Basic Sciences Job Openings

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5 Found open positions

Post-Doctoral Research Fellow

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 14145

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer with minimal side effects. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first and largest cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

A highly motivated postdoctoral research fellow is sought to carry out a research project in the field of Epigenetics and Molecular Biology. Recent postdocs or graduate students at the end of their training program, who are eligible for participation in NIH-funded training grants and fellowships, are especially encouraged to apply.

Qualifications

The successful candidate must have a PhD in a relevant biological field with a demonstrated track record of productive research, be able to work both independently and as part of a laboratory team. The candidate must also have a strong background in essential molecular and cellular biology techniques as well as research experience in chromatin and epigenetics.

Post-Doctoral Research Fellow, Cell and Developmental Biology

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 13408

Overview

Cures Start Here. Fred Hutchinson Cancer Research Center, home to three Nobel laureates, is an independent, nonprofit research institute based in Seattle. Its interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Laboratories in the Basic Sciences Division investigate diverse areas of molecular, computational, cellular, developmental, evolutionary and structural biology, metabolism, virology and immunity. We utilize a broad range of experimental and computational approaches and model systems. Fred Hutch provides outstanding colleagues, a collegial atmosphere, and a wealth of resources, including core resources for imaging, proteomics, genomics, flow cytometry, high content screening, and small animal research. Frequent meetings and external seminars provide many opportunities for inter-lab collaborations. Careers Start Here.

Responsibilities

The Cooper lab in the Basic Sciences Division at the Fred Hutchinson Cancer Research Center is seeking new postdoctoral fellows. The Cooper lab has a demonstrated history of high impact studies of signal transduction mechanisms associated with mammalian cell migration in cell culture and in vivo model systems.


Potential projects include: investigating the interplay between tyrosine phosphorylation and ubiquitylation in cell migration; the in vivo roles of Cullin 5 ubiquitin ligase complexes; the non-adhesive functions of cadherins in cancer and development; and the dynamics of focal adhesion proteins. We are particularly interested in using live imaging of engineered cells to understand the sequence of events in cellular adhesions. Specifically, we want to know how focal adhesion turnover is regulated differently at the leading edge from under the cell body. What are the signals and how are they relayed to the adhesions? Candidates will be encouraged to build on these ideas and develop new directions for their research projects

Qualifications

Successful applicants will hold a PhD or MD and have extensive experience and interest in cell and/or developmental biology. In addition, applicants should have a 2+ years of experience working on projects in mammalian molecular, cellular or developmental biology. Hands on experience with cell imaging or murine developmental biology is desirable. The candidate should be enthusiastic, scientifically rigorous and inquisitive. Since the Cooper lab is small, the candidate will need the technical skills, confidence and drive it takes to start new directions. The candidate will be responsible for all aspects of their research project. They must be able to function independently and also be highly collaborative. Excellent written and verbal communication skills are essential.

 

To apply please submit your CV, a cover letter detailing your research interests and suitability for this position, and the names of at least two references.

Post-Doctoral Research Fellow, Mechanisms of Eukaryotic Transcription

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 13632

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

The Hahn laboratory in the Division of Basic Sciences has an immediate opening for a Postdoctoral Associate to investigate mechanisms of transcriptional regulation using yeast as a model system. Potential research projects include studies on the mechanisms of transcription activators and the genome-wide roles of transcription coactivators and regulatory factors. A variety of approaches such as genomics, molecular genetics, biochemistry and computational biology will be utilized. The precise topic of the research project will be determined jointly with the candidate and candidates that display initiative and independence will be given priority.

Qualifications

PhD in either molecular and cellular biology, biochemistry, biophysics, or related fields with ideally 0-2 years of postdoctoral experience. Preferred candidates will have experience in molecular biology and biochemistry, next generation sequencing data analysis and experimentation (e.g., ChIP-seq, RNA-seq, etc.), and experience with Python and/or R.  Published evidence of productivity and creativity and strong analytical and interpersonal skills are required. The successful candidate will have the ability to work both independently and in a highly collaborative environment. 

