Jhimmy Talbot, Ph.D.

Faculty Member

Jhimmy Talbot, Ph.D.

Assistant Professor
Basic Sciences Division

Mail Stop: A2-025

Dr. Jhimmy Talbot studies how interactions between neurons and immune cells in the gut can help the body balance its immune and metabolic trade-offs. The gut balances two competing needs: bringing nutrients in and keeping pathogens out. Talbot showed that in the presence of food, certain gut neurons can increase nutrient absorption by reining in the activity of a specialized subset of immune cells that act to increase the gut wall’s barrier function by decreasing its permeability. His work reveals how changes in the diet or in the intestinal microbiota may lead to metabolic dysfunction and how neuroimmune interactions could be hijacked by microbes to enable infection. 

Education

Universidade de Sao Paulo, 2015, Ph.D.

Universidade de Sao Paulo, 2015, M.Sc.

Universidade Estadual de Santa Cruz, 2009, B.S. Biomedicine

Research Interests

Neuroimmunology: role in intestinal homeostasis

Enteric nervous system control of immunity and metabolism

Neuronal control of host-microbiota interactions in the gut

Neuronal mediated integration of distinct organ functions

Neuronal and immunologic basis of intestinal dysfunctions present in inflammatory bowel disease, irritable bowel syndrome and diabetes

Find a Clinical Trial

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with faculty.

Email media@fredhutch.org or call 206.667.2210.