It ends with her

An inherited gene mutation upended Amanda Swenson’s life. She gives to ensure her daughter has a healthier future
mother and daughter
Amanda Swenson (right) shares her mother’s love for family and crafting. Courtesy of Amanda Swenson

When Amanda Swenson met Fred Hutch Cancer Center researcher Richard Adeyemi, DVM, PhD, in spring 2025, she got goosebumps. Multiple times. 

Adeyemi is an assistant professor in Fred Hutch’s Basic Sciences Division, and Swenson clocked his genius immediately as they talked in his lab. Then there was his quiet confidence, which revealed itself a little more slowly. More than anything else, though, she was struck by Adeyemi’s exciting ideas for fixing the very genetic trait that had upended her life — and decided right then and there that she wanted to support him and his work. 

Adeyemi studies the BRCA2 gene. When it works as intended, BRCA2 plays a crucial role in correcting damage to our DNA. When it doesn’t, the individual’s risk of several cancers jumps significantly. Swenson inherited a BRCA2 mutation and was diagnosed with breast cancer in her late 30s.

Like others in the Basic Sciences Division, Adeyemi is working to answer fundamental questions about our cells and how they work so we can better understand what causes diseases like cancer. He and his colleagues have discovered that while a BRCA2 mutation can drive cancer, it also creates vulnerabilities in tumor cells. In his lab, as he explained his ideas for exploiting those weaknesses, Swenson thought, “Yes, this is exactly what we need to do. And Dr. Adeyemi is the guy for the job.”

Swenson learned about her BRCA2 status in her late 20s when her mom was diagnosed with pancreatic cancer, and they both underwent genetic testing. Equipped with that invaluable knowledge, Swenson started getting mammograms right away, more than a decade before national guidelines recommend them for individuals at average risk. 

She knew the odds: Her risk of breast cancer was nearly five times higher than that of someone without an inherited BRCA mutation. So it wasn’t exactly shocking when, at 37, one of Swenson’s semi-annual screenings at Fred Hutch detected a mass. But that didn’t make it any less traumatic — for Swenson or for her family. She was especially worried about her young daughter; what if she had inherited the mutation from Swenson, just as Swenson had from her mother? 

Swenson’s cancer was detected early, and her treatment was successful. When she felt she was physically and emotionally past the experience, she was motivated to do something to change the future for her daughter. 

“My mom died two years before I got my own cancer diagnosis,” Swenson said. “I truly wish I could have thanked her for the gift of early detection that she gave me. So instead, I’m going to pay it forward.”

‘A real opportunity to make an impact’

There was only one place Swenson even considered directing her newfound philanthropic intent. The staff and physicians at Fred Hutch’s Women’s Wellness Program had taken excellent care of her for years before her diagnosis, making sure she received the right screenings at the right time and connecting her with genetic counselors and registered dietitians. Then, when she needed treatment, they seamlessly transitioned her to the oncology team. So, not knowing exactly what to do next, she cold-called the Philanthropy Department, and a team member invited her to Fred Hutch’s South Lake Union campus for a lab tour. 

Her desire to support Fred Hutch research was about more than simply giving back. She was determined to effect real, measurable change. 

“I want my daughter’s experience to be drastically different than mine, and that can only come through big swings,” Swenson said. “And it felt like at Fred Hutch, there was this real opportunity to make an impact.”

Meeting with Adeyemi in 2025 further drove that point home — particularly because of the  compassion and sensitivity that he brings to his research. At various points in her life, Swenson has viewed her BRCA2 mutation as a deficiency and felt guilty about the possibility of passing it on to her daughter, “even though I had no choice in the matter and it’s just how I am,” she said. “But the way [Adeyemi] approaches [these genetic mutations] just feels so respectful to me as a human.”

Amanda Swenson and daughter
Amanda Swenson gives to create a healthier future for her daughter’s generation. Photo courtesy of Amanda Swenson

‘This is the future I want for my daughter’

Swenson was so inspired by what she learned in Adeyemi’s lab, she made her first gift to fund his research two weeks later, via her Donor-Advised Fund (DAF). Then, one year later, she made another. But she still wanted to do more to support him, as well as others like herself: younger, philanthropically minded and uniquely motivated to act. Which makes her an ideal addition to Innovators Network, Fred Hutch’s community of next-generation donors committed to ending cancer in their lifetime. 

What is a DAF?

A Donor-Advised Fund is a charitable giving account that lets donors make tax-deductible contributions that can be granted to nonprofit organizations over time. The funds can be invested and grow tax-free, offering flexibility in when and how donations are made. It’s a simple, cost-effective alternative to setting up a private foundation. DAFs are managed by sponsoring organizations, such as community foundations or financial institutions. Learn more or give via your DAF on our website.

“This was an opportunity for me to step out into the light to say, “This can happen, but we can move forward and make it better,” Swenson said. “If my story resonates with other people and would inspire them to give, it’s a no-brainer to share it.”

Last Friday, Swenson spoke with Adeyemi at IN for the Hutch, IN’s annual fundraiser, and rallied attendees to support the fundamental science that can drive new breakthroughs. 

“Basic science researchers like Richard are making the discoveries that could make what I went through look like ancient history,” Swenson said from the stage. “This is the future I want for my daughter and her whole generation.”

In that future, Swenson can focus more on all the good things she inherited from her mother, like devotion to family and a love of crafting.

“My mom was so wonderful, and she was so excited to be a grandmother,” Swenson said. “The love that I know how to give my daughter is because she loved me so well.”

Donor - Heart of the Hutch

About our Heart of the Hutch series

Much of Fred Hutch’s lifesaving research is possible because of the generosity of its supporters, who continually use their creativity and resourcefulness to raise money for research to prevent and treat cancer and other diseases.

This series highlights just a few of the thousands of Fred Hutch supporters who are the Heart of the Hutch.

Matthew Halverson

Matthew Halverson is a senior writer on the Philanthropy team at Fred Hutch Cancer Center who worked for two decades as an editor and writer at city and regional magazines, including Seattle Met. His byline has appeared in Conde Nast Traveler and Southwest Airlines magazine. Reach him at mhalver2@fredhutch.org.

Related News

All news
FDA approves new breast cancer drug based on VIKTORIA-1 study results New targeted drug brings ‘big change, big benefit,’ per Fred Hutch’s Dr. Sara Hurvitz, who led the study July 16, 2026
Testing for hereditary cancers can be a lifesaver Some people aren’t ready yet, while others believe ‘forewarned is forearmed’ when it comes to cancer-causing genetic variants September 29, 2025
Now’s the time to discuss family health history A Fred Hutch genetic counselor shares insights about her work, gives advice on how to start conversations December 17, 2024

Help Us Eliminate Cancer

Every dollar counts. Please support lifesaving research today.