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Hsu
Li Hsu, PhD

Li Hsu, PhD

  • Professor, Biostatistics Program, Public Health Sciences Division
  • Member, Translational Data Science Integrated Research Center (TDS IRC), Fred Hutch
  • Affiliate Professor, University of Washington
206.667.2854
206.667.7004

Background

Dr. Li Hsu is a biostatistician who develops statistical methods and conducts collaborative research including observational studies of cancer and other chronic diseases with an emphasis on analysis of survival outcome, genetics and genomics data. Dr. Hsu has developed methods for absolute risk estimation and risk prediction, complex sampling designs, genome-wide association and gene-environment interaction of common and rare variants, analysis of genomic instability, and incorporation of functional data into genetic association studies. She analyzes genetic, genomic and lifestyle/environmental data in population-based and family-based studies with a focus on: genome-wide association and disease risk prediction using genetic and environmental risk factors; evaluation of risk prediction models in cohort studies; gene expression and somatic mutations in tumor tissues; and integration of multi-omics data. She is also interested in electronic health record data and evaluating genetic, biomarker and environmental risk factors with various phenotypes, or observable traits, in real-world settings.

Research Interests

Dr. Hsu is a member of the research group Fred Hutch Investigators in Novel Diagnostics for Cancer (FHIND Cancer)

Education

PhD, University of Washington, Biostatistics, 1994

MS, University of Washington, Biostatistics, 1991

BS, Nanjing University, Computer Science, 1989

Awards & Honors

2017 - American Statistical Association Fellow

2015 - Prentice Professorship, University of Washington

1991-1994 - Merck, Sharp & Dohme Research Laboratories, Predoctoral Fellowship

1991 - Donovan J. Thompson Award for outstanding student in biostatistics, University of Washington

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Looking beyond suspect genes in cancer Fred Hutch is among 10 institutions in the U.S., the U.K. and Europe collaborating to find the function of every protein-coding gene in the human genome August 21, 2025
3 new grants power colorectal cancer studies Research will focus on CRC in Alaska Native people, gene + environment interactions and how systemic racism impacts care October 18, 2023
New study of Asian, Native Hawaiian and Pacific Islander populations gets $38.7M grant Fred Hutch will act as coordinating center for large study of cardiovascular and other chronic diseases in overlooked populations September 14, 2023