Fred Hutchinson Cancer Research Center invites applications for an open faculty position in the Division of Basic Sciences. Recruitment at an Assistant Member level is preferred but we will consider more senior applicants. We seek an exceptional structural biologist conducting fundamental research within areas of molecular and cellular biology that possess significant potential for novel biological insight and discovery. A particularly strong expertise and focus on the use of Cryo-electron microscopy (CryoEM) as their primary experimental approach is required.
Fred Hutch provides outstanding colleagues, a collegial atmosphere, and a wealth of resources to support junior faculty success. Graduate students are drawn from the outstanding ‘Molecular and Cellular Biology’ and ‘Biophysics, Structure and Design’ graduate programs at the University of Washington. Fred Hutch is located in a modern campus by Lake Union in Seattle, Washington, and is close to other non-profit research institutes and the University of Washington. See our website for further information (www.fredhutch.org/basic/).
For consideration, applicants must have a doctoral degree and a substantial record of achievement pre and post-doctoral. Applicants from underrepresented populations are particularly encouraged to apply. Application deadline for consideration for a fall interview: August 31, 2019. Applications will be considered on a rolling basis after the deadline if the position is not filled. Candidates should visit http://apply.interfolio.com/64580 for application instructions.
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
Off-Campus Work Study authorization is required for this position. All students must provide a Financial Aid Award Letter or an Authorization to work off-campus to verify their eligibility if selected for this position.
This position is in a laboratory that uses in vivo and in vitro models to investigate the relationship between the immune system and the microbiota. The lab specifically focuses on the interaction between anti-commensal antibodies and its role in the protection and regulation of the naïve neonatal microbiome.
The individual in this position will be involved in projects exploring the specific mechanisms in which antibodies function in the context of the microbiome. Additionally, isolating microbes that play larger roles in models with dysregulated immune systems. They will also be responsible for general laboratory duties, such as preparation of lab stock solutions, lab maintenance, autoclaving, and/or emptying biohazard waste. Major duties include:
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
A person in this position will determine the molecular basis for cell quiescence using Saccharomyces cerevisiae as a model organism. This person will use molecular biological, molecular genetic, biochemical and genomic approaches. These experiments will require extensive experience in these approaches, and therefore Ph.D. is a prerequisite for the position.
A post-doctoral research fellow is available in a lab that studies chromatin, the complex of DNA and proteins that make up our chromosomes, and how its structure controls essential processes that take place on DNA. The responsibilities of this position will be to determine how cell quiescence is achieved using Saccharomyces cerevisiae as a model organism.
A Ph.D. in molecular biology, biochemistry or other related scientific discipline is required, as well as experience in studying DNA-dependent processes including transcription, DNA replication and DNA damage response.
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
Candidates will be encouraged to build on the lab’s ideas and develop new directions for their research projects. Fred Hutch has more than 200 postdoctoral fellows working in labs across all five research divisions. We provide postdocs with the opportunity to work on the cutting edge of biomedical research in a supportive, collaborative environment with faculty and staff who are dedicated to helping their trainees achieve their career goals.
The Rajan Lab investigates mechanisms that enable energy homeostasis, specifically how fat cells relay information to the brain.
Please apply with a letter summarizing previous work experience, future research interests, and contact information for three professional references.
A postdoctoral position for a recent enthusiastic PhD graduate is available in the Rajan Lab at Fred Hutch. The Rajan lab uses multidisciplinary approaches to study how organisms sense and communicate nutrient state. We are seeking a highly motivated postdoc candidate interested in one of the following two research areas – blood brain barrier access of adipokines or innate immune molecules that intersect with metabolism-- in the Drosophila model system, with subsequent validation in murine and/or human cell systems. The postdoc candidate will carry out independent research projects and participate in lab meetings/journal clubs, as well as contribute to the smooth running of the lab.
Required:
Preferred:
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
Candidates will be encouraged to build on the lab’s ideas and develop new directions for their research projects. Fred Hutch has more than 200 postdoctoral fellows working in labs across all five research divisions. We provide postdocs with the opportunity to work on the cutting edge of biomedical research in a supportive, collaborative environment with faculty and staff who are dedicated to helping their trainees achieve their career goals.
The Rajan Lab investigates mechanisms that enable energy homeostasis, specifically how fat cells relay information to the brain.
