Joshua A. Hill MD

Joshua A. Hill MD

Assistant Member
Clinical Research Division
Attending Physician, SCCA Infectious Disease Service
Seattle Cancer Care Alliance
Assistant Professor
University of Washington

Education

B.A., Liberal Arts Plan II Honors Program and Natural Sciences, Dean’s Scholars Program, University of Texas at Austin, 2005

M.D., University of Texas Southwestern Medical Center, Dallas, 2009

Resident, Internal Medicine Residency, Brigham and Women’s Hospital, Harvard, Boston, 2009-2012

Fellow, Harvard School of Public Health, Boston, 2013

Fellow, Division of Allergy and Infectious Diseases, University of Washington Medical Center, Seattle, 2012-2015

Clinical Expertise

I specialize in the treatment of infectious diseases in cancer patients, solid organ transplant patients, and other immunocompromised patients with a particular interest in viral infections.

Research Focus

Dr. Hill’s research focuses on the epidemiology of infections in immunocompromised hosts, with translational projects pertaining to diagnostic and treatment strategies. The focus of his studies include viral infections, such as human herpesvirus 6 (HHV-6), and infections in patients receiving immunotherapies such as CAR-T cells. Dr. Hill’s interest in this field stems from his experiences as a clinician, where he witnesses the impact of infections in vulnerable patients. Dr. Hill’s research is highly collaborative, and he works closely with oncologists, pulmonologists, pathologists, molecular virologists, and statisticians. Dr. Hill also participates clinical trials of new therapies to prevent or treat infections in immunocompromised patients.

Selected Publications

Hill JA, Li D, Hay KA, Green ML, Cherian S, Chen X, Riddell SR, Maloney DG, Boeckh M, Turtle CJ. Infectious Complications of CD19-Targeted Chimeric Antigen Receptor-Modified T Cell Immunotherapy. Blood. 2018, in press [original work]

Hill JA, Magaret A, Hall-Sedlak R, Mikhaylova A, Huang M-L, Sandmaier BM, Hansen JA, Jerome KR, Zerr DM, Boeckh M. Outcomes of Hematopoietic Cell Transplantation using Donors or Recipients with Inherited Chromosomally Integrated HHV-6. Blood. 2017, PMCID: PMC in process [original work]

Hill JA, Mayer BT, Xie H, Leisenring WM, Huang M-L, Stevens-Ayers T, Milano F, Delaney C, Sorror ML, Sandmaier BM, Nichols G, Zerr DM, Jerome KR, Schiffer JT, Boeckh M. The cumulative burden of double-stranded DNA virus detection after allogeneic HCT is associated with increased mortality. Blood. 2017, PMCID: PMC5399484 [original work]

Hill JA†
, Mayer B†, Xie H, Leisenring WM, Huang M-L, Stevens-Ayers T, Milano F, Delaney C, Jerome KR, Zerr DM, Nichols G, Boeckh M, Schiffer JT. Kinetics of Double-Stranded DNA Viremia After Allogeneic Hematopoietic Cell Transplantation. Clin Infec Dis, in press [original work] 

Greninger AL, Knudsen GM, Roychoudhury P, Hanson DJ, Sedlak RH, Xie H, Guan J, Nguyen T, Peddu V, Boeckh M, Huang M-L, Cook L, Depledge DP, Zerr DM, Koelle DM, Gantt S, Yoshikawa T, Caserta M, Hill JA, Jerome KJ. Genomic and proteomic analysis of Human herpesvirus 6 reveals distinct clustering of acute versus inherited forms and reannotation of reference strain. BMC Genomics. 2018; 19(1):204 PMCID: PMC5859498 [original work]

Hill JA†, Sahoo F†, Xie H, Leisenring W, Yi J, Goyal S, Kimball LE, Lee I, Seo S, Davis C, Pergam S, Flowers M, Liaw K-L, Holmberg L, Boeckh M. Herpes Zoster in Autologous Hematopoietic Cell Transplant Recipients in the Era of Acyclovir or Valacyclovir Prophylaxis and Novel Treatment and Maintenance Therapies. BBMT. 2017, PMCID in process [original work]

Hill JA†, Lopez Roa P†, Kirby KA, Leisenring WM, Huang M-L, Santo TK, Jerome KM, Boeckh M, Limaye AP. Co-Reactivation of HHV-6 and CMV is Associated with Worse Clinical Outcome in Critically Ill Adults. Crit Care Med. 2015 Jul; 43(7):1415-22. PMCID: PMC4470856. †Lopez Roa is listed first on the publication.

Hill JA, Koo S, Guzman Suarez BB, Ho VT, Cutler C, Koreth J, Armand P, Alyea III EP, Baden LR, Antin JH, Soiffer RJ, Marty FM. Cord-blood hematopoietic stem cell transplant confers an increased risk for human herpesvirus-6-associated acute limbic encephalitis: a cohort analysisBiol Blood Marrow Transplant 18, 1638–48 (2012). PMCID: PMC3816521 [original work]

Awards and Honors

George Santos Award for best clinical science article by a new investigator, American Society for Blood and Marrow Transplantation, 2012
Robert A. Good New Investigator Award, American Society for Blood and Marrow Transplantation, 2014
Joel Meyers Infectious Diseases Scholar, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, 2014
NIH Clinical Loan Repayment Program Award, 2015
NIH/NIAID K23 Career Development Award, 2015
Caroline B. Hall Young Investigator Award, 9th International HHV-6 & 7 Conference, 2015
Amy Strelzer Manasevit Research Program Scholar Award, NMDP/ASBMT, 2018



Joshua Hill, MD

Contact Information

Phone
(206) 667-6504
Fax
(206) 667-4411
Email
Additional contact

Mail Stop: E4-100

Website