 

To apply, please submit a CV and a cover letter that describes your research accomplishments as well as your interest in the Hahn laboratory research program. 

Post-Doctoral Research Fellow, Molecular Neuroscience

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 12832

Overview

Fred Hutchinson Cancer Research Center, home to three Nobel laureates, is an independent, nonprofit research institute based in Seattle. Its interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Laboratories in the Basic Sciences Division investigate diverse areas of molecular, computational, cellular, developmental, evolutionary and structural biology, metabolism, virology and immunity. We utilize a broad range of experimental and computational approaches and model systems. Fred Hutch provides outstanding colleagues, a collegial atmosphere, and a wealth of resources, including core resources for imaging, proteomics, genomics, flow cytometry, high content screening, and small animal research. Frequent meetings and external seminars provide many opportunities for inter-lab collaborations.  

 

A highly motivated Post-Doctoral Fellow is sought to carry out research in the laboratory of Dr. Linda Buck at Fred Hutchinson Cancer Research Center in Seattle, WA.

 

The Buck Lab studies the molecular mechanisms and neural circuits that underlie the sense of smell and instinctive odor responses. It is interested in how the olfactory system detects myriad environmental chemicals and how the brain translates those chemicals into diverse odor perceptions, hormonal alterations, and instinctive behaviors.  It is also interested in neural mechanisms that underlie stress.  Illumination of the neural circuits underpinning these and related effects may provide clues to those affected in certain human disorders, particularly those involving stress, fear, and appetite.  The lab is particularly interested in using cutting edge technologies, such as single cell genomics, for dissecting the composition of complex neural networks.

Responsibilities

The fellow will be responsible for developing and executing a project related to current and future interests of the lab, as determined by discussions with Dr. Buck. The successful candidate will be an individual who is enthusiastic about science and is capable of independent research.

Qualifications

Required

  • PhD in molecular and cell biology or molecular neuroscience
  • Excellent knowledge of fundamental molecular and cell biology
  • Experience using molecular techniques for cloning and for analysis of nucleic acids and proteins
  • Experience using immunohistochemistry and/or in situ hybridization for analyses of gene expression


Preferred

  • Experience with RNA sequencing and bioinformatics
    • Experience in murine breeding and genotyping
  • Knowledge of neuroscience

To apply, please submit your CV, a cover letter describing your research experience and interests and contact information for three references. 

Staff Scientist, Molecular and Behavioral Neuroscience

FH Basic Sciences Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 12023

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
 
A highly motivated and experienced Staff Scientist is sought to carry out research in the laboratory of Dr. Linda Buck at Fred Hutchinson Cancer Research Center in Seattle, WA.

The Buck Lab studies the molecular mechanisms and neural circuits that underlie the sense of smell and instinctive odor responses. It is interested in how the olfactory system detects myriad environmental chemicals and how the brain translates those chemicals into diverse odor perceptions, hormonal alterations, and instinctive behaviors. Illumination of the neural circuits underpinning these and related effects may provide clues to those affected in certain human disorders, particularly those involving stress, fear, and appetite.

Responsibilities

  • Conduct research independently as well as contributing to research being done by other team members as needed
  • Research will focus on one or more research interests of the lab
  • Breed and genotype transgenic murine for specific projects
  • Prepare and analyze tissue sections for mRNA and protein expression using standard techniques utilized in the lab
  • Clone and analyze DNA for use as probes
  • Conduct experiments to analyze murine behavior
  • Prepare graphs and images of research results for presentation and publication
  • Present results obtained in group meetings

Qualifications

Minimum

  • PhD in molecular and cell biology or molecular neuroscience
  • At least five years of post-doctoral research experience
  • Excellent knowledge of fundamental molecular and cell biology
  • Experience using molecular techniques for cloning and for analysis of nucleic acids and proteins
  • Experience in murine breeding and genotyping
  • Experience in preparing tissue sections and analyzing them using immunohistochemistry and in situ hybridization


Preferred

  • Knowledge of neuroscience
  • Experience analyzing murine behavior
  • Experience with RNA sequencing and bioinformatics is a plus  

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