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Koch
Meghan Koch, PhD

Meghan Koch, PhD

  • Associate Professor, Basic Sciences Division, Fred Hutch
  • Member, Immunotherapy Integrated Research Center (IIRC), Fred Hutch
  • Member, Pathogen-Associated Malignancies Integrated Research Center (PAM IRC), Fred Hutch
206.667.3655
206.667.6526

Background

Dr. Meghan Koch studies how maternal-derived signals shape infant development, immunity and metabolism. Breastmilk transfers nutrients and specialized immune proteins, such as antibodies, to infants. These antibodies help protect infants from infection. They also influence the infant gut microbiota, the collection of microbes that colonize the intestines. The microbiota is key to health, and perturbations can have long-term effects on infant growth and immune responses later in life, including risk of allergy and asthma. Dr. Koch studies how an infant’s developing immune system learns to coexist with these microbes, and how maternal antibodies shape this process. She also examines the long-term consequences of changes in these early maternal-infant interactions.

Education

University of Washington, 2010, PhD (Immunology)

University of California, Santa Barbara, 2004, BS (Cell & Developmental Biology)

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Stories

All news
Oh, the microbes you’ll meet! Fred Hutch Cancer Center immunologist discovers a biological mechanism sprung in the first week of life that trains a mouse pup’s immune system to tolerate harmless gut bugs and new foods September 18, 2025
Lessons from mom: How to be the best immune system you can be Dr. Meghan Koch’s work in mice on how breast milk’s immune proteins shape infant immune system, long-term health could someday help human babies May 5, 2022
Studying how maternal immune factors shape infant health Immunologist Dr. Megan Koch named 2020 Pew Scholar in the Biomedical Sciences June 15, 2020