The Cryo-EM core is Fred Hutch’s newest shared resource. We aim to bring a new structural determination technique to support users seeking to solve difficult molecular structures at an ultrafine scale. Recent advances in cryo-EM technology and software algorithms have made it a compelling structural biology method for flexible proteins that resist visualization by other techniques.
We offer training in all steps of the cryo-EM process, from sample preparation to image processing. All users will be supported by experienced staff members and will be granted 24/7 access to the microscopes and sample preparation instruments after they have satisfied training requirements. Our instruments, training and services are available to both internal and external users.