Clinical Trial Details

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients with Advanced Solid Tumours

Complete Title: A Phase 1, First-in-human, Multicentre, Open-label, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients with Advanced Solid Tumours
Trial Phase: I
Investigator: Delphine Chen

This is a first-in-human, Phase 1, non-randomized, multicenter, open-label clinical study designed to investigate the safety, tolerability, dosimetry, biodistribution, and pharmacokinetics (PK) of [225Ac]-FPI-2068, [111In]-FPI-2107, and FPI-2053 in metastatic and/or recurrent solid tumors (HNSCC, NSCLC, mCRC, PDAC).

Keywords:
  • Head and Neck Cancer; Pancreatic Cancer; Lung Carcinoma, Non-Small-Cell (NSCLC); Carcinoma, Squamous Cell; Colorectal Neoplasms; Advanced Solid Tumors
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