Basic Sciences Job Openings

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10 Found open positions

Lab Aide

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 14277

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

The Parkhurst laboratory in the Basic Sciences Division is recruiting an hourly Lab Aide for 16-18 hours per week. The lab aide will coordinate with lab members and work a consistent weekly schedule (i.e., 2x 8hrs or 3x 6 hours) with some flexibility for shift days/times. Responsibilities include:

  • Care and maintenance of fly stocks
  • General lab maintenance, including preparation of lab reagents and stock solutions, cleaning, sterilizing labware, and other duties, as assigned.

Qualifications

  • Graduation from High School or equivalent with interest in the sciences
  • Must be reliable, able to produce consistent high quality results, and able to lift trays weighing 20-30 pounds
  • Attention to detail is essential to this position
  • Some lab experience and/or college level chemistry courses preferred

Lab Aide (Work Study)

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 14182

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

 

Please note this position is a work study position. Candidate must have work study funds granted by a college or university, and must provide a work study authorization form prior to start date. Work-study eligible students from the University of Washington, Seattle University and Seattle Pacific University are encouraged to apply.

Responsibilities

A lab in the Basic Sciences Division has an opening for a part-time lab aide. This is a work-study eligible position.

 

This lab aide will clean common bench areas, ensure inventory is well-stocked, put away glassware, and assist researchers with media prep work and experiments.

Qualifications

  • Completion of a high school degree is required
  • Must be enrolled in or have completed college level coursework in Biology or Chemistry
  • Attention to detail and reliability is required.

Post-Doctoral Research Fellow, Cell Biology

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 12653

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

A postdoctoral position for a recent enthusiastic PhD graduate is available in the Parkhurst Lab at Fred Hutch. The Parkhurst lab uses multidisciplinary approaches to study dynamic cytoskeleton processes in the regulation of normal developmental events and when mis-regulated in diseases/cancer.  We are seeking a highly motivated postdoc candidate interested in one of the following two research areas -- Cell wound repair or Nuclear architecture/organization -- in the Drosophila model system. The postdoc candidate will carry out independent research projects and participate in lab meetings/journal clubs, as well as contribute to the smooth running of the lab.

 

Salary for this opportunity will be in line with the NIH pay scale.

Qualifications

  • Recent PhD degree
  • A strong foundation in molecular and cell biology
  • Background and familiarity with Drosophila genetics desirable
  • Candidates need to be highly motivated and well-organized individuals who think independently, but enjoy working as part of a dynamic and collaborative team
  • Excellent verbal and written communication skills

Post-Doctoral Research Fellow, Cell and Developmental Biology

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 13408

Overview

Cures Start Here. Fred Hutchinson Cancer Research Center, home to three Nobel laureates, is an independent, nonprofit research institute based in Seattle. Its interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Laboratories in the Basic Sciences Division investigate diverse areas of molecular, computational, cellular, developmental, evolutionary and structural biology, metabolism, virology and immunity. We utilize a broad range of experimental and computational approaches and model systems. Fred Hutch provides outstanding colleagues, a collegial atmosphere, and a wealth of resources, including core resources for imaging, proteomics, genomics, flow cytometry, high content screening, and small animal research. Frequent meetings and external seminars provide many opportunities for inter-lab collaborations. Careers Start Here.

Responsibilities

The Cooper lab is seeking a cell biologist with interests in live-cell imaging to study adhesion dynamics during cell movement.

 

Tyrosine phosphorylation-dependent protein ubiquitination regulates cell-matrix adhesion dynamics and movement of epithelial sheets. We know that tyrosine phosphorylation of specific adhesion proteins destabilizes adhesions. We found that phosphorylation also ubiquitin ligases to adhesions and that inhibiting ligase recruitment stimulates adhesion disassembly. This suggests a cycle of protein binding, phosphorylation, ubiquitination and destruction that regulates adhesion growth. In principle, this mechanism regulates the balance between adhesion assembly and disassembly, and potentially could ensure that adhesions grow at the leading edge and shrink behind. Nevertheless, the sequence of events in individual adhesions has not been determined. The in vivo significance of these regulatory events is also unknown.

 

Our present efforts are directed to:

  • Measure the dynamics of protein appearance in and disappearance from focal adhesions and build a quantitative model for adhesion assembly and disassembly.
  • Use optogenetics to artificially recruit, exclude or activate specific regulatory proteins and establish the molecular mechanism.
  • Extend the in vitro observations to in vivo development or disease systems.

Candidates will be encouraged to build on these ideas and develop new directions for their research projects.

