Associate Professor
Vaccine and Infectious Disease Division, Fred Hutch
Dr. Justin Taylor is an immunologist who focuses his research on B cells, a type of white blood cell responsible for producing immune proteins called antibodies. He works with so-called naïve B cells, ones that have not yet been exposed to foreign or abnormal molecules — contact with which can trigger B cells to produce protective antibodies. His lab studies a complicated process that is required to produce both long-lived antibodies and a fleet of “memory” B cells that can respond to future contact with the same foreign molecules and thus protect against them. Dr. Taylor has developed tools to screen vaccine components rapidly to find whether they can bind to B cells in the first place, a relatively rare connection that is essential for a successful vaccine. This technique may be helpful in isolating components that might work in vaccines that have been particularly difficult to develop, such as one to block HIV.
Affiliate Assistant Professor, Department of Global Health
University of Washington
Affiliate Assistant Professor, Department of Immunology
University of Washington
Faculty Member, Interdisciplinary Program in Pathobiology
University of Washington
Faculty Member, Molecular & Cellular Biology Program
University of Washington
Ph.D., Immunology, University of Pennsylvania, 2008
B.S., Biology, Rider University, 2002
Mechanisms driving the differentiation of B cells following vaccination and infection
Understanding how differences in the pre-immune repertoire influences immunity
Vaccine development
Memory B cell differentiation and survival
Understanding diversity in naïve antigen-specific B cell populations
Identifying B cells specific for foreign and self antigens
B cell engineering
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