Matthew Triplette, MD, MPH

Matthew Triplette, MD, MPH

Matthew Triplette, MD, MPH

  • Medical Director, Lung Cancer Early Detection and Prevention Clinic, Fred Hutch
  • Associate Professor, Public Health Sciences Division, Fred Hutch
  • Associate Professor, Clinical Research Division, Fred Hutch
  • Associate Professor, Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington School of Medicine


“I believe that the safe, complex and state-of-the-art care that our patients deserve is most effectively delivered through a team-based approach.”

— Dr. Triplette

Why do you practice oncology?

Working in healthcare allows me to pursue a passion for science and discovery to improve overall population health for the future while also developing individual therapeutic relationships to help patients and families deal with disease with the best technology of today. Cancer patients and their families show the best of humanity. Their ability to face their illnesses with courage and dignity constantly inspires me. My primary research is to better understand how best to utilize lung cancer screening to save the most lives and make this an effective service for eligible patients. I also study lung disease and lung cancer in immune-suppressed patients, such as persons living with HIV, to understand unique risk factors in these populations. In the realm of lung cancer where we diagnose most cancers in advanced and incurable stages, I hope improvements in screening and detection lead to more early diagnoses and improved survival. Outside of work, I love spending time outdoors in and around Seattle. I enjoy hiking, biking, running and skiing. I love to travel (particularly for the food!) I also enjoy hanging out with my family and my pets.

Provider Background

Area of Clinical Practice

High risk prevention, thoracic cancers

Lung Cancer Early Detection

When I care for patients in the intensive care unit and in pulmonary clinics at the University of Washington and Fred Hutch, I am continuously amazed by our nurses, housestaff, advanced practice providers, technicians and other staff members who work together to provide comprehensive and compassionate care for our patients. My goal is to provide leadership in patient care worthy of their efforts.

Diseases Treated

Graft versus Host Disease

Lung Cancer



Education, Experience and Certifications

Medical Degree
University of North Carolina, Chapel Hill

University of California, San Francisco

University of Washington

Board Certification
Internal Medicine, 2014; Pulmonary Disease, 2017; Critical Care Medicine, 2018, American Board of Internal Medicine

MPH, University of North Carolina, Chapel Hill


Related News

All news
Question? Answers from our cancer experts Does growing up in a household with smokers qualify someone for a low-dose CT lung cancer screening? November 17, 2023
Don’t forget the F/U after your lung cancer screening Fred Hutch study finds nearly half of people with ‘positive’ lung cancer screening CTs had delays in their follow-up, advancing disease in some August 30, 2023

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch doctors. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your doctor can decide if a study is right for you.

Find a Clinical Trial Led by Dr. Triplette


Many of our Fred Hutch physicians conduct ongoing research to improve standards of patient care. Their work is evaluated by other physicians and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch physician has written. 

View Dr. Triplette's Publications

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes physicians, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like registered dietitians, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders. 


Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with providers.

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