David G. Maloney, MD, PhD

David G. Maloney, MD, PhD
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David G. Maloney, MD, PhD

  • Medical Director, Cellular Immunotherapy and Bezos Family Immunotherapy Clinic, Fred Hutch
  • Professor and Medical Director Cellular Immunotherapy, Translational Science and Therapeutics Division, Fred Hutch
  • Leonard and Norma Klorfine Endowed Chair for Clinical Research, Fred Hutch
  • Professor of Medicine, Division of Hematology and Oncology, University of Washington School of Medicine

Medical Oncology

“It’s not enough to treat cancer — we want to rev up your immune system to cure it.”

— Dr. Maloney

Why do you conduct research?

When I was a student at Stanford University in the 1980s, I was part of a team that made an amazing discovery. We created a protein called a monoclonal antibody that targeted cancer cells without harming healthy ones. At the time, there were a lot of skeptics — most people thought that antibody research wasn’t worthwhile. But we persevered, and now monoclonal antibodies are an important part of therapy for a variety of cancers. That breakthrough made me hungry for more. What else could I discover about the immune system? Could we train it to go after tumors the same way it attacks viruses? Does it hold the key for curing cancer, once and for all? These are the questions that have driven my work.

How do you approach cancer treatment?

A treatment plan isn’t something that we devise in one short discussion. It’s an in-depth conversation that may stretch across multiple visits. We’ll consider factors such as your health, your age, your disease, your personal philosophy and what the latest research has to offer. Treatments are rapidly evolving, and I enjoy sharing these advances with you so that you can make the best decisions about your care. Whatever you choose, I’m dedicated to helping you achieve the best possible outcome.

Diseases Treated

Chronic Lymphocytic Leukemia

Diffuse Large B-cell Lymphoma

Hodgkin Lymphoma


Mantle Cell Lymphoma

Non-Hodgkin Lymphoma

Cutaneous Lymphoma

Follicular Lymphoma

Low Grade Lymphoma

MALT Lymphoma

Marginal Zone Lymphoma

Waldenström Macroglobulinemia



Education, Experience and Certifications

Undergraduate Degree
Whitworth College

Medical Degree
Stanford University School of Medicine

Brigham and Women's Hospital, Internal Medicine

Stanford University Medical Center, Internal Medicine

Board Certification
Internal Medicine, 1988; Medical Oncology 2019, American Board of Internal Medicine


Seattle Met's 2019 Top Doctors award
Dr. Maloney has been recognized as a Top Doctor in Seattle Met's annual survey multiple years in a row.

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch physicians. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your physician can decide if a study is right for you. 

Find a Clinical Trial Lead by Dr. Maloney


Many of our Fred Hutch physicians conduct ongoing research to improve standards of patient care. Their work is evaluated by other physicians and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch physician has written. 

View Dr. Maloney's Publications

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes physicians, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like registered dietitians, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders. 


Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

For the Media

The Media Relations team at Fred Hutch is available to assist members of the news media who would like to arrange interviews with providers.

Email media@fredhutch.org or call 206.667.2210