.

Qualifications

Minimum qualifications:

• The successful candidate will have a PhD in bioinformatics, computational biology, or related field
• Established experience in analyzing data from RNA seq, genome-wide DNA methylation and multi-omics is desirable
• A track record of excellent first author publications is essential
• This position requires experience in managing computing servers, proficiency in computer languages including R/Bioconductor

Highly motivated candidates are encouraged to apply.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

A Post-Doctoral Research Fellow position is available with Dr. Anthony Rongvaux, Ph.D. at Fred Hutchinson Cancer Research Center. The Rongvaux Lab uses state of the art humanized murine models to study innate immune responses specific to the human species. This research project focuses on the fundamental mechanisms of innate immunity to HIV-1 infection.

Responsibilities

Over 35 million people are living with HIV-1 worldwide. About 40% of them don’t have access to antiretroviral therapies, resulting in over half a million deaths annually.

Acute HIV-1 infection induces a rapid inflammatory response, characterized by the production of large amounts of cytokines. However, this immune response is ineffective at controlling the virus. As a consequence, the virus can establish chronic infection and, if not treated, progresses to a lethal disease. Understanding why the natural immune response to HIV-1 infection does not confer protection, but rather contributes to pathogenesis, could help us design more effective therapies and vaccine strategies.

Using state of the art humanized murine models, single-cell RNA sequencing and genome editing, the postdoctoral fellow will study the mechanisms by which the immune system detects, and responds to infected cells. This work will result in a better understanding of the contribution of the innate immune system, in vivo, to antiviral activity vs. immune dysfunction and pathogenesis.

Qualifications

Applicants will have a recent PhD in Immunology, Virology, Molecular Biology or a closely related field

The ideal candidate will have a strong background in HIV-1 research and/or in immunology with robust skills in molecular and cellular biology. Desirable skills include animal studies and bioinformatics analysis.

To be successful in this position, the post-doctoral research fellow must be highly motivated with a track record of productive research, exemplified by at least one first author publication(s), and willing to work in a highly collaborative, fast paced, collaborative and dynamic environment. This positions is suited to someone who enjoys mastering new skills, and working in a multidisciplinary team environment.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

A highly qualified and motivated postdoctoral fellow is sought to join the laboratory of Dr. James Olson in the Clinical Research Division at the Fred Hutchinson Cancer Research Center. The focus of research conducted in our group is the discovery and advancement of novel therapeutic biologics to treat pediatric brain cancer along with other central and peripheral diseases. To enable this discovery of novel treatments, we utilize cutting edge protein expression platforms, predictive assays, advanced efficacy models, and state of the art resources.

The incumbent will play a key role in progressing our tunable hydrogel technology program for pediatric brain tumors, as wells as in developing their own complementary research in discovering best methods of local delivery of therapeutic biologics. The successful candidate will join our highly innovative team to develop expertise in the local delivery of therapeutic molecules with both anti-cancer and immune-stimulatory activities. Responsibilities will include development of novel hydrogel and linker chemistries to optimize and tune the release of therapeutic payloads, optimization of in vitro and in vivo xenograft models to assess therapeutic activity and application of immunohistology, and development of additional ex vivo techniques to further characterize the effects of local delivery. The successful applicant will be expected to leverage their own expertise and the resources available at Fred Hutch to perform cutting edge scientific research. With the end goal of becoming a successful, independent researcher, they will engage with their colleagues to develop innovative approaches to the delivery of therapeutics with potential translation into the clinic. This position will require contributions both as an individual and as part of a larger team, as well as supervision of junior scientists. The incumbent will work closely with other members of the Hydrogel Technology team and interface with protein sciences, chemistry, and pharmacology to achieve the goals of the program. The Olson Lab has broad expertise in oncology, in vivo pharmacology, protein therapeutics, and clinical translation, and provides a vibrant research environment for career advancement toward top-tier positions.

Qualifications

To be considered for this position, the successful candidate must have:

• A recent PhD or equivalent advanced degree, ideally in the areas of cellular biology, pharmacology, pathology, or a related field
• Previous experience in biologics, therapeutic proteins, and advanced delivery systems
• Experience with advanced biochemistry techniques to create novel delivery systems for anti-cancer therapeutics
• Understanding of the drug discovery process (desired)

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

A highly qualified and motivated post-doctoral research fellow is sought to join the laboratory of Dr. Sunil Hingorani at Fred Hutchinson Cancer Research Center in Seattle, WA.

