Join a Clinical Trial
Whether you are eligible for a research study depends on many things. There are specific requirements to be in research studies. These requirements are different for each clinical trial.
Cord Blood Transplant, Cyclophosphamide, Fludarabine, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Diseases
Complete Title: Optimized Cord Blood Transplantation for the Treatment of High-Risk Hematologic Malignancies in Adults and Pediatrics
Trial Phase: II
Investigator: Ann Dahlberg
This phase II trial studies how well giving an umbilical cord blood transplant together with cyclophosphamide, fludarabine, and total-body irradiation (TBI) works in treating patients with hematologic diseases. Giving chemotherapy, such as cyclophosphamide, fludarabine and thiotepa, and TBI before a donor cord blood transplant (CBT) helps stop the growth of cancer and abnormal cells and helps stop the patient`s immune system from rejecting the donor`s stem cells. When the healthy stem cells from a donor are infused into the patient they may help the patient`s bone marrow make stem cells, red blood cells, white blood cells, and platelets. Sometimes the transplanted cells from a donor can make an immune response against the body`s normal cells. Giving cyclosporine and mycophenolate mofetil after transplant may stop this from happening in patients with high-risk hematologic diseases.
Keywords:
- Blastic Plasmacytoid Dendritic Cell Neoplasm(BPDN); Leukemia, Acute Myeloid (AML); Leukemia, Chronic Lymphocytic (CLL); Myelodysplastic Syndromes (MDS); Lymphoma, Non-Hodgkin (NHL); Myelodysplastic-Myeloproliferative Diseases; Neoplasms, Complex and Mixed; Leukemia, Acute Lymphoblastic (ALL)
Disclaimer: We update this information regularly. However, what you read today may not be completely up to date.
Contact Us
If you are seeking to schedule an appointment, we are here to help. You can either call us or fill out our online appointment request form.