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Triplette
Matthew Triplette, MD, MPH

Matthew Triplette, MD, MPH

Pulmonology

  • Medical Director, Lung Screening Program, Fred Hutch
  • Medical Director, Living Tobacco-Free Services, Fred Hutch
  • Associate Professor, Cancer Prevention Program, Public Health Sciences Division, Fred Hutch
  • Associate Professor, Clinical Research Division, Fred Hutch
  • Associate Professor, Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington School of Medicine
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About

Dr. Matthew Triplette is a board-certified pulmonologist and researcher at Fred Hutch. He provides critical and pulmonary care, while studying how lung cancer screening, early detection and disparities affect people at high risk for thoracic cancers.

Provider Background

Dr. Triplette provides patient care in intensive care units and pulmonary clinics, emphasizing compassionate, team based care. He is the medical director of both the Lung Cancer Screening Program and Living Tobacco-Free Services at Fred Hutch.

Alongside patient care, Dr. Triplette conducts research focused on how to implement lung cancer screening in ways that save the most lives. His studies examine barriers and facilitators to screening, as well as disparities that affect who is screened and diagnosed early. He also studies lung disease and lung cancer in underserved and at risk populations, including people who are immunosuppressed, such as those with HIV or who had a prior organ transplant.

Area of Clinical Practice
High risk prevention, thoracic cancers, lung cancer early detection

“I believe that the safe, complex and state-of-the-art care that our patients deserve is most effectively delivered through a team-based approach.”

— Dr. Triplette

Why do you practice oncology?

Working in healthcare allows me to pursue a passion for science and discovery to improve overall population health for the future while also developing individual therapeutic relationships to help patients and families deal with disease with the best technology of today. Cancer patients and their families show the best of humanity. Their ability to face their illnesses with courage and dignity constantly inspires me. My primary research is to better understand how best to utilize lung cancer screening to save the most lives and make this an effective service for eligible patients. I also study lung disease and lung cancer in immune-suppressed patients, such as persons living with HIV, to understand unique risk factors in these populations. In the realm of lung cancer where we diagnose most cancers in advanced and incurable stages, I hope improvements in screening and detection lead to more early diagnoses and improved survival. Outside of work, I love spending time outdoors in and around Seattle. I enjoy hiking, biking, running and skiing. I love to travel (particularly for the food!) I also enjoy hanging out with my family and my pets.

Diseases Treated

Graft versus Host Disease

Lung Cancer

COALS: Community-based Outcomes and Adherence for Lung cancer Screening

PEARLS: Patient Experiences with Adherence and navigation Resources in Lung cancer Screening

Dr. Triplette has studied racial disparities in coronary artery disease, chronic lung disease in HIV patients, and community-based screening for HIV and lung cancer. His current collaborative studies focus on lung cancer screening practices in underserved and at-risk populations. He is leading Fred Hutch and University of Washington's efforts to examine the current implementation of lung cancer screening and better understand barriers, facilitators and potential disparities in screening practices. He is part of an ongoing clinical study of biomarkers of lung-related disease and has an ongoing interest in lung cancer in special at-risk populations, including immunosuppressed patients with HIV or prior organ transplant.

Languages

English

Education and Experience

Fellowship, Pulmonary and Critical Care Medicine, University of Washington

Graduate Studies, Epidemiology, University of Washington

Residency, Internal Medicine, University of California, San Francisco

MD, University of North Carolina, Chapel Hill

MPH, Health Care and Prevention, University of North Carolina, Chapel Hill

Board Certifications

Critical Care Medicine, 2018; Pulmonary Disease, 2017; Internal Medicine, 2014; American Board of Internal Medicine

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch physicians and researchers. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your physician can decide if a study is right for you. 

Find a Clinical Trial Led by Dr. Triplette

Publications

Many of our Fred Hutch physicians and researchers conduct ongoing research to improve standards of patient care. Their work is evaluated by other physicians and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch physician has written. 

View Dr. Triplette's Publications

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes physicians, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like registered dietitians, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders. 

Meet Other Providers

Insurance

Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

More About Insurance

Stories

All news
Lung Cancer Awareness Month: Progress in early screening and diagnostics, plus smoking cessation programs to help reduce health disparities
Lung Cancer Awareness Month: Progress in early screening and diagnostics, plus smoking cessation programs to help reduce health disparities October 24, 2023
Are we ready for multi-cancer detection tests?
Are we ready for multi-cancer detection tests? Blood-based cancer tests are coming, but questions about efficacy, reimbursement and diagnostic pathways are far from settled September 22, 2025
Question? Answers from our cancer experts
Question? Answers from our cancer experts Does growing up in a household with smokers qualify someone for a low-dose CT lung cancer screening? November 17, 2023

Contact Information

206.667.6335

206.667.5765