Clinical Research Job Openings

Hematopoietic Cell Transplant (HCT) and Immunotherapy (IMTX) Programs

The Fred Hutchinson Cancer Research Center (Fred Hutch) and the University of Washington (UW) Department of Medicine are jointly recruiting a full-time faculty member at the Assistant Member/Assistant Professor or Associate Member/Associate Professor level without tenure due to funding (WOT), commensurate with experience, in the Clinical Research Division of the Fred Hutch and the Division of Medical Oncology, Department of Medicine at the UW. This position has an annual service period of 12 months [July 1-June 30].  The Fred Hutch, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation and immunotherapy, Fred Hutch and the UW provide a unique environment for conducting translational research and clinical care. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is a National Cancer Institute-designated comprehensive cancer center.

The primary appointment will be in the Clinical Research Division of Fred Hutch. The selected individual for the advertised position is expected to enhance our clinical care and clinical research programs in hematopoietic cell transplantation and immunotherapy. All clinical research interests will be considered however, there is a particular interest in applicants with demonstrated experience in the field of immunotherapy. Applicants with extensive research experience will also be considered. University of Washington faculty engage in teaching, research and service.

Anticipated start date January 2, 2019

The Fred Hutchinson Cancer Research Center (Fred Hutch) and the University of Washington (UW) Department of Medicine, Division of Medical Oncology, are jointly recruiting a full-time faculty member at the Assistant or Associate Professor level without tenure due to funding (WOT), commensurate with experience, in the Clinical Research Division of the Fred Hutch and the Division of Medical Oncology, Department of Medicine at the UW. This position has an annual service period of 12 months [July 1-June 30]. The primary appointment will be in the Clinical Research Division of Fred Hutch. The successful candidate will be a thought leader in the field of hematopoietic cell transplantation who is engaged in innovative laboratory-based research investigating the mechanisms of transplant complications and/or relapse after transplantation. The selected individual for the advertised position is also expected to provide clinical care and enhance our clinical care programs in the hematopoietic cell transplant and immunotherapy programs. Fred Hutch and University of Washington faculty engage in teaching, research and service.

The Fred Hutch, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation and immunotherapy, Fred Hutch and the UW provide a unique environment for conducting translational research and clinical care. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is a National Cancer Institute-designated comprehensive cancer center.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion. 

Anticipated start date would be July 1, 2021.

The Fred Hutchinson Cancer Research Center (Fred Hutch) and the University of Washington (UW) Department of Medicine, Division of Medical Oncology are jointly recruiting a full-time faculty member at the Research Associate/Acting Instructor level. This is a full-time, 12-month service period, annual appointment. The primary appointment will be in the Clinical Research Division of Fred Hutch.

The Fred Hutch, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation and immunotherapy, Fred Hutch and the UW provide a unique environment for conducting translational research and clinical care. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is a National Cancer Institute-designated comprehensive cancer center.

The selected individual for the advertised position is expected to participate in a year-long fellowship program with the goal of becoming an expert in blood and marrow transplantation (BMT) and immunotherapy (IMTX) services at Fred Hutch. The individual holding this position will rotate through outpatient and inpatient BMT (autologous and allogeneic, long-term follow-up) and IMTX services, and initially function as a primary care provider with increasing levels of patient care responsibility over the course of the year.  Approximately 8 months will be devoted to clinical activities with the remaining time available for the opportunity to participate in clinically focused research projects.  University of Washington faculty engage in teaching, research and service.

Anticipated start date would be July 1, 2021.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

We are looking for a Clinical Research Coordinator to join our dynamic team of dedicated and skilled research staff working on clinical trials in the field of hematologic malignancies. The Clinical Research Coordinator will participate in the planning, coordination, and implementation of multiple clinical trials involving human subjects. The focus of this position will be on coordinating trials run through the National Cancer Institute’s (NCI) National Clinical Trial Network (NCTN).

This individual will work under the supervision of the Clinical Program Operations Director and will be required to perform responsibilities with a high level of independence within the scope of study protocol(s) and institutional guidelines.

