Rigor, Reproducibility and Transparency Training Program

Rigor, Reproducibility and Transparency Seminar Series

The Rigor, Reproducibility, and Transparency (RRT) Seminar Series is a series in collaboration with the University of Washington presented by faculty from each of the several ongoing training grants at Fred Hutch and UW. The series is in response to recently mandated RRT training by the NIH for trainees on training grants, F awards, and K awards. Lectures focus on a detailed discussion of common or emerging methodologies with the aim of describing strengths, limitations, and pitfalls so those employing or interpreting the data gain a realistic sense of what can and cannot be learned. Trainees are encouraged to attend lectures outside of their field of expertise as it is likely that they will encounter data from these methods, and understanding how they work and what their limitations are is crucial, so the talks are designed to be accessible to a broad biomedical audience.

Who is required to attend the series?

All trainees on training grants should check with their training grant director for required attendance, and F & K awardees are strongly encouraged to participate. 

How to participate

The RRT seminar series will be held every 2 months. There are 2 ways to receive credit for participation:

1. Attend the seminar live

2. Watch the video recording of the seminar within 30 days

After attending live or viewing the recording, attendees will fill out a survey and state 3 things learned.

Upcoming Seminar

Chip Asbury, PhD

May 9, 2023, 2 PM


Seminar Series

Jesse Zalatan, PhD

March 7, 2023, 2 PM - From negative results to new insights in cell signaling and gene regulation


Sam Minot, PhD

February 21, 2023, 2 PM - Practical reproducibility in bioinformatics – opportunities, pitfalls, and useful strategies


Evan Newell, PhD

December 6, 2022, 2 PM - High dimensional analysis of human T cells in health and disease


Jing Ma, PhD

October 25, 2022, 2 PM - Statistical methods to enhance reproducible microbiome discovery 


Suzanne Hoppins, PhD

May 3, 2022, 2 PM - The reconstitution of mitochondrial fusion


Andrew Oberst, PhD

March 8, 2022, 2 PM - Effective use of mouse models for biological research


Larry Zweifel, PhD

January 18, 2022, 2 PM - Rigor and reproducibility in targeting gene function using viral-mediated CRISPR/Cas9 mutagenesis


Alice Berger, PhD

October 12, 2021, 2 PM - On-Target Discovery: Rigor and reproducibility in genetic screens


Stefan Stoll, PhD

September 28, 2021, 2 PM - Protein Conformational Changes: Using Bayesian Inference to Quantify Uncertainty and Make Robust Conclusions


Joshua Vaughan, PhD

May 4, 2021, 2 PM - Rigor and Reproducibility in Optical Microscopy


Miklos Guttman, PhD

March 23, 2021, 2 PM - Overcoming irreproducibility in hydrogen/deuterium exchange studies: Establishing rigor and reproducibility in a technique approaching its adolescence


Ruth Etzioni, PhD

January 12, 2021, 2 PM - Getting the numbers right - common statistical misses in the news and in the lab


Lucas Sullivan, PhD

November 17, 2020, 2 PM - Rigor and Reproducibility in Metabolomics


Chetan Seshadri, MD

September 15, 2020, 10 AM - Rigor and Reproducibility in Flow Cytometry


Jesse Bloom, PhD

July 16, 2020, 2 PM - Studying the impacts of mutations to SARS-CoV-2


Andrea Wills, PhD

May 14, 2020, 1 PM - Querying chromatin accessibility in complex tissues with ATAC-Seq

Amber Ismael, PhD

Senior Program Manager, Office of Scientific Career Development

Karen Peterson, PhD

Director, Office of Scientific Career Development