/content/dam/www/people-profile-photos/h/eric-holland/eric-holland-d.jpg
Holland
Eric Holland, MD, PhD

Eric Holland, MD, PhD

  • Senior Vice President and Director, Human Biology Division, Fred Hutch
  • Member, Immunotherapy Integrated Research Center (IIRC), Fred Hutch
  • Pigott Family Endowed Chair, Fred Hutch
  • Director, Seattle Translational Tumor Research, Fred Hutch, UW Medicine & Seattle Children's
206.667.6117
206.667.6022

Background

Dr. Eric Holland is a world-renowned physician-scientist who combines compassionate patient care with exacting laboratory research to discover more effective treatments for brain tumors. As a neurosurgeon, Dr. Holland specializes in caring for patients with glioblastomas, aggressive cancers that are the most common malignant brain tumors in adults. One of Dr. Holland’s many accomplishments is the development of mouse models of brain cancers, which researchers use to unravel tumor biology and test new therapies. His landmark work with mouse models also revealed that glioblastoma is not one but several diseases, a finding that is a first step toward tailoring treatment to individual tumors. Dr. Holland also studies the environment immediately surrounding tumor cells and how that “neighborhood” influences tumor formation and growth.

Education

Stanford University, 1990, MD

University of Chicago, 1985, PhD (Biochemistry and Molecular Biology)

Research Interests

Dr. Holland's research has centered around the development of genetically accurate mouse models of gliomas. He has used them to study the biology of these tumors, the way that they respond to current therapy, and the development of new methods for treating them.

"The molecular field is a great place to be because that’s where the most interesting and striking advances—the cool stuff—has happened over the last 20 years."

— Dr. Eric Holland

Find a Clinical Trial Led by Dr. Holland

Stories

All news
Fred Hutch collaboration reveals molecular vulnerability in rare childhood brain cancer Researchers uncover a weak link in tumors driven by a notorious gene fusion that could be targeted with a drug March 16, 2026
Brandeis University honors Fred Hutch molecular biologist Dr. Steven Henikoff receives 55th Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research October 30, 2025
New methods reveal cancer mechanism in ancient genes Fred Hutch researchers discover that overproduction of DNA packaging material predicts aggressive brain and breast tumors, which could lead to cheaper diagnostic tests and new drug therapies March 3, 2025