Qualifications

Successful applicants will hold a PhD or MD and have extensive experience and interest in cell and/or developmental biology. In addition, applicants should have a 2+ years of experience working on projects in mammalian molecular, cellular or developmental biology. Hands on experience with cell imaging or murine developmental biology is desirable. The candidate should be enthusiastic, scientifically rigorous and inquisitive. Since the Cooper lab is small, the candidate will need the technical skills, confidence and drive it takes to start new directions. The candidate will be responsible for all aspects of their research project. They must be able to function independently and also be highly collaborative. Excellent written and verbal communication skills are essential.

 

To apply please submit your CV, a cover letter detailing your research interests and suitability for this position, and the names of at least two references.

Post-Doctoral Research Fellow, Mechanisms of Eukaryotic Transcription

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 13632

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

The Hahn laboratory in the Division of Basic Sciences has an immediate opening for a Postdoctoral Associate to investigate mechanisms of transcriptional regulation using yeast as a model system. Potential research projects include studies on the mechanisms of transcription activators and the genome-wide roles of transcription coactivators and regulatory factors. A variety of approaches such as genomics, molecular genetics, biochemistry and computational biology will be utilized. The precise topic of the research project will be determined jointly with the candidate and candidates that display initiative and independence will be given priority.

Qualifications

PhD in either molecular and cellular biology, biochemistry, biophysics, or related fields with ideally 0-2 years of postdoctoral experience. Preferred candidates will have experience in molecular biology and biochemistry, next generation sequencing data analysis and experimentation (e.g., ChIP-seq, RNA-seq, etc.), and experience with Python and/or R.  Published evidence of productivity and creativity and strong analytical and interpersonal skills are required. The successful candidate will have the ability to work both independently and in a highly collaborative environment. 

 

To apply, please submit a CV and a cover letter that describes your research accomplishments as well as your interest in the Hahn laboratory research program. 

Post-Doctoral Research Fellow, Molecular Neuroscience

FH Basic Sciences Division
Category: Post-Doctoral Research Fellows and Associates
Seattle, WA, US
Job ID: 12832

Overview

Fred Hutchinson Cancer Research Center, home to three Nobel laureates, is an independent, nonprofit research institute based in Seattle. Its interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Laboratories in the Basic Sciences Division investigate diverse areas of molecular, computational, cellular, developmental, evolutionary and structural biology, metabolism, virology and immunity. We utilize a broad range of experimental and computational approaches and model systems. Fred Hutch provides outstanding colleagues, a collegial atmosphere, and a wealth of resources, including core resources for imaging, proteomics, genomics, flow cytometry, high content screening, and small animal research. Frequent meetings and external seminars provide many opportunities for inter-lab collaborations.  

 

A highly motivated Post-Doctoral Fellow is sought to carry out research in the laboratory of Dr. Linda Buck at Fred Hutchinson Cancer Research Center in Seattle, WA.

 

The Buck Lab studies the molecular mechanisms and neural circuits that underlie the sense of smell and instinctive odor responses. It is interested in how the olfactory system detects myriad environmental chemicals and how the brain translates those chemicals into diverse odor perceptions, hormonal alterations, and instinctive behaviors.  It is also interested in neural mechanisms that underlie stress.  Illumination of the neural circuits underpinning these and related effects may provide clues to those affected in certain human disorders, particularly those involving stress, fear, and appetite.  The lab is particularly interested in using cutting edge technologies, such as single cell genomics, for dissecting the composition of complex neural networks.

Responsibilities

The fellow will be responsible for developing and executing a project related to current and future interests of the lab, as determined by discussions with Dr. Buck. The successful candidate will be an individual who is enthusiastic about science and is capable of independent research.

Qualifications

Required

  • PhD in molecular and cell biology or molecular neuroscience
  • Excellent knowledge of fundamental molecular and cell biology
  • Experience using molecular techniques for cloning and for analysis of nucleic acids and proteins
  • Experience using immunohistochemistry and/or in situ hybridization for analyses of gene expression


Preferred

  • Experience with RNA sequencing and bioinformatics
    • Experience in murine breeding and genotyping
  • Knowledge of neuroscience

To apply, please submit your CV, a cover letter describing your research experience and interests and contact information for three references. 

Research Technician I-II, Chromatin Regulation of Pediatric Malignancies

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 14262

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.

Responsibilities

A highly motivated research technician is wanted to carry out experiments in a collaborative project between a pediatric oncologist in our Clinical Research Division and a chromatin biologist in our Basic Sciences Division, in the field of cancer epigenetics. Research is centered on high-risk pediatric malignancies and understanding chromatin regulation driving them. This position may be particularly appealing to applicants interested in a career in medicine or working in a mix of basic and translational sciences.

Qualifications

The successful candidate will have a bachelor's degree in biology or related fields and at least 1-2 years of experience as a research technician and relevant skills in molecular and cellular biology. Contribution to a publication is preferred but not essential. The candidate should be conscientious, detail-oriented and organized, and interested in working independently.