Our laboratory investigates molecular and cellular mechanisms of pancreatic ductal adenocarcinoma (PDA) pathogenesis.  The murine models of distinct genetic subtypes of pancreas cancer that we have developed form the basis of our integrated, systematic, and multidisciplinary research program.  Our efforts are directed at identifying and overcoming stromal barriers to treatment (including elevated interstitial pressures, activated fibroblasts, and multiple mechanisms of immune suppression); identifying and disrupting molecular drivers of metastasis; and developing immune-based strategies.  Our ultimate aim is to reduce our discoveries to practice in the clinic in order to radically transform the approach and prognosis for patients with this devastating disease.

Qualifications

Successful applicants will have:

• A Ph.D. in the field of molecular biology, biomedical engineering, biochemistry, biophysics, cancer biology, immunology or genetics
• Experience with standard molecular and cellular biology techniques
• A demonstrated track record of productive research
• Experience with generation and characterization of genetically engineered murine models, advanced imaging techniques, and/or gene targeting is highly desired
• Ability to develop create approaches to experimental design
• Ability to work both independently and as part of a laboratory team

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. Fred Hutchinson Cancer Research Center (Fred Hutch), home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, Fred Hutch’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Walter Laboratory in the Clinical Research Division is recruiting an outstanding postdoctoral research fellow to work as part of a team investigating new treatments for patients with acute myeloid leukemia (AML) primarily focused on improving existing, and developing novel, antibody-based immunotherapies, and rendering them safer for clinical application. Current projects include preclinical drug development/testing (in part with academic and industry partners), studies on mechanisms of action and resistance of antibody-based therapeutics and identification of strategies to overcome these limitations, and development of approaches to protect normal tissues from the toxicities of AML-targeted therapies (e.g. via use of genome editing).

Responsibilities

The newly hired fellow will work under the direction of the Principal Investigator and senior laboratory personnel and will be involved in the following techniques/duties:

• Generation of recombinant antibodies and other protein therapeutics via transient and permanent expression systems
• Conduct of immunization strategies to raise new antibodies
• Generation of engineered/gene-edited human leukemia cells
• Tissue culture of mammalian cell lines and patient-derived primary human cells
• Antibody drug conjugate (ADC) cytotoxicity, antibody-dependent cellular cytotoxicity, T-cell and NK-cell cytotoxicity assays
• Flow cytometry-based immunophenotyping, FACS isolation of mammalian cells
• Purification, cloning, and manipulation of RNA, cDNA and genomic DNA
• PCR and RT-PCR, including quantitative assays using qPCR
• Lentiviral vector modification, lentiviral particle preps and viral transduction
• Protein gels, immunoprecipitation, western blotting, immunofluorescence microscopy
• General laboratory duties and maintenance of laboratory equipment

Qualifications

Required qualifications:

• A recent PhD in a relevant field of biology such as immunology, cell and molecular biology, genetics, biochemistry, pathology, bioinformatics, or genome sciences
• Ability to drive an individual project but also be highly collaborative with academic and industrial partners
• Ability to work independently and with scientific rigor
• Interest in academic career and applying for independent funding support
   

To be successful in this position, the postdoctoral research fellow must be organized, clear and concise in their communication, enthusiastic, a team player, and have a desire to establish a career as a future independent investigator. Fellowship opportunities are available through several philanthropic and government organizations; fellow will have administrative support for the application process.

Applicants must include:

• Cover letter discussing your interest in this position, research interests and career goals
• Curriculum Vitae
• Contact information for three references

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

A Postdoctoral Research Fellow position is available immediately to join the laboratory of Scott N. Furlan in the Clinical Research Division of the Fred Hutchinson Cancer Research Center in the newly refurbished Steam Plant building. The postdoctoral fellow will join an ongoing project to study the biology of Ewing sarcoma metastasis using cutting-edge, single cell genomics. The successful applicant will utilize standard techniques of genomics, cellular and molecular biology. 

