Basic Sciences Job Openings

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9 Found open positions

CryoEM/Structural Biology Faculty Position

Basic Sciences Division
Category: Faculty: Associate, Assistant, and Full Member
Seattle, WA, US
Job ID: 64580

Fred Hutchinson Cancer Research Center invites applications for an open faculty position in the Division of Basic Sciences. Recruitment at an Assistant Member level is preferred but we will consider more senior applicants. We seek an exceptional structural biologist conducting fundamental research within areas of molecular and cellular biology that possess significant potential for novel biological insight and discovery. A particularly strong expertise and focus on the use of Cryo-electron microscopy (CryoEM) as their primary experimental approach is required.

Fred Hutch provides outstanding colleagues, a collegial atmosphere, and a wealth of resources to support junior faculty success. Graduate students are drawn from the outstanding ‘Molecular and Cellular Biology’ and ‘Biophysics, Structure and Design’ graduate programs at the University of Washington. Fred Hutch is located in a modern campus by Lake Union in Seattle, Washington, and is close to other non-profit research institutes and the University of Washington. See our website for further information (www.fredhutch.org/basic/).

For consideration, applicants must have a doctoral degree and a substantial record of achievement pre and post-doctoral. Applicants from underrepresented populations are particularly encouraged to apply. Application deadline for consideration for a fall interview: August 31, 2019. Applications will be considered on a rolling basis after the deadline if the position is not filled. Candidates should visit http://apply.interfolio.com/64580 for application instructions.

Lab Aide

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 14652

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

The Malik lab in the Basic Sciences Division of Fred Hutch is looking to hire a part-time lab aide. This lab aide will assist researchers with molecular evolution research in fruit fly species.  We are looking for someone who has experience in conducting genetic crosses, microscopy and basic fruit fly husbandry.  This could be an ideal position for seniors or recent graduates who have completed intro to biology and are looking to get experience working in a lab, but we encourage anyone qualified to apply.

 

The candidate must be able to work 16-20 hours per week, and to commit to the same schedule weekly or quarterly if still in school.

Qualifications

  • Completion of a high school degree is required
  • Must have completed college level coursework in Biology. Past experience in genetics and/or fruit fly husbandry is desirable.
  • Must have careful attention to detail and a reliable schedule for fixed hours every week.

Lab Aide (Work Study)

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 14510

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

Off-Campus Work Study authorization is required for this position. All students must provide a Financial Aid Award Letter or an Authorization to work off-campus to verify their eligibility if selected for this position.

Responsibilities

This position is in a laboratory that uses in vivo and in vitro models to investigate the relationship between the immune system and the microbiota. The lab specifically focuses on the interaction between anti-commensal antibodies and its role in the protection and regulation of the naïve neonatal microbiome.

 

The individual in this position will be involved in projects exploring the specific mechanisms in which antibodies function in the context of the microbiome. Additionally, isolating microbes that play larger roles in models with dysregulated immune systems. They will also be responsible for general laboratory duties, such as preparation of lab stock solutions, lab maintenance, autoclaving, and/or emptying biohazard waste. Major duties include:

  • Handling and working with Mus musculus
  • Genotyping different strains of Mus musculus with varying dysregulated immune phenotypes
  • Conduct varying assays such as ELISA, gel electrophoresis, PCR
  • Stock lab supplies, prepare reagents, autoclave and/or empty biohazard waste
  • Follow safety/biohazard precautions and procedures

Qualifications

  • A high school diploma or GED and enrollment in a university-level science degree program (e.g. biology, immunology, chemistry, or biochemistry) are required.
  • Previous or current coursework in biology and/or chemistry and past laboratory experience are preferred
  • Experience with molecular biology techniques is highly desirable but not a requirement
  • Demonstrated accuracy, attention to detail, and ability to learn new skills quickly is essential
  • Off-Campus Work Study authorization is required for this position. All students must provide a Financial Aid Award Letter or an Authorization to work off-campus to verify their eligibility if selected for this position.

Lab Aide (Work Study), Augmented Reality

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 14569

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

The Brent Lab is part of the Basic Sciences Division at the Fred Hutchinson Cancer Research Center. Work in this Division spans a wide range of basic research projects, and the Division is an exceptionally active and interactive scientific environment that offers high quality scientific education to students immersed in its activities.

