Acute promyelocytic leukemia (APL) is a rare subtype of acute myeloid leukemia (AML). It develops when immature white blood cells called promyelocytes build up in the bone marrow and blood.

APL is considered a medical emergency. That’s because it can cause serious bleeding problems. Early diagnosis and prompt treatment are important.

Acute Promyelocytic Leukemia Care Tailored to You

You and your family are our top priority. At Fred Hutch Cancer Center, we offer comprehensive and compassionate care — personalized to you. You'll have access to the latest treatment options, clinical trials and supportive care services.

APL Treatment

Unlike other forms of AML, APL treatment targets the specific genetic change responsible for the disease. This treatment often includes targeted medicines used together with other therapies. Throughout treatment, your Fred Hutch care team closely monitors your health and response to therapy.

Because APL responds differently than other AML subtypes, early treatment can lead to better outcomes for many people. Learn about specific therapies for APL.