Clinical Research Division, Fred Hutch
Dr. Lev Silberstein studies factors that regulate the behavior of normal and malignant stem cells in the bone marrow. He and his colleagues aim to develop new ways to boost blood cell production in patients with blood disorders, inherited bone marrow failure and those recovering from blood stem cell transplants.
Seattle Cancer Care Alliance
Assistant Professor of Medicine
University of Washington
M.D., Novosibirsk Medical Institute
M.B.B.S. equivalent, King’s College School of Medicine and Dentistry, London (UK)
Ph.D., University of Cambridge (UK)
Micro-environmental control of hematopoietic stem/progenitor quiescence
Restoration of hematopoietic stem cell function in bone marrow failure
Development of therapeutic strategies to enhance post-transplant reconstitution
Characterization of novel extrinsic regulators of hematopoietic stem cell/progenitor quiescence
Pharmacological modulation of hematopoietic stem cell quiescence to restore hematopoiesis in myelodysplasia (funded by Leukemia and Lymphoma Society Translational Research Program Award)
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