Jesse Bloom, Ph.D.


Jesse Bloom, Ph.D.

Associate Professor
Basic Sciences Division, Fred Hutch

Associate Professor
Public Health Sciences Division, Fred Hutch

Fax: 206.667.3331
Mail Stop: A3-020

Dr. Jesse Bloom studies evolution using viruses and viral proteins as models. Specifically focusing on the fast-evolving influenza virus, Bloom aims to understand how mutations in viral genes shape the pathogen’s ability to infect and spread. He uses computational biology and real-world data to build evolutionary models and examine different scales of viral evolution, from evolution within a single host to evolution on a global scale. In doing so, Bloom addresses both fundamental and translational questions, including those with relevance to developing more effective seasonal flu vaccines.

Other Appointments & Affiliations

Howard Hughes Medical Institute Investigator
Howard Hughes Medical Institute


Postdoc in Biology, Caltech

Ph.D. in Chemistry, Caltech

M.Phil. in Theoretical Chemistry, Cambridge

B.S. in Biochemistry, University of Chicago


“We don’t really understand why certain viruses are so good at escaping from our vaccines while others aren’t. We would like to better understand the constraints of evolution.”

— Dr. Jesse Bloom

Find a Clinical Trial

Dr. Bloom in the News

Probing the evolution of Influenza at high resolution

Science Spotlight - September 20, 2020

How COVID-19 has opened science

Hutch News - September 15, 2020

Antibodies a hot topic in COVID-19 research

Hutch News - June 24, 2020

Mixing antibodies in silico: is more better?

Science Spotlight - June 15, 2020

COVID-19 Research at the Hutch

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with faculty.

Email or call 206.667.2210.