Natalie F. Uy, MD

Natalie F. Uy, MD

Natalie F. Uy, MD

  • Physician, Fred Hutch
  • Clinical Assistant Professor, Division of Hematology and Oncology, University of Washington School of Medicine


“As an oncologist, I provide information to patients to help them make treatment decisions that best fit their goals. I tell patients we are guides to help navigate the cancer journey, and it's an honor to care for patients and families during a very challenging time.”

— Dr. Uy

What brought you to oncology?

My first experience with cancer was teaching art therapy at my university cancer center. In medical school, cancer became personal when my uncle was diagnosed with leukemia, which was overwhelming for my family. This inspired me to pursue hematology-oncology, as I wanted to help cancer patients and families in a time of need.

How would you describe your approach to care?

In a rapidly changing field with new therapies, my goal is to guide patients through their cancer care. My philosophy is to engage in shared decision-making, practice evidence-based medicine, and help advance cancer treatments with access to research and clinical trials for patients.

Do you have any favorite memories from working with patients you’d like to share?

My favorite memories are the "small talk" with patients and developing close relationships. I love getting to know patient's pets (from African grey parrots to goats to German shepherds), how they meet their spouse (a bar fight in the Vietnam War), their hobbies, their celebrations (starting vanlife after beating cancer) and more.  During the cancer journey, that human connection is so important.

Provider Background

I am a hematologist-oncologist who sees patients at Fred Hutch at EvergreenHealth.

I am trained to treat a variety of hematology and oncology diseases, and my focus is on lung, head and neck cancer. I am particularly interested in targeted therapy and understanding driver mutations as a more personalized way to treat patients with cancer. I have done research on lung, head and neck cancer, as well as quality of life and supportive care, that has been presented at national oncology conferences and published in oncology journals.

We do all we can to help our patients get the best possible care. We bring research programs to the community, so our patients have access to clinical trials and new treatments. I truly believe this is the best place for cancer care.

Community Oncology

Our mission is to provide patients with the highest quality, personalized care closer to home. As part of Fred Hutch, our community oncologists offer patients multidisciplinary tumor board opinions, clinical trials and expertise in treating a variety of cancers.



Education, Experience and Certifications

Undergraduate Degree
Stanford University 

Medical Degree
Baylor College of Medicine 

Yale University, Internal Medicine

University of Washington, Hematology-Oncology

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch physicians. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your physician can decide if a study is right for you.

View Clinical Trials


Many of our Fred Hutch physicians conduct ongoing research to improve standards of patient care. Their work is evaluated by other physicians and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch physician has written.

View Dr. Uy's Publications

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes physicians, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like registered dietitians, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders.


Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with providers.

Email or call 206.667.2210