Qualifications

Suitable applicants should have a Ph.D. degree in genetics, tumor biology or a closely-related field. The candidate must have a strong knowledge of next-generation sequencing, tissue culture, and computational biology. Preferred qualifications include experience with CRISPR/Cas9 gene editing and proteomic techniques. The successful candidate will be a scientifically driven, well-organized self-starter.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The post-doctoral research fellow will work on independent and collaborative projects in Dr. Chapuis' laboratory developing adoptive T cell immunotherapy within the Program in Immunology and Clinical Research Division at Fred Hutchinson Cancer Research Center. This highly translational research will involve the development of novel TCR-based cellular therapies for clinical translation; development of next-generation humanized murine models to gain insights into the in vivo barriers to effective therapy; and may include monitoring patients through-out the course of treatment with T cell therapies.  Additionally, the successful applicant will employ strategies for improving current immunotherapy treatments, including and not limited to; cloning and characterizing T cell receptors (TCRs) specific for cancer-associated antigens, developing cutting-edge strategies for genetic modification of human T cells including CRISPR-based gene editing, and developing/testing new approaches for overcoming immunosuppressive signals in the tumor microenvironment.

Dr. Chapuis is a leader in the development and clinical application of adoptive immunotherapy using genetically modified T cells and is committed to the advancement of this approach. This is a full-time position with a salary based on the NIH scale and excellent benefits.

Responsibilities

• Cell Culture, cell sorting, flow cytometry, intracellular staining, and transfections
• Molecular bench work with PCR, cloning, and vector design
• NGS including, Single cell RNA sequencing, WEX, WGS
• Validation through functional and killing assays
• Write and submit grants and first author papers to peer reviewed journals
• Stay current with relevant publications and apply knowledge to research
• Compile data and synthesize innovative problem-solving methods
• Collaborate and present data with a wide range of stakeholders and partners
• Train others on protocols
• Mentor and lead undergraduate and graduate students
• Assist with lab maintenance and function

Qualifications

Minimum qualifications

• MD and/or a PhD in a biological science with a diverse knowledge of immunology
• Proficient in immunology technique and knowhow
• Strong scientific writing skills, ability to write and apply for funding opportunities and abstracts
• Able to digest complex material and synthesize innovative ideas
• Compile and clearly present data to an eclectic audience, both orally and written
• Well versed in flow cytometry

Preferred qualifications

• Experience with molecular techniques lentiviral modification of T cells
• Experience in analysis of TCR signaling pathways and T cell function
• Experience with in vivo murine experimentation
• Familiarity with biostatistics, R and Python languages
• Ability to derive and maintain T cell tissue cultures
• Have a good understanding of SRAs and/or phase I/II clinical trials

To be successful, the post-doctoral research fellow must be: highly motivated and driven, able to work independently and with others, be open to receive and provide feedback for scientific discussion and general lab work, possess an acute attention to detail and organizational skills, think critically and problem solve and be excellent at note taking and reproducibility.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Program in Transplantation Biology in the Clinical Research Division is seeking an incumbent to assist in research monitoring for the myeloablative and non-myeloablative transplant program.

The Program Assistant will work under the supervision of the Principal Investigators and Research Staff Manager to assist in data entry, specimen tracking, document review, patient outcome assessment and regulatory support for a wide variety of transplant protocols.

Responsibilities

• Review patient records and update patient database
• Assist in coordination of patient disease restaging, research specimens, and appointments with the SCCA, Long Term Follow-Up Department, Seattle Children’s, and local physicians
• Assist with outside center support
• Deliver documents, kits, and other research support items between campus buildings
• Case report form data entry
• Serve as a resource for data projects using Access
• Assist with regulatory support
• Perform other duties, as assigned

Qualifications

• A bachelor’s degree and a minimum of one year experience in a support role in a medical, scientific, or research setting is required. (The equivalent combination of education and experience is acceptable.)
• Strong attention to detail and excellent organizational and communication skills are essential
• Must work well in a team-oriented environment
• To be successful in this position, the program assistant must be able to provide consistency across complex documents
• Must be highly proficient using Microsoft Word and Excel, proficiency with ACCESS highly desirable
• Must be able to handle a high-volume work load

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

A Clinical Research Division laboratory that studies hematopoietic stem cell and T cell biology and develops novel gene therapy and gene editing strategies is recruiting a postdoctoral fellow or research associate to participate in preclinical and in vivo studies.