Responsibilities

• Serve as designee of the Principal Investigator (PI) to manage the daily clinical operations of assigned research studies in accordance with regulatory, GCP guidelines and institutional policy.
• Review study candidates’ medical records in detail for study eligibility.
• Ensure informed consent, initiate patient enrollment, and ensure accurate enrollment records are maintained.
• Educate clinical teams, ancillary departments, and patients to ensure safe and accurate protocol implementation. Coordinate and communicate regularly with study counterparts at Clinical Research Support.
• Develop and maintain tools for study implementation, which may include data collection tools, study reference materials, and study specific orders.   Revise and utilize tools as necessary to fulfill the aims of the clinical trials.
• Initiate scheduling of patient clinic visits and on-going study visits.  Attend patient visits and ensure clinical procedures, lab tests, and other protocol specific activities are completed as outlined in the protocols.
• Collaborate with Investigational Drug Services (IDS) on drug assignment, dispensation information, and maintain regular communication regarding status of study subjects.
• Ensure study drug self-administration and accountability with patients, perform non-clinical ECGs, administer study questionnaires and other protocol-driven non-clinical assessments.
• Function as a protocol liaison with clinical teams, patients, and when necessary, other institutions or drug companies. 
• Maintain appropriate source documentation and complete or assist with accurate data entry into case report forms in a timely manner. 
• Coordinate monitoring visits and respond to queries and other requests from study monitors in a timely manner.
• Understand clinical trial budget and billing plans for patients enrolled on clinical trials. As needed, p.
• Provide input regarding IRB correspondence and regulatory documentation. 
• As needed, identify and report adverse events in accordance with protocol, regulatory guidelines, and institutional policy.
• As needed, complete requisition forms, assemble kits for upcoming research visits, transport laboratory samples, and ensure samples are processed and shipped according to study specific guidelines, while tracking and maintaining research supplies.
• Maintain thorough knowledge in the field through attending related project meetings and symposia, reading related literature, and maintaining professional associations.
• Provide back up for other Clinical Research Coordinators as needed. Provide back up for Data Coordinator on applicable trials.
• Other duties as assigned.

Qualifications

• Associate's degree or higher in related field
• Minimum of 1-2 years of clinical research or related experience. 
• This position requires excellent organizational skills, attention to detail, ability to problem solve and to prioritize multiple competing tasks in a dynamic environment.
• Must be a self-starter with the ability to locate resources and operate productively in an environment where standard operating procedures, guidelines and policies are not always available.
• Collaborative focus is essential, as well as strong written and verbal communication skills, including computer skills.
• Onsite work is required for patient visits. Must have the flexibility to manage patients visits that occur before or after regular work hours.

PREFERRED QUALIFICATIONS

• Bachelor's degree in related field
• 2+ years of clinical research or related experience
• CCRP or CCRC accreditation 
• Previous experience in oncology research

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Antibody Research Group within the Clinical Research Division has an outstanding opportunity for a 60-75% FTE Clinical Research Nurse. The Clinical Research Nurse will participate in the planning, coordination, and implementation of clinical research studies involving innovative radoiummontherapy treatments for patients with hematologic malignancies. This position is currently funded for two years with the potential of becoming a regular position.

This individual will work under the supervision of the Principal Investigator (PI), and/or Lead Clinical Research Nurse, and will be required to perform his/her/their responsibilities with a high level of independence within the scope of study protocol(s) and institutional guidelines, and RN License Scope of Practice. This position will be part of a larger research team allowing for collegial support and cross coverage.

Responsibilities

NURSING DUTIES BY CATEGORY

Principal Investigator Support:

• Complete protocol specific nursing assessments for study participants with appropriate documentation in the medical record.
• Monitor lab results and outside medical records. Communicate clinically significant events to the PI and triage as necessary.
• May act as sub-investigator when the principal investigator designates protocol specific responsibilities to the research nurse that are within the research nurse scope of practice.

Collaboration:

• Identify trends in side effects and work with the principal investigator, the clinic nurse, Transplant Team and/or outside facilities to develop and evaluate patient management strategies.
• Collaborate professionally and regularly with clinic staff and research team members at UW, SCCA,sponsors and outside teams to provide seamless patient care for research participants.
• Interact with staff at outside facilities to ensure continuity of care for research participants as well as ensure protocol requirements are met. 
• Coordinate with PI, Clinic Nurses, & Pharmacists to manage side effects/adverse effects of study drugs with either concurrent medications or sponsor supplied study drugs.

Education:

• Provide protocol specific nursing education to study participants, caregivers, and colleagues.

Participation in Direct Patient Care at UWMC: 

• Fulfill requirements of UWMC and SCCA Credentialing.
• Perform clinical procedures such as blood draws from central line catheters and peripheral sites; evaluation of skin in suspected graft vs. host disease including skin biopsies; and other procedures within RN scope of practice as necessary.
• Administer medications, including study drugs, biologicals, and radioimmunoconjugates (with radiation safety training), according to protocol and within RN scope of practice.
• Assess patient and monitor for side effects to study drug with appropriate response including administration of PRN medications per protocol and, as necessary, consultation with PI or medical care team.

