Simon S. Lo, MB, ChB, FACR, FASTRO

Simon S. Lo, MB, ChB, FACR, FASTRO
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Simon S. Lo, MB, ChB, FACR, FASTRO

  • Physician, Fred Hutch
  • Professor, Department of Radiation Oncology; Professor, Department of Neurological Surgery, University of Washington School of Medicine
  • Physician, UW Medicine

Radiation Oncology

“What I enjoy most about my practice is the opportunity to support patients and families so they don’t have to face cancer alone. ”

— Dr. Lo

What drew you to the field of radiation oncology?

I decided to become a physician because I wanted to help people who were facing acutely challenging medical situations. Radiation oncology suits me as a specialty because I am a very detail-oriented person, and there are many technical elements to coordinate when delivering this kind of treatment. I also really enjoy the multidisciplinary nature of this work — collaborating with so many different team members to cure cancer when possible and improve patients’ quality of life. What I enjoy most about my practice is the opportunity to support patients and families so they don’t have to face cancer alone.

What is your approach to care?

As your radiation oncologist, I will share all the options for treatment with you, and together we will weigh the pros and cons of each so that you can choose the best option for you. I make myself available to answer questions, and I’m always happy to provide and discuss data to support my recommendations. While I can’t guarantee a particular outcome, I can guarantee that we will deliver you the best possible care, which I view as evidence-based, compassionate and attentive.

Provider Background

Specialty: Radiation Oncology

Brain and spinal tumors, metastatic tumors

I am a board-certified radiation oncologist who specializes in the treatment and research of cancers affecting the central nervous system, which includes the brain and spine. I also provide care for patients with metastatic tumors (cancers that have spread to various sites throughout the body). My expertise includes a variety of treatment methods, including stereotactic radiation therapy, stereotactic radiosurgery and Gamma Knife. I am a fellow of the American College of Radiology, and I’ve published four books and more than 150 scientific articles pertaining to the field of radiation oncology.

In addition to patient care and research, I am involved in developing national clinical practice guidelines for stereotactic body radiotherapy as well as the treatment of brain and spinal tumors.

Diseases Treated

Brain and spinal cord cancers

Metastatic cancers



Education, Experience and Certifications

Medical Degree
The Chinese University of Hong Kong

University of Minnesota Medical School, Radiation Oncology; Queen Elizabeth Hospital, Hong Kong, Oncology

Kwong Wah Hospital, Hong Kong, Orthopaedics

Board Certification
Radiation Oncology, 2001, American Board of Radiology

Internship, Prince of Wales Hospital, Hong Kong


Seattle magazine's 2021 Top Doctors award
Dr. Lo has been recognized as a Top Doctor in this peer-nominated award multiple years in a row.

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch doctors. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your doctor can decide if a study is right for you.

Find a Clinical Trial Led by Dr. Lo


Many of our Fred Hutch doctors conduct ongoing research to improve standards of patient care. Their work is evaluated by other doctors and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch provider has written.

View Dr. Lo's Publications

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes doctors, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like nutritionists, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders.


Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

For the Media

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