Responsibilities

The position involves additional responsibilities, such as:

• Development of immunological assays, processing of primary tissue samples, and culture/analysis of cells infected with HIV and related viruses.
• The candidate will study and develop methods to characterize immune responses against gene and cell therapy products, and will work under the PI and other senior members of the research team.
• The candidate will be expected to work closely within a diverse team of bench scientists, graduate students, and post-graduate team leaders, and publish and present their work in both internal and external events.

Qualifications

• A PhD or MD in a scientific field is required. 
• The individual must possess knowledge of advanced immunology assays, including extensive multi color flow cytometry experience. 
• Previous experience in infectious and/or genetic diseases, and a background in hematopoietic stem cell and/or T cell biology are highly desired.
• Cellular immunology experience required.
• Experience is preferred in one or more of the following areas: hematopoietic stem cell cultures/model systems, chimeric antigen receptor (CAR) T cell manufacturing, in vivo studies, flow-assisted cell sorting, and/or molecular biology techniques e.g. quantitative PCR and plasmid cloning.
• Previous experience in gene therapy/gene editing, and/or basic bioinformatics is desired, but not required.
• To be successful in this position, the candidate must be highly motivated and able to work independently to design and execute experiments, possess a high level of initiative and attention to detail, and must also be able to multi-task and prioritize a diverse experimental portfolio.
• The candidate must also be capable of working independently in a team environment.
• Candidates with excellent organizational skills and communication skills (written and oral) are encouraged to apply.
• A cover letter, including a research statement is required.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Hingorani Laboratory investigates molecular and cellular mechanisms of pancreatic ductal adenocarcinoma (PDA) pathogenesis. The murine models of distinct genetic subtypes of pancreas cancer that we have developed form the basis of our integrated, systematic, and multidisciplinary research program. Our efforts are directed at identifying and overcoming stromal barriers to treatment (including elevated interstitial pressures, activated fibroblasts, and multiple mechanisms of immune suppression); identifying and disrupting molecular drivers of metastasis; and developing immune-based treatment strategies. Our ultimate aim is to take our discoveries and reduce them to practice in the clinic in order to radically transform the approach and prognosis for patients with this devastating disease.

This position represents an excellent opportunity for a highly motivated individual with a passion for science to work and learn in a dynamic scientific environment while addressing important problems relevant for the successful treatment of cancer.

Responsibilities

The histotechnician will:

• Establish and optimize histochemical, immunohistochemical and immunofluorescence procedures for a team of pancreas cancer researchers. 
• They will be involved in all steps of these procedures including fixation and embedding of tissues, sectioning, staining, analyses and presentation of findings.
• This person will be responsible for the overall histopathology operations of the laboratory, ordering reagents and supplies, maintaining inventories, and preparing solutions, stains, and reagents necessary for various histology protocols.
• The histotechnician will also maintain the state-of-the-art equipment used within histology, including processors, microtomes and autostainers.

Qualifications

• A bachelor’s degree in a biological science is strongly preferred, and a minimum of one year of experience as a histology technician is required. 
• Previous experience with antibody “cocktailing” and IHC/IF multiplexing is advantageous.
• Strong troubleshooting skills and the ability to multi-task with precise attention to detail is especially critical. 
• To be successful in this position, the applicant must be capable of taking initiative, have precise attention to detail, and be able to work independently.
• Certification by a nationally recognized agency, such as the American Society of Clinical Pathology, is preferred. 

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Silberstein lab is seeking to recruit a Research Technician I.

The main goal of the laboratory is to combine basic stem cell biology and clinically relevant murine models in order to develop new therapeutic approaches to promote hematopoietic stem cell function in bone marrow failure and to enhance hematopoietic reconstitution after bone marrow transplantation. We are particularly interested in using microenvironment-derived molecules as drugs or therapeutic targets, and have identified several novel niche factors using proximity-based single cell analysis as a discovery strategy (for details, please see Silberstein et al, Cell Stem Cell 2016, Goncalves, Silberstein et al, Cell 2016).

Please include a cover letter detailing your interest with your application.

Responsibilities

A successful candidate will work as a part of the highly collaborative team and focus on conducting animal experiments which involve stem cell transplantation, fluorescently-activated cell sorting/analysis and molecular studies of stem cells/progenitors. They will also share responsibility for murine colony maintenance.

