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Prlic
Martin Prlic, PhD
- Professor, Immunology and Vaccine Development Program, Vaccine and Infectious Disease Division, Fred Hutch
- Member, Immunotherapy Integrated Research Center (IIRC), Fred Hutch
- Member, Pathogen-Associated Malignancies Integrated Research Center (PAM IRC), Fred Hutch
- Affiliate Associate Professor, Department of Global Health, University of Washington
- Affiliate Associate Professor, Department of Immunology, University of Washington
- Faculty Member, Interdisciplinary Program in Pathobiology, University of Washington
- Faculty Member, Molecular & Cellular Biology Program, University of Washington & Fred Hutch
Background
Dr. Martin Prlic studies how the human immune system responds to infections, vaccines and cancer. His team primarily studies T cell and innate-like T-cell responses in mucosal tissues. His lab is particularly interested in understanding how T cells function in inflammatory environments such as infections and cancer. By defining how subsets of T cells regulate their function in health and in various disease states, Dr. Prlic aims to understand how to manipulate these cells for therapeutic use and ultimately improve human health.
Education
PhD, Microbiology, Immunology and Cancer Biology Program, University of Minnesota, 2004
MS, Genetics, University of Salzburg, 1999
Research Interests
Studying T cell, innate-like T cell and NK cell responses in context of infections, vaccines and cancer
Manipulating T cell, innate-like T cell and NK cell responses for therapeutic purposes (incl. infections, vaccines and cancer)
Mucosal immunity
Single-cell analysis approaches
Current Projects
Bystander-activation of memory T cells and subsequent effects on host immunity
Human mucosal-associated invariant T (MAIT) cells in health and disease
Mucosal immunity in response to infections, cancer and other inflammatory diseases