OTHER CLINICAL RESEARCH DUTIES BY CATEGORY

Principal Investigator Support:

• Serve as designee of the Principal Investigator (PI) to manage the daily clinical operations of assigned research studies in accordance with regulatory, GCP guidelines and institutional policy.
• Review study candidates’ medical records for study eligibility.

Enrollment

• Ensure informed consent, initiate patient enrollment, and ensure accurate enrollment records are maintained.

Education

• Educate clinical teams, ancillary departments, and patients to ensure safe and accurate protocol implementation.

Protocol Implementation

• Develop and maintain tools for study implementation, which may include data collection tools, study reference materials, and study specific orders. Revise and utilize tools as necessary to fulfill the aims of the clinical trial.
• Initiate scheduling of patient clinic visits, and on-going study visits. Ensure clinical procedures, lab test, and other protocol specific activities are completed as outlined in the protocols.
• Complete requisition forms, assemble kits for upcoming research visits, transport or arrange for transport of laboratory samples, and ensure samples are processed and shipped according to study specific guidelines, while tracking and maintaining research supplies.

Budget & Billing

• Understand clinical trial budget and billing plans for patients enrolled on clinical trials. Work with internal partners to obtain and submit budget and billing information.

Other Duties Which May Be Required

• Collaborate with Nuclear Medicine and/or Investigational Drug Services (IDS) on drug assignment and dispensation information, and maintain regular communication regarding status of study subjects.
• Function as a protocol liaison with clinical teams, patients, and when necessary, other institutions or drug companies.
• Maintain or assist in maintaining IRB correspondence and regulatory documentation. Prepare or assist in preparing consent forms, continuation review reports, protocol modifications, and other study reports.
• Maintain appropriate source documentation, and complete or assist with accurate data entry into case report forms in a timely manner.
• Coordinate monitoring visits and respond to queries and other requests from study monitors. Identify and report adverse events in accordance with protocol, regulatory guidelines, and institutional policy.
• Participate in the review of charges for patients on clinical trials to ensure billing compliance. Travel for industry sponsored investigator meetings.
• Maintain thorough knowledge in the field through attending related project meetings and symposia, reading related literature, and maintaining professional associations.

Other duties as assigned.

Qualifications

• Must have a Nursing degree and be a Licensed Registered Nurse in the State of Washington.
• Applicant must have a minimum of two years of nursing experience, with previous experience in hematology, oncology and/or research nursing preferred.
• This position requires excellent organizational skills, attention to detail, ability to problem solve and to prioritize multiple competing tasks in a dynamic environment.
• Strong candidates will have the ability to function independently and the flexibility to adapt to changes in treatment plans.
• Collaborative focus is essential, as well as strong written and verbal communication skills, including computer skills.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Data Coordinator III will abstract clinical research data from patient medical charts, code, edit and generally prepare the information according to the CIBMTR standards.

Responsibilities

• Key enter data into online Web based application, or record on specific data forms for submission to CIBMTR. Keep up to date with changing forms and procedures. Assist with data queries as requested. Perform other duties as requested by supervisor.
• May work with the Immunotherapy Department to coordinate data collection and submission into REDCap database
• May be required to travel to meetings and/or conferences
• HIPAA Training, confidentiality training, human subjects training, EPIC and Cerner knowledge, additional training as needed

Qualifications

• BA/BS/RRA/ART, or two year degree in the medical field
• 3+ years of experience in medical records, cancer registry, or related field
• Previous CIBMTR experience preferred
• Must be able to meet required reporting deadlines
• Knowledge of medical records and strong medical terminology a must

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Responsibilities

The Silberstein lab is recruiting a Lab Aide to perform routine laboratory tasks in order to help support a lab under the supervision of the Principal Investigator. A commitment of at least one year is expected.

Primary responsibility will be murine colony maintenance/PCR genotyping. Other responsibilities will include re-stocking lab supplies, processing biohazard waste, making reagents. 

Qualifications

• A high school diploma or GED and current enrollment in college at the sophomore or higher level, with prior introductory biology and chemistry preferred but not required
• To be successful in this position, the lab aide must be detailed oriented, organized, capable of maintaining thorough records, and be able to work efficiently under supervision
• Attendance of lab meetings and involvement in a research project will be encouraged

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

The Fred Hutchinson Cancer Research Center (Fred Hutch) and the University of Washington (UW) Department of Pediatrics, Division of Hematology Oncology are jointly recruiting a full-time faculty member at the Research Associate/Acting Instructor level. This is a full-time, 12-month service period, annual appointment. The primary appointment will be in the Clinical Research Division of Fred Hutch.