The incumbent will be part of a Stem Cell and Gene Therapy Program at the Fred Hutch and interact closely with other laboratories within the Program (Kiem, Adair, Bernstein, Hadland, Doulakov) and those within Integrated Immunotherapy Research Center (Dudakov, Turtle).

Qualifications

Required qualifications:

• This position requires a bachelor's degree in a biological science and some research experience or laboratory knowledge. Must have scientific knowledge in the area of study and basic laboratory skills. Independent research experience in addition to school lab experience is usually necessary.
• Strong interest in stem cell research/bone marrow disorders.
• Excellent written and verbal communication skills.
• To be successful in this position, the technician must be highly motivated, have a high level of initiative, work carefully, and keep detailed records. They must also be capable of working independently in a teamwork environment and have excellent interpersonal and communication skills.
• A short cover letter explaining why a candidate has chosen to apply to the position.

Preferred qualifications:

• Previous experience of working with murine models is not essential, but one of the chief responsibilities will involve handling the animals daily and performing standard procedures.
• Some multi-parameter flow cytometry experience (undergraduate research or post graduation).
• Candidates considering medical/graduate schools are encouraged to apply.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

The Program in Immunology within the Clinical Research Division is looking to hire a research technician who will independently as well as collaboratively help with the murine husbandry, as well as enrolling murine in mock studies using multiple murine techniques.

Responsibilities

The candidate will perform numerous cellular and molecular techniques including, but not limited to, DNA extraction and PCR for genotyping and flow cytometry for phenotyping. 

An ideal candidate would be detail-oriented with experience in pre-clinical procedures, experiments and data collection, have a proven track record in handling conventional and genetically engineered animals, and be able to perform both in a collaborative, multidisciplinary environment as well as independently, with a desire to build relationships and promote synergy.

Skills:

• Data collection and Documentation
• Independent murine handling experience
• Perform Murine colony management
• IVIS imaging
• Ultrasound imaging
• Routine drug administration via IV, RO, IP, SQ and well as oral gavage
• Blood collection via retro-orbital
• Sterile tissue collection
• Experimental preparation
• Molecular biology (DNA isolation, PCR, Gel electrophoresis)
• 6-color flow cytometry experience
• Communication and planning with research personnel and principal researchers
• Maintenance of experimental records

Qualifications

• BA/BS in a scientific field required
• Two years or more of post-bachelor’s laboratory research experience.
• Must have scientific knowledge in the area of study and basic laboratory skills
• The candidate should have extensive mouse handling experience, including: independent breeding, weaning, ear tagging, intraperitoneal and subcutaneous injections, oral gavages, retroorbital bleeding, IVIS imaging, ultrasound imaging, murine necropsies, and T cell isolation from tumors
• Independent research experience in addition to school lab experience is usually necessary

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here. 
 
At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion. 
 
A Research Technician’s position is available immediately in the Clinical Research Division of the Fred Hutchinson Cancer Research Center (FHCRC), Seattle, WA.  The successful applicant will work with Dr. Matthias Stephan, M.D., Ph.D. to explore the fast-developing and highly interdisciplinary field of immunobioengineering (https://www.nature.com/articles/s41467-020-19486-2). Using next-generation immunomodulatory synthetic materials, the Research Technician will help develop new approaches beyond existing T-cell-based therapies to therapeutically manipulate the immune system against cancer (https://www.nature.com/magazine-assets/d41586-017-08701-8/d41586-017-08701-8.pdf). 

Responsibilities

The Research Technician II is responsible for performing standard and investigative laboratory work in support of scientific research by performing bench-level experiments, operating analytical instruments, recovering, compiling and verifying the accuracy of research data; performing calculations; preparing charts, graphs and summaries.  
 