 

Ideal candidates will be available for 19 hours per week and be eligible for state or federal work study. Schedule can vary depending on class or other work schedule.

Responsibilities

The Brent lab is seeking a work study student from Bio-Engineering, Electrical Engineering, Computer Science or related field, to help develop UI/UX and content for Augmented Reality (AR) guidance in lab procedures.  The lab aide will contribute to a larger project to use AR to aid biomedical research and design.

Qualifications

Required:

  • Currently enrolled as undergraduate or graduate student in a four-year university pursuing a degree Bioengineering, Electrical Engineering, Computer Science or related fields.
  • Have current work-study eligibility.
  • Flexibility and able to work independently without supervision.

Preferred:

  • Literacy in command line Ubuntu Linux and other Linux, literate in or able to learn Windows 10, familiar with image editing, and familiar with JSON.
  • The incumbent ideally should possess the skills on how to read and write scientific protocols that can be implemented into various AR programs.
  • Clean design sense and familiarity with Unity 3D.
  • Computer skills using programs such as PYTHON or MATLAB.

Post-Doctoral Research Fellow

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 14623

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

A highly motivated postdoctoral research fellow is sought to carry out a research project in the field of Epigenetics and Molecular Biology.  Recent postdocs or graduate students at the end of their training program, who are eligible for participation in NIH-funded training grants and fellowships, are especially encouraged to apply.

Qualifications

The successful candidate must have a recent PhD in a relevant biological field with a demonstrated track record of productive research and be able to work both independently and as part of a laboratory team. The candidate must also have a strong background in essential molecular and cellular biology techniques.

Post-Doctoral Research Fellow, Cell Biology

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 12653

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

A postdoctoral position for a recent enthusiastic PhD graduate is available in the Parkhurst Lab at Fred Hutch. The Parkhurst lab uses multidisciplinary approaches to study dynamic cytoskeleton processes in the regulation of normal developmental events and when mis-regulated in diseases/cancer.  We are seeking a highly motivated postdoc candidate interested in one of the following two research areas -- Cell wound repair or Nuclear architecture/organization -- in the Drosophila model system. The postdoc candidate will carry out independent research projects and participate in lab meetings/journal clubs, as well as contribute to the smooth running of the lab.

 

Salary for this opportunity will be in line with the NIH pay scale.

Qualifications

  • Recent PhD degree
  • A strong foundation in molecular and cell biology
  • Background and familiarity with Drosophila genetics desirable
  • Candidates need to be highly motivated and well-organized individuals who think independently, but enjoy working as part of a dynamic and collaborative team
  • Excellent verbal and written communication skills

Post-Doctoral Research Fellow, Neuro-immune Control of Metabolism

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 14425

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

Candidates will be encouraged to build on the lab’s ideas and develop new directions for their research projects. Fred Hutch has more than 200 postdoctoral fellows working in labs across all five research divisions. We provide postdocs with the opportunity to work on the cutting edge of biomedical research in a supportive, collaborative environment with faculty and staff who are dedicated to helping their trainees achieve their career goals.

 

The Rajan Lab investigates mechanisms that enable energy homeostasis, specifically how fat cells relay information to the brain.

Responsibilities

A postdoctoral position for a recent enthusiastic PhD graduate is available in the Rajan Lab at Fred Hutch. The Rajan lab uses multidisciplinary approaches to study how organisms sense and communicate nutrient state.  We are seeking a highly motivated postdoc candidate interested in one of the following two research areas – blood brain barrier access of adipokines or innate immune molecules that intersect with metabolism-- in the Drosophila model system, with subsequent validation in murine and/or human cell systems. The postdoc candidate will carry out independent research projects and participate in lab meetings/journal clubs, as well as contribute to the smooth running of the lab.

Qualifications

Required:

  • A recent PhD degree in biology or related field.
  • A strong foundation in molecular and cell biology.
  • Candidates need to be highly motivated and well-organized individuals who think independently, but enjoy working as part of a dynamic and collaborative team.
  • Excellent verbal and written communication skills.