The Fred Hutch, home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation and immunotherapy, Fred Hutch and the UW provide a unique environment for conducting translational research and clinical care. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is a National Cancer Institute-designated comprehensive cancer center.

The selected individual for the advertised position is expected to participate in a year-long fellowship program with the goal of becoming an expert in bone marrow transplantation and Immunotherapy. This position will rotate through outpatient Hematopoietic Cell Transplantation (HCT) services (autologous and allogeneic transplant, immunotherapy, Long Term Follow Up) and on the inpatient transplant service initially as a primary care provider with increasing levels of independent patient care responsibility over the course of the year.  Exposure to some of our unique clinical programs, including non-malignant transplantation, high risk leukemia, and survivorship, will be part of the learning experience as well.  Approximately 75% of the year will be devoted to clinical activities with the remaining time available for the opportunity to participate in clinically focused research projects, which will be determined based on identification of mentors and projects. University of Washington faculty engage in teaching, research and service.

Anticipated start date would be July 1, 2021.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here. 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   
 
A Post-Doctoral Research Fellow position is available immediately under the guidance of Dr. Matthias Stephan, M.D., Ph.D., (visit the lab web page by clicking here) to explore the fast-developing and highly interdisciplinary field of immunobioengineering. Using next-generation immunomodulatory synthetic materials, the Post-Doctoral Fellow will develop new approaches - beyond existing T-cell-based therapies - to therapeutically manipulate the immune system against cancer. (https://www.nature.com/magazine-assets/d41586-017-08701-8/d41586-017-08701-8.pdf) The successful applicants will fabricate stimulatory biomaterial devices, drug delivery systems and bioactive substances and test their therapeutic potential in preclinical tumor models of adoptive T-cell therapy. The successful candidate will be a scientifically driven, well organized self-starter.

Responsibilities

• Designing mRNA nanoparticles for the in situ programming of disease-specific immune cells 
• Designing implantable biomaterials to locally deliver and functionally support tumor-reactive T cells. 
• The position will involve the fabrication of nanoparticles, repeated administration into murine, immune phenotyping, bioluminescent tumor imaging, but cell culture, cell sorting, flow cytometry, intercellular staining, transfections, ELISPOT and Chromium Release Assays 

Qualifications

• Suitable applicants should have a recent PhD in immunology or a related field. 
• The ideal candidate will work well in an interactive scientific environment, be intellectually curious, and have experience in all aspects of cellular immunology. 
• Critical skills include extensive animal science knowledge and extensive experience with animal handling, direct, hands-on experience with, and extensive knowledge of, cellular immunology, oncology, cell-based immune functional assays, flow cytometric analysis and isolation of transformed and primary cells, modulation of tumor microenvironments, and relevant statistical analysis. 
   

Please include a cover letter describing your interest in this opportunity and suitability for the role with your application.  

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here. 

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   
  
Two Post-Doctoral Research Fellow positions are immediately available with Dr. Anthony Rongvaux, Ph.D. at Fred Hutchinson Cancer Research Center. The Rongvaux Lab uses state of the art humanized murine models to studies innate immune responses specific to the human species. This research has applications in both cancer and infectious disease modalities, and ranges from fundamental research to the development of novel drugs and immunotherapies. 

Responsibilities

Innate immunity and cancer 
Most cancer deaths happen because the cancer has spread to distant sites throughout a patient’s body—a phenomenon called metastasis. Why does metastasis occur, and how can we stop it to save lives? 
  
It has been known for over three decades that a high density of macrophages in the tumor microenvironment correlates with metastatic progression and poor patient survival. However, the mechanisms by which macrophages support cancer remain incompletely understood. Our lab has developed unique humanized murine models for immuno-oncology studies. With these models, we have identified physiologically relevant macrophage populations involved in tumor support. We are currently studying the fundamental biology of these macrophages, and developing new therapeutic agents to target them. 
  
Innate immunity to HIV infection 
Over 35 million people are living with HIV worldwide. About 40% of them don’t have access to antiretroviral therapies, resulting in over half a million deaths annually. 
  
Acute HIV infection induces a rapid inflammatory response, characterized by the production of large amounts of cytokines. However, this immune response is ineffective at controlling the virus. As a consequence, the virus can establish chronic infection and, if not treated, progress to a lethal disease. Understanding why the natural immune response to HIV infection does not confer protection, could help us design more effective vaccine strategies. 
  
Using state of the art humanized murine models, single-cell RNA sequencing and genome editing, the postdoctoral fellows will study the mechanisms by which the immune system detects, and responds to transformed or infected cells. Understanding how the immune response fails to restore homeostasis is a prerequisite to design novel therapeutic or vaccine strategies. 

