Rigor, Reproducibility and Transparency Training Program

The Rigor, Reproducibility, and Transparency (RRT) Seminar Series is a series in collaboration with the University of Washington presented by faculty from each of the several ongoing training grants at Fred Hutch and UW. The series is in response to recently mandated RRT training by the NIH for trainees on training grants, F awards, and K awards. Lectures focus on a detailed discussion of common or emerging methodologies with the aim of describing strengths, limitations, and pitfalls so those employing or interpreting the data gain a realistic sense of what can and cannot be learned. Trainees are encouraged to attend lectures outside of their field of expertise as it is likely that they will encouter data from these methods, and understanding how they work and what their limitations are is crutial, so the talks are designed to be accessible to a broad biomedical audience.

All trainees on training grants should check with their training grant director for required attendance, and F & K awardees are strongly encouraged to participate. 

The RRT seminar series will be held every 2 months. There are 2 ways to receive credit for participation:

1. Attend the seminar live

2. Watch the video recording of the seminar within 30 days

After attending live or viewing the recording, attendees will fill out a survey and state 3 things learned.

Suzanne Hoppins, PhD

May 3, 2022, 2 PM - The reconstitution of mitochondrial fusion

Andrew Oberst, PhD

March 8, 2022, 2 PM - Effective use of mouse models for biological research

Larry Zweifel, PhD

January 18, 2022, 2 PM - Rigor and reproducibility in targeting gene function using viral-mediated CRISPR/Cas9 mutagenesis

Alice Berger, PhD

October 12, 2021, 2 PM - On-Target Discovery: Rigor and reproducibility in genetic screens

Stefan Stoll, PhD

September 28, 2021, 2 PM - Protein Conformational Changes: Using Bayesian Inference to Quantify Uncertainty and Make Robust Conclusions

Joshua Vaughan, PhD

May 4, 2021, 2 PM - Rigor and Reproducibility in Optical Microscopy

Miklos Guttman, PhD

March 23, 2021, 2 PM - Overcoming irreproducibility in hydrogen/deuterium exchange studies: Establishing rigor and reproducibility in a technique approaching its adolescence

Ruth Etzioni, PhD

January 12, 2021, 2 PM - Getting the numbers right - common statistical misses in the news and in the lab

Lucas Sullivan, PhD

November 17, 2020, 2 PM - Rigor and Reproducibility in Metabolomics

Chetan Seshadri, MD

September 15, 2020, 10 AM - Rigor and Reproducibility in Flow Cytometry

Jesse Bloom, PhD

July 16, 2020, 2 PM - Studying the impacts of mutations to SARS-CoV-2

Andrea Wills, PhD

May 14, 2020, 1 PM - Querying chromatin accessibility in complex tissues with ATAC-Seq