Physicians and scientists from Fred Hutch Cancer Center and UW Medicine are testing new treatments for chronic lymphocytic leukemia (CLL), and the closely related condition small lymphocytic lymphoma (SLL), and finding new ways to use current treatments.
Through this work, we are looking for answers to two main questions: How can we do even better at controlling these diseases? How can we make treatments less toxic and easier on patients?
Chronic Lymphocytic Leukemia Clinical Trials
Fred Hutch typically has over 750 active cancer clinical trials enrolling participants.
Clinical trials may allow some patients access to a promising new treatment, and help physicians and researchers learn more about a disease.
Why Clinical Trials Matter
Fred Hutch has been part of, and led, many clinical trials of promising therapies that later became the standard of care.
We have many clinical trials testing dozens of approaches to CLL/SLL. Some of the therapies we are studying include:
- Early intervention for people with high-risk CLL
- Novel (new) targeted therapies and new combinations that get good results, even though they only need to be taken for a limited time
- Immunotherapies, including antibody therapies, immune checkpoint inhibitors and cellular immunotherapies, like CAR T-cell therapy
- Blood and marrow transplant regimens (treatment plans)
When your care team designs your treatment plan, they will give you the choice to join clinical trials that match your situation. If you decide to join one, you will see the same physicians and nurses as you would for standard therapy.
Your care team will talk with you about if you might want to join a study and why. This can help you make the decision that is best for you.
Our CLL Researchers and Faculty
Our scientists and providers work together to diagnose and treat CLL as well as other blood disorders. The lab research and clinical research they do are essential parts of the scientific process that leads to new treatments and better care. Clinical trials can also be a way for patients to get early access to new leading-edge therapies. Our research teams are running many clinical studies for people with CLL.
See below for our researchers and faculty or view our CLL care team providers.