Preferred:

  • Background and familiarity with Drosophila genetics and/or mammalian cell culture desirable

Please apply with a letter summarizing previous work experience, future research interests, and contact information for three professional references.

Research Technician II, Cell Biology

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 14147

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


A hallmark of many diseases and cancers is a dysfunctional cytoskeleton. A properly functioning cytoskeleton is needed for a wide variety of cellular events ranging from cell shape to cell signaling and migration/metastasis. The Parkhurst laboratory in the Basic Sciences Division at Fred Hutch uses multidisciplinary approaches to study these dynamic structural elements in various processes including wound repair and nuclear architecture/organization. Our goal is to understand the role of these elements in regulating normal developmental events and how this regulation goes awry in diseases/cancers, thereby providing new avenues for possible therapeutic targets or to enhance the effectiveness of existing treatment modalities.


Our current research efforts are divided among studies of: (1) Molecular and cellular mechanisms of single cell wound repair, and (2) Actin and microtubule cytoskeleton dynamics mediated by the Rho1 small GTPase and its effectors; and (3) Nuclear architecture and organization.

Responsibilities

  • The research technician will primarily carry out an independent research project that involves cell biology, developmental genetics, and molecular biology.
  • The technician will participate in lab meetings and journal clubs.
  • Other responsibilities include general lab maintenance (ordering, caring for Drosophila flies, fly media preparation), and other duties as needed.

This is an ideal position for a recent graduate who wants to gain an intense research experience before pursuing graduate and/or medical school.

Qualifications

  • A bachelor’s degree in a biological science and bench research experience are required.
  • Reliability is essential.
  • Good verbal and written communication skills.
  • Good interpersonal skills.
  • To be successful in this position, the technician must have scientific curiosity, a high level of self-motivation, the ability to take instruction and correction and to follow directions, good organizational skills, the ability to work and think independently, and wants to stay at least two years.
  • Must be able to distinguish different intensities and hues of red color.

Staff Scientist, Molecular Mechanisms Underlying Fat-Brain Relay

FH Basic Sciences Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 14480

Overview

Fred Hutchinson Cancer Research Center, home to three Nobel laureates, is an independent, nonprofit research institute based in Seattle. Its interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases.

 

Staff Scientist opportunity in neuro-immune control of metabolism

 

The Rajan lab is located in the Basic Sciences Division at Fred Hutch in Seattle. Grounded in a steadfast commitment to scientific excellence and bold creativity, the Basic Sciences Division encourages robust, ongoing collaboration among divisions, laboratories and clinical researchers. Research from this Division has yielded several landmark breakthroughs and scientific advances, including two Nobel Prize-winning discoveries that may inform new approaches to treatment. Notably, this Division values contributions from scientists who have completed their post-doctoral studies and join labs as staff scientists to continue contributing to discoveries, while working along side the principal investigators to move science in new directions and mentor junior colleagues.

Responsibilities

A Staff Scientist position is available in the Rajan Lab at Fred Hutch. The Rajan Lab uses multidisciplinary approaches to study how organisms’ sense and communicate nutrient state. We are seeking a highly motivated candidate interested in one of the following two research areas – blood brain barrier access of adipokines or innate immune molecules that intersect with metabolism-- in the Drosophila model system, with subsequent validation in murine and/or human cell systems. The candidate will carry out independent research projects, help to write grants and papers, and engage and guide technicians. They will participate in lab meetings/journal clubs, attend conferences as well as contribute to the smooth running of the lab.

Qualifications

Please apply with a letter summarizing previous work experience, why a long-term staff scientist role is being considered at this career stage. Also provide contact information for three professional references.


Required:

  • PhD degree in Biology or related fields and three years of postdoctoral research experience
  • A strong foundation in molecular and cell biology
  • Candidates need to be highly motivated and well-organized individuals who think independently, enjoy working as part of a dynamic and collaborative team and are enthusiastic about mentoring junior scientists
  • Excellent verbal and written communication skills


Preferred: 

  • Candidates with a very strong background in one of the following will be given preference: Drosophila genetics; cell-free systems and biochemical reconstitution; and/or mammalian cell culture.
  • Five years or more of postdoctoral research experience.
  • Expertise in glial cell biology, autophagic processes or innate immunity.

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