Research Technician II, Cell Biology

FH Basic Sciences Division
Category: Laboratory Research Sciences
Seattle, WA, US
Job ID: 14147

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


A hallmark of many diseases and cancers is a dysfunctional cytoskeleton. A properly functioning cytoskeleton is needed for a wide variety of cellular events ranging from cell shape to cell signaling and migration/metastasis. The Parkhurst laboratory in the Basic Sciences Division at Fred Hutch uses multidisciplinary approaches to study these dynamic structural elements in various processes including wound repair and nuclear architecture/organization. Our goal is to understand the role of these elements in regulating normal developmental events and how this regulation goes awry in diseases/cancers, thereby providing new avenues for possible therapeutic targets or to enhance the effectiveness of existing treatment modalities.


Our current research efforts are divided among studies of: (1) Molecular and cellular mechanisms of single cell wound repair, and (2) Actin and microtubule cytoskeleton dynamics mediated by the Rho1 small GTPase and its effectors; and (3) Nuclear architecture and organization.

Responsibilities

  • The research technician will primarily carry out an independent research project that involves cell biology, developmental genetics, and molecular biology.
  • The technician will participate in lab meetings and journal clubs.
  • Other responsibilities include general lab maintenance (ordering, caring for Drosophila flies, fly media preparation), and other duties as needed.

This is an ideal position for a recent graduate who wants to gain an intense research experience before pursuing graduate and/or medical school.

Qualifications

  • A bachelor’s degree in a biological science and bench research experience are required.
  • Reliability is essential.
  • Good verbal and written communication skills.
  • Good interpersonal skills.
  • To be successful in this position, the technician must have scientific curiosity, a high level of self-motivation, the ability to take instruction and correction and to follow directions, good organizational skills, the ability to work and think independently, and wants to stay at least two years.
  • Must be able to distinguish different intensities and hues of red color.

Staff Scientist, Molecular and Behavioral Neuroscience

FH Basic Sciences Division
Category: Staff Scientist
Seattle, WA, US
Job ID: 12023

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
 
A highly motivated and experienced Staff Scientist is sought to carry out research in the laboratory of Dr. Linda Buck at Fred Hutchinson Cancer Research Center in Seattle, WA.

The Buck Lab studies the molecular mechanisms and neural circuits that underlie the sense of smell and instinctive odor responses. It is interested in how the olfactory system detects myriad environmental chemicals and how the brain translates those chemicals into diverse odor perceptions, hormonal alterations, and instinctive behaviors. Illumination of the neural circuits underpinning these and related effects may provide clues to those affected in certain human disorders, particularly those involving stress, fear, and appetite.

Responsibilities

  • Conduct research independently as well as contributing to research being done by other team members as needed
  • Research will focus on one or more research interests of the lab
  • Breed and genotype transgenic murine for specific projects
  • Prepare and analyze tissue sections for mRNA and protein expression using standard techniques utilized in the lab
  • Clone and analyze DNA for use as probes
  • Conduct experiments to analyze murine behavior
  • Prepare graphs and images of research results for presentation and publication
  • Present results obtained in group meetings

Qualifications

Minimum

  • PhD in molecular and cell biology or molecular neuroscience
  • At least five years of post-doctoral research experience
  • Excellent knowledge of fundamental molecular and cell biology
  • Experience using molecular techniques for cloning and for analysis of nucleic acids and proteins
  • Experience in murine breeding and genotyping
  • Experience in preparing tissue sections and analyzing them using immunohistochemistry and in situ hybridization


Preferred

  • Knowledge of neuroscience
  • Experience analyzing murine behavior
  • Experience with RNA sequencing and bioinformatics is a plus  

Systems Administrator

FH Basic Sciences Division
Category: Information Technology
Seattle, WA, US
Job ID: 14218

Overview

Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.


The System Administrator I is responsible for the installation, configuration, administration, maintenance, and support of computer hardware, software, and applications. The position’s responsibilities require independent analyses, communication and problem solving.

Responsibilities

  • Implement, install, configure, monitor, update, troubleshoot and evaluate existing and new computing and information systems
  • Provide end-user support, resolving technical issues
  • Provide technical assistance for all operating systems (PC, Mac and Ubuntu)
  • Assist with evaluating and recommending hardware and software
  • Develop and maintain installation and configuration procedures
  • Stay current with system information, changes and updates
  • Able to work well independently and as part of a team
  • Demonstrate critical thinking and problem-solving skills
  • Demonstrate excellent written and oral communication and customer service skills

Qualifications

  • Two years supporting a large number of users in a comparable systems environment
  • Bachelor’s degree or equivalent work experience

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