Leonidas Stamatatos, PhD

Leonidas Stamatatos, PhD

Affiliate Professor, Department of Global Health
University of Washington

Education

Université d’Orleans, France, BA, 1982, Biochemistry
Université de Paris XI, France, M.Sc 1983, Organic Chemistry
McGill University, Canada, Ph.D. 1988, Biochemistry
 

Research Interests

We investigate the B cell responses to infection or vaccination. We are particularly interested in understanding the activation, survival and maturation of B cell clonal lineages that produce protective antibodies against infectious agents. New immunogens and immunization regiments are developed to target these B cell lineages and are tested in vivo. We employ diverse experimental approaches, including structure-based immunogen-design, X-ray crystallography, next generation deep sequencing, and immunological, molecular and cellular techniques. Our work encompasses the entire space between pre-clinical and clinical evaluation of candidate vaccines.

Current Projects

  • Identify immunological factors associated with the development of broadly neutralizing anti-HIV-1 antibodies and pathways of viral escape
  • Immunogen-design efforts to elicit broadly neutralizing anti-HIV-1 antibodies
  • Clinical testing of HIV-1 vaccine candidates
     


Related Labs & Projects

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Leonidas Stamatatos, PhD

Contact Information

Phone
(206) 667-2995
Fax
(206) 667-7767
Email
Additional contact

Mail Stop: E5-110