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A Phase 1-2 of ST316 With Selected Advanced Unresectable and Metastatic Solid Tumors
Complete Title: A Phase 1-2 Dose-escalation and Expansion Study of ST316 in Subjects with Selected Advanced Unresectable and Metastatic Solid Tumors
Trial Phase: I/II
Investigator: Gabriela Chiorean
This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept efficacy of ST316 administered IV in subjects with selected advanced solid tumors likely to harbor abnormalities of the WNT/ß-catenin signaling pathway. The study consists of two phases: a phase 1 dose escalation/regimen exploration phase and a phase 2 expansion phase.
Keywords:
- Colon Cancer
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