Every investigator at Fred Hutch has access to shared facilities and cutting-edge technologies and expertise that can help speed the process of discovery — and that few individual labs could afford on their own. This multimillion-dollar infrastructure is also accessible to members of the Cancer Consortium, academic and industry research partners, and some other external clients. Our shared resources include core facilities that are staffed by experts who can help investigators design experiments, choose the most suitable tests and equipment, create customized tests and software tools, and analyze experimental results. In all, they offer dozens of services in addition to access to equipment and tools.
This shared resource provides custom-designed monoclonal antibodies, antigen design, immunization and screening strategies, and hybridoma cell line production and optimization.
This shared resource is staffed by bioinformatics specialists who help researchers process, explore and understand genomics data and develop new tools and techniques.
This shared resource is the largest and most comprehensive facility of its kind in Washington state and supports both fundamental and preclinical projects. It is also the only local microscopy facility that offers cryo-techniques. Our light microscopy capabilities include screening for cancer drugs, live cell assays for the development of CAR T cell–based therapies and multi-photon microscopy.
This facility is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care and complies with all U.S. Department of Agriculture, Public Health Service, Washington state and local area animal welfare regulations.
This shared resource provides a broad range of histology, histochemistry, immunochemistry and pathology services, including a wide range of special stains. The Experimental Histopathology team has extensive experience working with human tissue as well as other experimental model systems.
This shared resource offers a wide array of cell analysis and cell sorting instrumentation — from single-laser benchtop analyzers to complex multi-laser cell sorts for cell analysis and sorting — as well as expert technical staff who offer consulting on process-related matters, including experimental design, data analysis and troubleshooting.
This shared resource supports the generation of genomics-based data through DNA array, genetic analysis and high-throughput screening.
This shared resource supports studies of cellular immunity, including assays of cell populations and responses in clinical trials.
This shared resource provides support for characterizing proteins and peptides by mass spectrometry and high-performance liquid chromatography.
This shared resource provides a wide range of services, including processing of blood, urine and buccal specimens; DNA extractions and DNA fingerprinting; specimen storage options; and tissue culture of B cells.
This shared resource offers development and manufacturing expertise for novel biological molecules, as well as innovative cell-based therapies for preclinical studies and Phase 1/2 clinical testing.
Shared resources are critical to Fred Hutch’s five-year strategic plan, which calls for an increase in interdisciplinary research that cuts across divisional boundaries. To help teams access emerging technologies — a key component of the strategic plan — these centralized facilities invest in cutting-edge equipment and tools. Importantly, junior and senior faculty members have equal access. This approach offers huge benefits to groups such as our integrated research centers, which includes faculty from all five Fred Hutch scientific divisions.