Leonidas Stamatatos, Ph.D.

faculty member

Leonidas Stamatatos, Ph.D.

Vaccine and Infectious Disease Division, Fred Hutch

Fax: 206.667.7767
Mailstop: E5-110

Dr. Leonidas “Leo” Stamatatos and his team of researchers explore how antibody-producing B cells respond to infection and vaccination. Using diverse experimental approaches, the researchers also design and test ways to stimulate B cells into producing the antibodies deemed most likely to succeed against a chosen virus. Much of the work focuses on getting B cells to make antibodies that can provide sustained protection against HIV, which is adept at evading conventional vaccines through rapid genetic mutation. The group’s work encompasses the many stages in the development of candidate vaccines. These range from early, basic research on the structure of antibodies and their targets to detailed evaluation of the level of protection they provide to human volunteers in clinical trials.

Other Appointments & Affiliations

Affiliate Professor, Department of Global Health
University of Washington


B.A., Biochemistry, Université d’Orleans, France, 1982

M.Sc., Organic Chemistry, Université de Paris XI, France, 1983

Ph.D., Biochemistry, McGill University, Canada, 1988

Current Projects

Development of immunogens to elicit HIV protective antibody responses

Clinical evaluation of HIV vaccines

Comparison of immune responses to infection and vaccination by infants and adults

Find A Clinical Trial

Dr. Stamatatos in the News

Wild-type vs. modification: which is better?

Science Spotlight - August 20, 2018

Good News at Fred Hutch

Hutch News - October 15, 2015

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with faculty.

Email media@fredhutch.org or call 206.667.2210