Mazyar Shadman, MD, MPH

Mazyar Shadman, MD, MPH

Mazyar Shadman, MD, MPH

  • Physician, Fred Hutch
  • Associate Professor, Division of Medical Oncology, University of Washington School of Medicine
  • Associate Professor, Clinical Research Division, Fred Hutch
  • Innovators Network Endowed Chair, Fred Hutch

Medical Oncology

“Your positive attitude and willingness to fight have always inspired me.”

— Dr. Shadman

What do you enjoy about being an academic physician?

Every day, I get to integrate science with the art of human interaction. Seeing patients benefit from medical advances, and being active in pushing the science forward, is extremely rewarding. It’s an exciting time for both cancer care and research. We now have access to a variety of novel therapies that enable us to target cancer cells more specifically without causing major side effects. In my field, we’re always looking for a “cure,” but in the meantime, I’m hopeful that we can relegate cancer to a chronic disease and help patients maintain their desired quality of life.

What is your role in cancer treatment?

A diagnosis of cancer kicks off a torrent of life changes, and in the middle of all this disruption are many important decisions to make about your care. My role is to help you thoroughly understand and weigh your options. At Fred Hutch, you have access to a variety of standard and experimental treatments, from chemotherapy to more novel, targeted approaches that may have fewer side effects. We’ll discuss each option in detail — the potential benefits, the risks and the overall impact on your life and family — so that you can make the best choices for your unique situation.

Provider Background

Specialty: Medical Oncology

Area of clinical practice

Adult Blood and Marrow Transplantation, Cellular Immunotherapy, Hematologic Malignancies


I am a medical oncologist and stem-cell transplant expert who specializes in treating patients with lymphomas and other blood disorders. My clinical trial work focuses on testing novel agents for the treatment of leukemia and lymphoma, with a particular focus on chronic lymphocytic leukemia (CLL). I also study the clinical outcomes of patients who have already been treated. My goal is to identify patient- or disease-specific characteristics that can help us understand the behavior of a disease and predict its responsiveness to different treatments. One particular area of interest is the epidemiology of hematologic neoplasms (abnormal growth in blood-forming tissue). In 2013, I co-authored a study that found a correlation between certain types of allergies and blood cancers.

Diseases Treated

Chronic Lymphocytic Leukemia

Diffuse Large B-cell Lymphoma

Hodgkin Lymphoma


Mantle Cell Lymphoma

Non-Hodgkin Lymphoma

Cutaneous Lymphoma

Follicular Lymphoma

Low Grade Lymphoma

MALT Lymphoma

Marginal Zone Lymphoma

Waldenström Macroglobulinemia



Education, Experience and Certifications

Medical Degree
Tehran University of Medical Sciences

Cleveland Clinic Foundation, Internal Medicine

University of Washington, Hematology-Oncology

Board Certification
Medical Oncology, 2014; Hematology, 2014; Internal Medicine, 2011, American Board of Internal Medicine

MPH, University of Washington


All news
Blood cancer experts Drs. Roland Walter and Mazyar Shadman receive endowed chairs Chairs recognize innovation and contributions to blood cancer research July 12, 2023
Dr. Mazyar Shadman receives the 2021 Ali Al-Johani Award Oncologist lauded for his compassion and care for bone marrow transplant patients March 31, 2021

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch doctors. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your doctor can decide if a study is right for you.

Find a Clinical Trial Led by Dr. Shadman


Many of our Fred Hutch doctors conduct ongoing research to improve standards of patient care. Their work is evaluated by other doctors and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch provider has written.

View Dr. Shadman's Publications

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes doctors, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like nutritionists, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders.


Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with providers.

Email or call 206.667.2210