Qualifications

• Applicants will have a recent PhD in Immunology, Immuno-oncology, Cellular & Molecular Biology or a closely related field 
• The ideal candidate will have a research background in immunology with robust skills in molecular and cellular biology, and animal studies. Desirable skills include bioinformatics analysis, scientific writing and presentations 
• Strong interest in immunological applications in cancer and/or HIV infection. 
• To be successful in this position, the post-doctoral research fellow must be highly motivated with a track record of productive research, exemplified by at least one first author publication(s) and presentations, and willing to work in a highly collaborative, fast paced, collaborative and dynamic environment. These positions are suited to someone who enjoys mastering new skills, multitasking and working in a multiple team environment 

Overview

Cures Start Here. Fred Hutchinson Cancer Research Center (Fred Hutch), home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, Fred Hutch’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Responsibilities

A highly qualified and motivated post-doctoral research fellow is sought to join the laboratory of Dr. Sunil Hingorani (https://research.fhcrc.org/hingorani/en.html) at Fred Hutchinson Cancer Research Center in Seattle, WA.

Our laboratory investigates molecular and cellular mechanisms of pancreatic ductal adenocarcinoma (PDA) pathogenesis.  The murine models of distinct genetic subtypes of pancreas cancer that we have developed form the basis of our integrated, systematic, and multidisciplinary research program.  Our efforts are directed at identifying and overcoming stromal barriers to treatment (including elevated interstitial pressures, activated fibroblasts, and multiple mechanisms of immune suppression); identifying and disrupting molecular drivers of metastasis; and developing immune-based strategies.  Our ultimate aim is to reduce our discoveries to practice in the clinic in order to radically transform the approach and prognosis for patients with this devastating disease.

Qualifications

Successful applicants will have:

• A Ph.D. in the field of molecular biology, biomedical engineering, biochemistry, biophysics, cancer biology, immunology or genetics
• Experience with standard molecular and cellular biology techniques
• A demonstrated track record of productive research
• Experience with generation and characterization of genetically engineered murine models, advanced imaging techniques, and/or gene targeting is highly desired
• Ability to develop create approaches to experimental design
• Ability to work both independently and as part of a laboratory team  

Overview

Cures Start Here. Fred Hutchinson Cancer Research Center (Fred Hutch), home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, Fred Hutch’s five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children’s, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Walter Laboratory in the Clinical Research Division is recruiting an outstanding postdoctoral research fellow to work as part of a team investigating new treatments for patients with acute myeloid leukemia (AML) primarily focused on improving existing, and developing novel, antibody-based immunotherapies, and rendering them safer for clinical application. Current projects include preclinical drug development/testing (in part with academic and industry partners), studies on mechanisms of action and resistance of antibody-based therapeutics and identification of strategies to overcome these limitations, and development of approaches to protect normal tissues from the toxicities of AML-targeted therapies (e.g. via use of genome editing). We anticipate this position will commence July/August 2020.

Responsibilities

The newly hired fellow will work under the direction of the Principal Investigator and senior laboratory personnel and will be involved in the following techniques/duties:

• Generation of recombinant antibodies and other protein therapeutics via transient and permanent expression systems
• Conduct of immunization strategies to raise new antibodies
• Generation of engineered/gene-edited human leukemia cells
• Tissue culture of mammalian cell lines and patient-derived primary human cells
• Antibody drug conjugate (ADC) cytotoxicity, antibody-dependent cellular cytotoxicity, T-cell and NK-cell cytotoxicity assays
• Flow cytometry-based immunophenotyping, FACS isolation of mammalian cells
• Purification, cloning, and manipulation of RNA, cDNA and genomic DNA
• PCR and RT-PCR, including quantitative assays using qPCR
• Lentiviral vector modification, lentiviral particle preps and viral transduction
• Protein gels, immunoprecipitation, western blotting, immunofluorescence microscopy
• General laboratory duties and maintenance of laboratory equipment

Qualifications

Required qualifications:

• A recent PhD in a relevant field of biology such as immunology, cell and molecular biology, genetics, biochemistry, pathology, bioinformatics, or genome sciences
• Ability to drive an individual project but also be highly collaborative with academic and industrial partners
• Ability to work independently and with scientific rigor
• Interest in academic career and applying for independent funding support
   

To be successful in this position, the postdoctoral research fellow must be organized, clear and concise in their communication, enthusiastic, a team player, and have a desire to establish a career as a future independent investigator. Fellowship opportunities are available through several philanthropic and government organizations; fellow will have administrative support for the application process.