Responsibilities include:

• Perform experiments at the bench level to support investigative work. Prepare and maintain laboratory reagents, stocks, cultures or cell lines. Perform and modify documented protocols and assays. Maintain laboratory records and compile data on experiments and assays. 
• Interpret and report on experimental results. Perform statistical analysis of test results and prepare written reports on work performed 
• Identify methodological problems in research protocol and implement modifications to optimize experimental results 
• Prepare and present written or oral progress reports concerning studies including assembly, organization, and interpretation of data 
• Assist in the design of experiments; may be responsible for the performance of individual research projects 
• Conduct literature reviews to assist in determining most suitable methods to be used in research 
• Assist in publication of results by proofreading, editing, and contributing ideas 
• May perform statistical analyses, write computer programs, or manage research data base 

The Research Technician III Performs the duties of the Research Technician II plus:

• May lead or supervise other laboratory personnel and be responsible for the daily operation of the laboratory. 
• Collaborate with primary investigator and assist in designing experiments; examine proposals to determine projects and methodologies best suited to research objectives and the overall goals of the laboratory. 
• Summarize and write for publication or presentation the results of research projects, often as co-author or author.  Edit and write reports of research. 
• Consult with the Principal Investigator and others in the scientific community on problems and related projects. 
• Determine the most suitable methods to be used in research; determine appropriate experimental controls. 
• Conduct literature reviews to assist in determining most suitable methods to be used in research. 

Qualifications

• BS or MS in the areas of immunology, cell biology, biochemistry or related field.  
• Intermediate level position requiring 2 years previous experience working in a laboratory 
• Independent research experience outside of laboratory course work is usually necessary 
• The Research Technician III position is a senior level position requiring extensive experience in a laboratory. Generally, the incumbent will possess a master's degree in a related scientific field.  
• Excellent knowledge of multi-color and intracellular flow cytometry, and data analysis using FlowJo software desired. 
• Strong proficiency in the development and execution of cell-based assays for immune cell function (T-cell proliferation, cytokine release, and cytotoxicity assays) with murine and human primary T cells is required.  

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists. 

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

A Clinical Research Division laboratory, Kiem Lab, that studies hematopoietic stem cell and T cell biology is recruiting a Research Technician II/III to participate in projects focused on novel gene therapy and gene editing strategies for HIV cure.  Using established preclinical and in vivo models of HIV persistence, the technician will optimize and perform diverse immunological assays, process primary tissue samples, and participate in novel assay development. Although the position will focus primarily on samples infected with HIV and related viruses, applying similar approaches for other diseases and pathologies will also be explored. The technician will work under the PI and a senior member of the laboratory, within a diverse team of technicians, graduate students, and post-graduate researchers.

Qualifications

• Bachelor’s degree required. A Master’s or equivalent degree is preferred.
  • Research Technician II minimum qualifications - Intermediate level position requiring at least 3 years previous experience working in a laboratory and BA/BS. Independent research experience outside of laboratory course work is usually necessary.
  • Research Technician III minimum qualifications- Senior level position requiring extensive experience in a laboratory.  Generally, the incumbent will possess a Master's degree in a related scientific field.
• The individual must have experience with multicolor flow cytometry
• Previous experience in infectious and/or genetic diseases, and a background in hematopoietic stem cell and/or T cell biology are highly desired
• Experience is preferred in one or more of the following areas: hematopoietic stem cell cultures/model systems, chimeric antigen receptor (CAR) T cell manufacturing, in vivo studies, flow-assisted cell sorting, and/or molecular biology techniques e.g. quantitative PCR and plasmid cloning.
• Previous experience in gene therapy/gene editing, and/or basic bioinformatics is desired, but not required.

To be successful in this position, the candidate must be highly motivated and able to work independently to design and execute experiments, possess a high level of initiative and attention to detail, and must also be able to multi-task. Candidates with excellent organizational skills and communication skills (written and oral) are encouraged to apply.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here. 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.
 

The Geraghty Lab seeks an exceptionally skilled, experienced molecular biologist to join their team. A summary of Dr. Geraghty's research can be found here.

Responsibilities

The Staff Scientist will work in a research laboratory that performs state of the art genotyping for disease association studies.  The laboratory collaborates with local and international labs to carry out anthropological, clinical, and basic disease studies that are aimed at a better understanding and development of data and tools for diagnosis and treatment of a variety of human diseases. 