A postdoctoral position for a recent enthusiastic PhD graduate is available in the Rajan Lab at Fred Hutch. The Rajan lab uses multidisciplinary approaches to study how organisms sense and communicate nutrient state. We are seeking a highly motivated postdoc candidate interested in one of the following two research areas – blood brain barrier access of adipokines or innate immune molecules that intersect with metabolism-- in the Drosophila model system, with subsequent validation in murine and/or human cell systems. The postdoc candidate will carry out independent research projects and participate in lab meetings/journal clubs, as well as contribute to the smooth running of the lab.
Required:
Preferred:
Please apply with a letter summarizing previous work experience, future research interests, and contact information for three professional references.
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
A quantitative biology laboratory in the Division of Basic Sciences is seeking a highly motivated postdoctoral fellow with PhD in mathematics or physics.
Our lab uses experimental biology, quantitative measurements, and mathematics to examine microbial communities. For example, how might different microbial species interact with each other to allow the community to carry out a function that would have otherwise been impossible? How might we effectively manipulate or evolve community functions? How might we extract information from time series data? Our lab provides excellent opportunities to combine theory with biology.
We are interested in recruiting an accomplished mathematician and/or physicist to tackle biological problems from the theory side.
More information about the group may be found at honeycomb.fhcrc.org.
A Ph.D. in physics, mathematics or engineering is required.
Ideally, the candidate is familiar with out-of-equilibrium stochastic processes or time series analysis.
The successful candidate should have a strong background in physics, mathematics, and/or engineering.
To apply, please submit a CV, a cover letter stating your long-term goal, and a list of professional references.
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
A hallmark of many diseases and cancers is a dysfunctional cytoskeleton. A properly functioning cytoskeleton is needed for a wide variety of cellular events ranging from cell shape to cell signaling and migration/metastasis. The Parkhurst laboratory in the Basic Sciences Division at Fred Hutch uses multidisciplinary approaches to study these dynamic structural elements in various processes including wound repair and nuclear architecture/organization. Our goal is to understand the role of these elements in regulating normal developmental events and how this regulation goes awry in diseases/cancers, thereby providing new avenues for possible therapeutic targets or to enhance the effectiveness of existing treatment modalities.
Our current research efforts are divided among studies of: (1) Molecular and cellular mechanisms of single cell wound repair, and (2) Actin and microtubule cytoskeleton dynamics mediated by the Rho1 small GTPase and its effectors; and (3) Nuclear architecture and organization.
This is an ideal position for a recent graduate who wants to gain an intense research experience before pursuing graduate and/or medical school.
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
Our laboratory focuses on how gene regulation, chromatin structure, and nuclear organization are linked, with a special emphasis on changes that occur with differentiation. This is a part-time position where effort is negotiable depending on the candidates’ skills and needs. The person in this position will be the lead on a collaborative project to define all cis-acting regulatory sequences on a genome-wide basis. The focus of this work is the isolation of defined populations of hematopoietic cells at defined stages of development and differentiation with the goal of subjecting them to a variety of molecular analyses. Samples will be obtained from wildtype and mutant mice, at baseline, and while recovering from stress. The candidate will prepare samples for analysis by Next Generation Sequencing (NGS). This work will require managing a mouse colony as well as isolating and analyzing mouse tissues.
The research technician will work under the direct supervision by the principal investigators and be working with outside collaborators. This individual will be the sole Fred Hutch person doing bench work on this project and will need to work semi-independently and be adept at balancing responsibilities. To be successful in this laboratory the technician will need to work fairly autonomously and take the lead on trouble-shooting. Excellent communication, documentation and organization skills are essential.
Required:
Preferred:
Comfort, and being facile with flow cytometry, including optimizing antibody staining and data analysis. Having job experience with this would be a major benefit.
Comfort with basic mouse husbandry, genotyping and isolation of organs. Having job experience with this would be a major benefit.
Tissue culture experience.
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The Brent lab is seeking a Research Technician IV to support our research in the causes and consequences of non-genetic phenotypic variation.
The project specifically includes design and construction of "controllers", complex artificial systems allowing tunable variation-suppressed expression of genes in mammalian cells. The Research Technician IV will also be involved in efforts to develop Augmented Reality (AR) methods and protocols to aid the controller project, and to in work to learn how to use AR to enable other researchers to better carry out a variety of fundamental experimental manipulations.
For this position, we are hoping to find an extraordinary and dedicated individual. The lab is a multidisciplinary environment and offers a number of intellectual growth paths by which scientists willing to engage can continue to develop scientifically. This position will support research activities that include but are not limited to:
Required:
Preferred:
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