Applicants must include:

• Cover letter discussing your interest in this position, research interests and career goals
• Curriculum Vitae
• Contact information for three references

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Responsibilities

A lab in the Stem Cell and Gene Therapy program has a position for a postdoctoral fellow / research associate to study novel immunotherapy approaches to target T cells in vivo. The position involves additional responsibilities, such as development of immune-based conditioning regimens, processing and analysis of primary blood and tissue samples, and culture/analysis of tumor samples and other tissues. The candidate will study and develop methods to maximize T cell transduction and in vivo delivery of viral vectors. They will be expected to work closely with diverse study personnel and publish and present their work in both internal and external events.

Qualifications

Required:

• A PhD or MD in a scientific field is required
• The individual must possess knowledge of T cell biology, basic immunology, vector construction and multicolor flow cytometry

Preferred:

• Two years of post-doctoral research experience
• Background in transplantation biology or immunology is highly desired
• Experience is preferred in one or more of the following areas: hematopoietic T cell cultures/model systems, in vivo studies, and/or basic bioinformatic analysis techniques
• Previous experience in gene therapy/gene editing, and/or molecular biology techniques e.g. quantitative PCR and cloning is desired, but not required
• To be successful in this position, the candidate must be highly motivated and able to work independently to design and execute experiments, possess a high level of initiative and attention to detail, and must also be able to multi-task and prioritize work at short notice. They must also be capable of working independently in a team environment.
• Candidates with excellent organizational skills and communication skills (written and oral) are encouraged to apply.

A statement of research interests and/or a cover letter are required. Salary will be commensurate with (appropriate) experience.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Silberstein lab is seeking to recruit a post-doctoral fellow who is interested in pursuing laboratory-based research project.

The main goal of the laboratory is to leverage the knowledge of hematopoietic stem cell biology and bone marrow microenvironment in order to develop new therapeutic approaches to promote normal HSC function in bone marrow failure and to prevent development of myeloid malignancies. For the details of our prior work, please see Silberstein et al, Cell Stem Cell 2016, Goncalves, Silberstein et al, Cell 2016).

Responsibilities

• The lab is part of a Stem Cell and Gene Therapy Program at the Fred Hutch and interacts closely with other laboratories within the Program (Kiem, Adair, Bernstein, Hadland, Doulatov, Lee) and those within Integrated Immunotherapy Research Center (Dudakov, Headley).
• There will be ample opportunities for data presentation and informal discussions.
• They will be encouraged to develop research ideas and branch out into more independent projects.
• Mentorship and support for post-doctoral fellowship applications will be provided. 

Qualifications

• The candidate is expected to have a PhD and/or MD and a strong interest in stem cell research and commitment to basic/translational science in hematopoiesis.
• Background in cancer biology is not required but would be a bonus
• Willingness to work with murine models is essential
• Applications from trainee hematologists who are considering a laboratory-based research project are welcome
• Excellent verbal and written communication skills are required

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Reporting to the Senior Operations Director, the Research Administrator, an essential part of the Stem Cell and Gene Therapy Program and of the Clinical Research Division (CRD) Administrative team, will work under the direction of the Program Head. Investigators within the Stem Cell & Gene Therapy Program conduct research using large and small vertebrate animals and infectious agents, as well as clinical trials requiring GMP, FDA and IND compliance. Responsibilities of the Research Administrator will include management and oversight for program finance and administration, grants and contracts, and regulatory compliance, as well as compliance with Center policies and procedures. The Administrator also plays an important role in staff recruitment, training and performance management.

Responsibilities

• Manage grants, contracts and research agreements awarded by a variety of funders including Federal agencies, private foundations and commercial enterprises
• Ensure compliance with sponsor-specific reporting requirements, including tracking deadlines for progress reports, quarterly/annual financial reports and project closeouts
• Establish and monitor budgets and spending, ensuring compliance with regulations/guidelines
• Proactively communicating about issues or concerns that may impact successful completion of the research
• Preparing regular, relevant and timely reports for PIs and the CRD regarding spending, staffing, and future projections
• Monitoring program employees’ effort and salary allocation; assisting PIs with monthly effort reporting
• Coordinating the preparation of new and renewal grant applications, reviewing application guidelines, communicating requirements to the PIs, and facilitating submission together with relevant departments in Fred Hutch administration
• Serving as a liaison with administrative departments within Fred Hutch and at collaborating institutions, including the University of Washington
• Partnering with the University of Washington and other organizations on collaborative proposals, reporting, and budget management
• Assisting Human Resources by providing documents for annual merit & performance evaluations, employee on- and off-boarding and international work visas when required
• Preparing administrative documents and ensuring regulations are followed for Human Subjects, Vertebrate Animals, and Hazardous Materials research
• Assisting laboratory personnel as needed with purchasing, shared resources access, and training requirements
• Other administrative tasks needed to ensure an efficient and orderly research operation