A core goal is to facilitate the use of immune genetic data both as a predictive tool in anticipating clinical outcomes (diagnosis) and as knowledge and information relevant to the biological processes causal of those outcomes (therapeutics.) Precisely such application has long been active in support of hematopoietic cell transplants (HCTs) and plans are to expand and extend use to infectious disease, autoimmunity, and cancer.  This work includes two fronts in expanding the genetic testing capacities of our genotyping systems and developing new analytic capabilities for data application. Novel typing systems focusing on heretofore untested immune response variation are being developed by building on the core systems supporting HLA. For novel analytics, study cohorts have been assembled to apply machine learning/artificial intelligence tools to identify patterns of immune genetic variation predictive of clinical outcomes in HCTs (for replication with and extension with new methods and added data) and for COVID-19 as a model of infectious disease.

Qualifications

A PhD in a biological science or related with an understanding of the fundamentals of molecular genetics is required. Familiarity with the genetics of the immune response would be a significant advantage – in particular with the HLA system. To be successful in this position, one must have the ability to communicate effectively with coworkers, working together in executing tasks that engage multiple complementary activities in parallel. In addition to benchwork, these activities include data analysis and effective interaction with the laboratory’s software and data analysis group. The ability and willingness to take initiative in problem solving and suggestions for workflow improvements will be a key to advancement and associated benefits.  

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Responsibilities

A Staff Scientist position is available immediately to join the laboratory of Scott N. Furlan in the Clinical Research Division of the Fred Hutchinson Cancer Research Center in the newly refurbished Steam Plant building. The successful applicant will join an ongoing project to study the biology of Ewing sarcoma metastasis using cutting-edge, single cell genomics. The successful applicant will utilize standard techniques of genomics, cellular and molecular biology.

Responsibilities for this highly skilled laboratory scientist will include designing, performing and analyzing experiments, troubleshooting technical issues and mentoring junior lab members. The successful candidate will also be expected to contribute to the preparation of manuscripts and grant proposals and oversee large programs that include collaborating laboratories.

Qualifications

Applicants should be highly motivated scientists, with a MD and/or PhD degree in Genetics or Oncology. Four or more years of post-Ph.D. laboratory experience preferred, however we will consider those who are newly graduated with their Ph.D. An ideal candidate will have a working knowledge of cancer biology, and experience with next-generation sequencing approaches and computational biology. A track record of high impact publications and early success in grant applications is expected.

Interpersonal skills should include:

• excellent organizational skills
• attention to detail and reliable record-keeping
• ability to design and execute protocols and work independently including experimental troubleshooting
• effective communication and interpersonal skills for working with other lab members and productive interactions with collaborators

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.

Clinical Biostatistics is seeking a statistical research associate (SRA) to support studies conducted within the Clinical Research Division (CRD) of Fred Hutch. The Clinical Biostatistics department is composed of 6 faculty members, 4 SRAs, and 5 programmers/data managers. The group conducts collaborative statistical research related to clinical research projects for Fred Hutch / UW Consortium members. In collaboration with CRD principal investigators, the department is responsible for the design and analysis of Phase I, II and III clinical trials and the analysis of data from observational studies related to hematopoietic cell transplantation (HCT) and solid tumor research.

Responsibilities

This position will work closely with a PI and research team from CRD on studies focused on chronic graft-versus-host disease (GVHD) and long-term follow-up research after HCT. Responsibilities will include study design, creation of data-cleaning programs, primary and secondary analyses of clinical, epidemiological, and high-dimensional molecular data, and sample identification from the biorepository based on clinical characteristics. Participating centers are located in the US and Canada, and studies are funded by NIH. This position will also involve collaboration with studies conducted by the breast cancer group within the CRD and Fred Hutch / UW Consortium, providing analyses of clinical and high-dimensional molecular data. The successful candidate will be supervised and supported by the faculty and programming staff within Clinical Biostatistics, but will be expected to be able to work independently, grasp the biologic fundamentals of the target diseases, and enjoy being a key member of a very active research consortium.

Qualifications

• MS in Statistics or Biostatistics required
• Experience working in the biomedical field
• Competency with SAS and R; familiarity with other statistical software packages (i.e., Stata) preferred
• Strong programming skills required
• Demonstrated strong communication and interpersonal skills as well as ability to juggle multiple projects required
• Must be able to clearly convey complicated statistical concepts to non-quantitative scientists
• Strong writing skills required
• Must be able to work independently and with a diverse group of people

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and anti-racism in your career or that will be made through work at Fred Hutch is requested of all finalists.