Stephen De Rosa, MD
Associate Professor, Immunology and Vaccine Development Program
Vaccine and Infectious Disease Division, Fred Hutch
Dr. Stephen De Rosa develops assays to characterize our immune responses to vaccination against pathogens including HIV, tuberculosis, SARS-CoV-2 and malaria. In particular, he develops, optimizes and validates flow cytometry-based assays that detect whether a vaccine triggers responses from T and B cells, critical immune cells that can be engaged by a vaccine to protect against future infection and disease. These assays are essential to assessing a vaccine’s protective potential, and De Rosa’s work supports large vaccine trial networks, including the HIV Vaccine Trials Network (HVTN), that test vaccines around the globe.
Other Appointments & Affiliations
Research Professor, Division of Virology, Department of Laboratory Medicine and Pathology, University of Washington School of MedicineResearch Professor, Division of Virology, Department of Laboratory Medicine and Pathology
University of Washington School of Medicine
Education
MD, Stanford University, 1990
BS, Columbia Universtiy School of Engineering & Applied Sciences, 1983
Research Focus
Immunology of HIV, SARS-CoV-2, malaria, turbulosis related to vaccination; flow cytometry as a tool to characterize antigen-specific T and B cells and other immune cells
Current Projects
Cellular immunity characterization in HIV Vaccine Trials Network (HVTN) clinical trials; providing immunological consultation through the UW/Fred Hutch Center for AIDS Research (CFAR).
“An effective vaccine for HIV remains the best hope for protection from HIV globally. Although HIV vaccines are extraordinarily difficult, there is progress being made and we remain committed to the goal of finding a vaccine for HIV.”
— Dr. Stephen De Rosa