Qualifications

Required:

• BA in Accounting, Finance, Public Administration, or related field. Relevant experience can substitute for educational requirement.
  • Research Administrator III minimum requirements- Three years in pre-award and post-award grant and contract management
  • Research Administrator IV minimum requirements- Five years in pre-award and post-award grant and contract management
• Knowledge of relevant regulatory requirements affecting sponsored research, and ability to apply this knowledge
• Effective and professional oral and written communication skills, with the ability to tailor communications to specific audiences
• Ability to navigate complex internal systems and departments while exercising sound judgement and discretion
• Proficient with complex budget development and use of reporting tools
• Proficient in fiscal and budgetary management
• Advanced skills in Word, Adobe Acrobat Pro, and Outlook
• Advanced skills in Excel including familiarity with pivot tables
• Excellent time management and prioritization skills, with the ability to effectively manage multiple and competing demands
• Demonstrated ability to function independently while exercising skill and informed professional judgment
• Highly organized and detail oriented
• Demonstrated ability to work successfully as part of a diverse team
• Excellent written and oral communication skills and the ability to communicate effectively with personnel from a variety of levels

Preferred:

• Strong organizational and problem-solving skills and the ability to manage competing priorities
• The ability to work independently, soliciting direction or assistance from the Program Administrator as required
• Experience in preparing and managing grants and contracts
• Experience working in a research organization, a university/medical school setting, or other complex non-profit organization

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

A Clinical Research Division laboratory that studies hematopoietic stem cell and T cell biology and develops novel gene therapy and gene editing strategies is recruiting a postdoctoral fellow or research associate to participate in preclinical and in vivo studies.

Responsibilities

The position involves additional responsibilities, such as:

• Development of immunological assays, processing of primary tissue samples, and culture/analysis of cells infected with HIV and related viruses.
• The candidate will study and develop methods to characterize immune responses against gene and cell therapy products, and will work under the PI and other senior members of the research team.
• The candidate will be expected to work closely within a diverse team of bench scientists, graduate students, and post-graduate team leaders, and publish and present their work in both internal and external events.

Qualifications

• A PhD or MD in a scientific field is required. 
• The individual must possess knowledge of advanced immunology assays, including extensive multi color flow cytometry experience. 
• Previous experience in infectious and/or genetic diseases, and a background in hematopoietic stem cell and/or T cell biology are highly desired.
• Cellular immunology experience required.
• Experience is preferred in one or more of the following areas: hematopoietic stem cell cultures/model systems, chimeric antigen receptor (CAR) T cell manufacturing, in vivo studies, flow-assisted cell sorting, and/or molecular biology techniques e.g. quantitative PCR and plasmid cloning.
• Previous experience in gene therapy/gene editing, and/or basic bioinformatics is desired, but not required.
• To be successful in this position, the candidate must be highly motivated and able to work independently to design and execute experiments, possess a high level of initiative and attention to detail, and must also be able to multi-task and prioritize a diverse experimental portfolio.
• The candidate must also be capable of working independently in a team environment.
• Candidates with excellent organizational skills and communication skills (written and oral) are encouraged to apply.
• A cover letter, including a research statement is required.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Greenberg lab is looking to hire a research technician to assist with preclinical evaluation of T cell receptors that are being developed for TCR gene therapy.

Responsibilities

Include cell culture and cell line maintenance of murine and human cells, performing molecular biology techniques (generating antigen-specific T cells, transduction with retroviral or lentiviral vectors, FACS sorting and expanding cells in vitro, analyzing cell phenotype and function using techniques including flow cytometry, proliferation assays, cytokine production assays, cytotoxicity assays, PCR, RT-PCR, sequencing, ELISA.

The research technician also needs to assist with literature reviews, contribute to the preparation and presentation of written and oral progress reports, assist in the publication of results and assist with other duties needed by the manager.

Qualifications

• BA/BS in a scientific field required.
• Must have scientific knowledge in the area of study and basic laboratory skills. 
• Independent research experience in addition to school lab experience is usually necessary.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

The Silberstein lab is seeking to recruit a Research Technician I-II.

The main goal of the laboratory is to combine basic stem cell biology and clinically relevant murine models in order to develop new therapeutic approaches to promote hematopoietic stem cell function in bone marrow failure and to enhance hematopoietic reconstitution after bone marrow transplantation. We are particularly interested in using microenvironment-derived molecules as drugs or therapeutic targets, and have identified several novel niche factors using proximity-based single cell analysis as a discovery strategy (for details, please see Silberstein et al, Cell Stem Cell 2016, Goncalves, Silberstein et al, Cell 2016).

