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Keith Jerome, M.D., Ph.D.

faculty member

Keith Jerome, M.D., Ph.D.

Vaccine and Infectious Disease Division, Fred Hutch

Fax: 206.667.6179
Mail Stop: E5-110

Dr. Keith Jerome is a renowned virologist whose research focuses on viruses such as herpes simplex, HIV and hepatitis B that persist in their hosts. He studies the ways in which these viruses evade the immune system and potential therapies for these infections. Dr. Jerome and his colleagues are studying the uses of precision gene-editing tools like CRISPR/Cas9 to remove damaging viral genes that have tucked themselves into a person’s genetic code or to insert genes that can protect cells from invading viruses. He and his colleagues are exploring this approach in combination with blood stem cell transplants as a means of curing HIV. Dr. Jerome also studies the coronavirus that causes COVID-19. He and his University of Washington colleagues developed a diagnostic test for infection with the coronavirus that expanded local testing capacity, and his Fred Hutch laboratory aims to validate and deliver COVID-19 tests that could diagnose infection within minutes.

Other Appointments & Affiliations

Professor, Department of Laboratory Medicine & Pathology
University of Washington

Head, Virology Division
University of Washington

Director, Molecular Virology Laboratory, Laboratory Medicine
University of Washington


M.D., Duke University, 1993

Ph.D., Immunology, Duke University, 1992

B.S., Chemistry, Georgetown College, 1985

Current Projects

Novel proteins (CRISPR/Cas9 and meganucleases) as potential treatments for HIV, hepatitis B, and herpes simplex infections

Diagnostics for viruses posing the greatest threat to human health

In vivo delivery of gene therapy for HIV and other persistent viral infections

Hepatitis B Research Network Central Lab

Find A Clinical Trial

Dr. Jerome in the News

Discovering potential emerging SARS-CoV-2 variants

Science Spotlight - April 18, 2022

A year of research dominated by the coronavirus

Hutch News - December 21, 2020

Fearless Science is ...

Hutch News - November 30, 2020

Suppressing immunity to fight HIV infection

Science Spotlight - November 16, 2020

COVID-19 Research at the Hutch

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with faculty.

Email or call 206.667.2210