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Corey
Larry Corey, MD

Larry Corey, MD

Infectious Disease

  • Physician, Fred Hutch
  • President and Director Emeritus, Fred Hutch
  • Professor, Infectious Disease Sciences Program, Vaccine and Infectious Disease Division, Fred Hutch
  • Professor, Clinical Research Division, Fred Hutch
  • Professor, Public Health Sciences Division, Fred Hutch
  • Member, Pathogen-Associated Malignancies Integrated Research Center (PAM IRC), Fred Hutch
  • Principal Investigator, HIV Vaccine Trials Network (HVTN)
  • Professor, Medicine and Laboratory Medicine, UW Medicine
  • Professor, Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington School of Medicine

About

Dr. Larry Corey is a board-certified physician and researcher whose expertise is in infectious diseases at Fred Hutch. He leads global research on viral infections, immune responses and vaccine development.


Background

Dr. Corey is an internationally renowned expert in virology, immunology and vaccine development, and the former president and director of Fred Hutch. His work focuses on preventing and treating viral infections, particularly in people affected by cancer or have weakened immune systems. His clinical and research interests span herpes viruses, HIV, the novel coronavirus and other viral infections that can cause serious disease.

Dr. Corey is the principal investigator of the HIV Vaccine Trials Network (HVTN), an international research program that conducts HIV vaccine studies at more than 80 clinical trial sites across 16 countries on five continents. Under his leadership, the HVTN has become a model for large-scale, collaborative global research. He is also the principal investigator of the Fred Hutch–based operations center of the COVID-19 Prevention Network (CoVPN) and co-leads the network’s vaccine testing pipeline.

In his lab, Dr. Corey studies how immune cells control herpes simplex virus, with the goal of developing vaccines that reduce viral reactivation. In the early 1980s, he worked with future Nobel laureate Dr. Gertrude Elion on the development of acyclovir, the first effective treatment for genital herpes. Then as director of the AIDS Clinical Trials Group, he helped lead research that proved combination antiretroviral therapy could control HIV and reduce transmission from mothers to infants. His research also demonstrated the importance of early treatment by showing that HIV replicates in the blood early in infection.

Area of Clinical Practice
Infectious disease


"There is nothing that has impacted the lives of more people than antivirals, especially those for HIV."

— Dr. Corey


Virology

Viral immunology

Development of novel therapies for viral infections

HIV and herpesvirus vaccine development

Herpes simplex virus type 2 (HSV-2) pathogenesis and the host immune response

Immunotherapeutic approaches to viral infections and cancer

Spatial and functional characterization of tissue resident immune responses at the site of herpesvirus or HIV infection

Development of immunotherapies for HSV and HIV infection; including CAR T cells for treatment for HIV infection

Spatial dynamics and function of adoptively transferred or vaccine induced T cells

Characterization of tissue-based memory B cells and the role antibody effector responses play in chronic viral infections

Use of monoclonal antibodies for the prevention of viral infections

Languages

English

Education and Experience

Residency, Internal Medicine, University of Michigan Medical Center

MD, University of Michigan Medical School

BS, University of Michigan (with High Distinction)

Board Certification

Internal Medicine, 1974, American Board of Internal Medicine

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch physicians and researchers. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your physician can decide if a study is right for you.

View Clinical Trials

Publications

Many of our Fred Hutch physicians and researchers conduct ongoing research to improve standards of patient care. Their work is evaluated by others in their field and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch physician has written.

View Dr. Corey's Publications

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes physicians, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like registered dietitians, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders. 

Insurance

Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

Stories

All news
The benefits of HIV research? Let us count the ways HIV work has helped shape the FDA, provided drugs for other infections, changed health systems globally and more, say Fred Hutch experts November 28, 2025
Infectious disease experts propose trials network dedicated to immunocompromised patients ImmunOptimize workshop convened stakeholders across disciplines to brainstorm infectious disease clinical trials network designed to serve people with weakened immune systems October 21, 2024
2022 Year in Review A look at the most interesting and important stories of the past year December 12, 2022

Contact Information

206.667.6770

206.667.1188