Responsibilities

A successful candidate will work as a part of the highly collaborative team and focus on conducting animal experiments which involve stem cell transplantation, fluorescently-activated cell sorting/analysis and molecular studies of stem cells/progenitors. They will also share responsibility for murine colony maintenance.

The incumbent will be part of a Stem Cell and Gene Therapy Program at the Fred Hutch and interact closely with other laboratories within the Program (Kiem, Adair, Bernstein, Hadland, Doulakov) and those within Integrated Immunotherapy Research Center (Dudakov, Turtle).

Qualifications

Required:

• This position requires a bachelor's degree in a biological science and some research experience or laboratory knowledge
  • Research Technician I minimum qualifications - BA/BS in a scientific field required. Must have scientific knowledge in the area of study and basic laboratory skills. Independent research experience in addition to school lab experience is usually necessary.
  • Research Technician II minimum qualifications - Intermediate level position requiring 2 years previous experience working in a laboratory and BA/BS. Independent research experience outside of laboratory course work is usually necessary.
• Strong interest in stem cell research/bone marrow disorders
• Excellent written and verbal communication skills
• To be successful in this position, the technician must be highly motivated, have a high level of initiative, work carefully, and keep detailed records. They must also be capable of working independently in a teamwork environment and have excellent interpersonal and communication skills.
• A short cover letter explaining why a candidate has chosen to apply to the position
   

Preferred:

• Master's degree in a relevant scientific discipline (can substitute for 2 years of professional research experience)
• Previous experience of working with murine models is not essential, but one of the chief responsibilities will involve handling the animals daily and performing standard
• Some multi-parameter flow cytometry experience (undergraduate research or post graduation)
• Candidates considering medical/graduate schools are encouraged to apply

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here. 
  
At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.    
 
The Turtle Lab Turtle Lab is looking for a Staff Scientist who will work on independent and collaborative projects developing adoptive T cell immunotherapy for hematologic malignancies within the Program in Immunology and Clinical Research Division at Fred Hutch.  

Responsibilities

The successful applicant will develop and execute in-depth characterization studies and correlative analyses to support the development of CAR-T cell therapies. Successful candidates will have a strong foundation in human T cell biology and experience with standard and next generation analytical platforms for the characterization of T cell phenotype, differentiation, and function.

Qualifications

• Applicants will have a PhD in a biological science and 2+ years of post-doctoral related experience 
• Candidate must have a strong background in immunology, ideally in CAR-T cell engineering and T cell functional assays.
• Robust skills in molecular and cellular biology including flow cytometry (multicolor panel design) ideal
• Wet lab experience in CITEseq or single cell RNA sequencing using 10X Genomics systems preferred

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

At Fred Hutch, we believe that the innovation, collaboration, and rigor that result from diversity and inclusion are critical to our mission of eliminating cancer and related diseases. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an antiracist organization.  We are committed to ensuring that all candidates hired share our commitment to diversity, antiracism, and inclusion.   

Clinical Biostatistics is seeking a statistical research associate (SRA) to support studies conducted within the Clinical Research Division (CRD) of Fred Hutch. The Clinical Biostatistics department is composed of 5 faculty members, 6 SRAs, and 9 programmers/data managers. The group conducts collaborative statistical research related to clinical research projects for members within the CRD. In collaboration with CRD principal investigators, the department is responsible for the design and analysis of Phase I, II and III clinical trials and the analysis of data from observational studies related to hematopoietic cell transplantation (HCT) and solid tumor research.  

Responsibilities

This position will work closely with several PI’s and their associated research teams on a variety of studies. Responsibilities will include:

• Study design and analysis of clinical data with a focus on, but not limited to, high-dimensional data from genomics and molecular biology.
• The successful candidate will be supervised and supported by the faculty and programming staff within Clinical Biostatistics but will be expected to be able to work independently, grasp the biologic fundamentals of the target diseases, and enjoy being a key member of a very active research consortium.

Qualifications

• MS in Statistics or Biostatistics required
• At least 2 to 3 years of relevant experience in a biomedical field
• Proficiency with the R programming language and statistical models; familiarity with other statistical software packages (e.g., SAS, Stata) preferred
• Strong programming skills required
• Demonstrated strong communication and interpersonal skills
• Experience in managing varied data types/formats and the ability to juggle multiple projects required
• Must be able to clearly convey complicated statistical concepts to non-quantitative scientists
• Strong writing skills required
• Must be able to work independently and with a diverse group of people.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through work at Fred Hutch is requested of all finalists.