Shreena Portillo, ARNP, FNP-C, MSN

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Shreena Portillo, ARNP, FNP-C, MSN

Shreena Portillo, ARNP, FNP-C, MSN

  • Advanced Registered Nurse Practitioner, Fred Hutch
  • Teaching Associate, University of Washington School of Medicine

“My goal is to be a source of comfort and be there for you throughout every step of your journey.”

— Shreena

How has cancer affected you personally?

My grandmother was diagnosed with cancer when I was a senior in high school. I remember feeling fear, guilt, love and sympathy, all at the same time. While the experience drew my family closer together, the doctors who cared for my grandmother didn’t do a good job of preparing us for her death. Going through that difficult time has made me very attuned to how I communicate with patients and families. Being honest, open and transparent is key. It’s important to me that you and your loved ones understand what we are doing medically and why we’re doing it.

What do you want patients to know about working with you?

My goal is to be a source of comfort and be there for you throughout every step of your journey. I am the kind of practitioner who listens intently to what you’re telling me about your experience versus focusing solely on what a physical exam demonstrates. I want to make sure we are working toward your personal goals as well as effectively addressing your symptoms. I believe that providing education and support and helping you maintain a high quality of life are critical to providing good patient-focused care.

Provider Background

Malignant and non-malignant blood disorders

I am an advanced registered nurse practitioner who specializes in treating patients with a range of malignant and non-malignant blood disorders. One primary area of interest is working with adults who have sickle cell disease. My background includes experience in pediatric hematology-oncology as well as thoracic medical oncology, which focuses on cancers of the lungs, chest and esophagus. Prior to joining SCCA, I provided care and conducted clinical research at H. Lee Moffitt Cancer Center & Research Institute.


Diseases Treated



Education, Experience and Certifications

Undergraduate Degree
University of Connecticut

Medical Degree
Simmons University

Board Certification
Advanced Registered Nurse Practitioner, 2018, American Association of Nurse Practitioners

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch doctors. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your doctor can decide if a study is right for you.

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes doctors, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like nutritionists, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders.


Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with providers.

Email or call 206.667.2210