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Fredricks
David N. Fredricks, MD

David N. Fredricks, MD

Infectious Disease

  • Physician, Fred Hutch
  • Professor and Associate Program Head, Infectious Disease Sciences Program, Vaccine and Infectious Disease Division, Fred Hutch
  • Professor, Clinical Research Division, Fred Hutch
  • Member, Pathogen-Associated Malignancies Integrated Research Center (PAM IRC), Fred Hutch
  • Member, Translational Data Science Integrated Research Center (TDS IRC), Fred Hutch
  • Professor, Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington School of Medicine
Fredricks Lab

About

Dr. David Fredricks is a board-certified infectious diseases physician and researcher at Fred Hutch. He focuses on infections in cancer and blood and marrow transplant patients and research on human microbiomes.

Background

Dr. Fredricks cares for patients with infectious diseases, including those with cancer and people who have received blood and marrow transplants. His clinical interests include diagnosing and treating complex bacterial and fungal infections and using advanced molecular tools to identify infections and discover new pathogens.

In addition to patient care, Dr. Fredricks studies the human microbiome — the trillions of microorganisms that live in and on the body — to understand how changes in microbial communities affect health and disease. His work has examined microbes linked to bacterial vaginosis, a common condition associated with increased risks of pelvic inflammatory disease, HIV and other sexually transmitted diseases. He also studies how microbial communities, particularly in the gut, influence outcomes for blood stem cell transplant recipients. Dr. Fredricks’ research has shown that changes in gut bacteria after antibiotic treatment may help predict the risk of graft-versus-host disease, a potentially life-threatening transplant complication.

Dr. Fredricks also leads the Microbiome Research Initiative at Fred Hutch, a collaborative effort that brings together experts from multiple disciplines to better understand how microbial communities affect human health and how this knowledge can improve patient care.

Area of Clinical Practice
Infectious diseases, allergy and immunology

Determining how changes in microbial communities impact human health

Identifying, characterizing, and culturing microbes found in the human genital tract

Associating the reproductive tract microbiome with human disease

Developing molecular diagnostic tests to detect and identify pathogens in immunocompromised hosts such as cancer patients

Studying antifungal and antibacterial therapies for cancer patients

Understanding changes in the microbiome in patients undergoing cancer therapy

Ecology of human microbial communities

Nucleic acid sequence-based methods for discovering novel pathogens

Developing diagnostic tests based on microbial nucleic acid sequences to detect human pathogens

Languages

English

Education and Experience 

Fellowship, Infectious Disease, Stanford University

Residency, Internal Medicine, University of California, San Francisco

Internship, Internal Medicine, University of California, San Francisco

MD, Case Western Reserve University

MS, Biology, Stanford University

BS, Biology, Stanford University

Board Certifications

Infectious Diseases, American Board of Internal Medicine; Internal Medicine, American Board of Internal Medicine

Clinical Trials

We make promising new treatments available to you through studies called clinical trials led by Fred Hutch physicians and researchers. Many of these trials at Fred Hutch have led to FDA-approved treatments and have improved standards of care globally. Together, you and your physician can decide if a study is right for you.

Find a Clinical Trial Led by Dr. Fredricks

Publications

Many of our Fred Hutch physicians and researchers conduct ongoing research to improve standards of patient care. Their work is evaluated by others in their field and selected for publication to the United States National Library of Medicine, the largest medical library in the world. See scientific papers this Fred Hutch physician has written.

View Dr. Fredricks' Publications

Your Care Team

At Fred Hutch, you receive care from a team of providers with extensive experience in your disease. Your team includes physicians, a patient care coordinator, a registered nurse, an advanced practice provider and others, based on your needs. You also have access to experts like registered dietitians, social workers, acupuncturists, psychiatrists and more who specialize in supporting people with cancer or blood disorders. 

Meet Other Providers

Insurance

Fred Hutch accepts most national private health insurance plans as well as Medicare. We also accept Medicaid for people from Washington, Alaska, Montana and Idaho. We are working to ensure that everyone, no matter what their financial situation, has access to the care they need.

More About Insurance

Stories

All news
Zeroing in on vaginal microbes that most increase HIV risk
Zeroing in on vaginal microbes that most increase HIV risk Signature combination of BV bacteria and immune proteins associated with highest risk could help guide prevention September 9, 2024
New bacterium named in honor of Fred Hutch
New bacterium named in honor of Fred Hutch First organism named after research center linked to bacterial vaginosis, higher HIV risk February 24, 2021
New regional collaborations will accelerate innovation in data-intensive medical science
New regional collaborations will accelerate innovation in data-intensive medical science Three research teams in Washington, Oregon and British Columbia receive pilot funding from Cascadia Data Alliance November 5, 2020

Contact Information

206.667.1935

206.667.4411