Basic Sciences Division, Fred Hutch
Dr. Barry Stoddard is an expert in protein structure and engineering. He uses cutting-edge laboratory and computational techniques to reveal proteins’ 3D forms at the atomic level, which is key to his ultimate goal: modifying natural proteins to treat or cure human diseases. In particular, his group has made major contributions to the understanding of gene-targeting proteins, from determining their structure to creating variants for use in gene therapy. Dr. Stoddard’s work could lead to engineered proteins that are capable of correcting mutations that underlie genetic diseases like cystic fibrosis, and he’s working on proteins that could cure HIV and other chronic infections.
Affiliate Professor, Biochemistry
University of Washington School of Medicine
NCI Interdisciplinary Training Program in Cancer
Ph.D., Biophysical Chemistry, Massachusetts Institute of Technology, 1990
B.S., Chemistry/Biology, Whitman College, 1985
The structure, mechanism, and engineering of proteins and enzymatic catalysts for basic research and biomedical applications
Research on gene-specific endonucleases, nucleic acid enzymes, structural enzymology and protein engineering
— Dr. Barry Stoddard
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