Training Program

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Our fellowship program is dedicated to advancing the art and science of medicine through a rich and diverse educational experience at top-flight academic medical centers — Fred Hutchinson Cancer Research Center and University of Washington. The program is a collaborative effort with the Seattle Cancer Care Alliance (SCCA), Bloodworks Northwest (BWNW), Harborview Medical Center (HMC) and VA Puget Sound Health Care System (VAPSHCS).

Our fellowship program offers trainees a dynamic clinical exposure across many sites that result in an unparalleled experience. Not only do our fellows spend time immersed in the tertiary care that occurs at the University of Washington Medical Center and Seattle Cancer Care Alliance, but have added benefit of serving the underserved at Harborview Medical Center, and caring for the veterans at the Seattle Branch of the Puget Sound VA. Furthermore, fellows are exposed to the cutting edge of transfusion medicine and immunohematology at the world-class Bloodworks Northwest.

Our interdisciplinary research program focuses on both clinical and basic research in hematology and cancer biology as well as therapeutic intervention.

Clinical Focus

physician with patient

Our program is committed to the conduct of clinical research to identify new approaches to therapy for patients with malignant disorders and benign hematologic disorders. Clinical research investigations are ongoing in areas of bone marrow transplantation, general oncology, hematology, chemotherapy pharmacokinetic and pharmacogenetic interactions, cancer epidemiology, late effects of therapy, quality of life, palliative care. New agents in cancer treatment are being investigated through investigator-initiated clinical trials, pharmaceutical company trials and international and national consortia trials.

The University of Washington and Fred Hutch-based faculty are national leaders in areas of novel approaches across the many areas of hematology and oncology. The University of Washington and Fred Hutch serves as one of the lead centers, as well as the statistical center, for the SouthwestOncology Group (SWOG) and an active participant in the Blood and Marrow Transplant Clinical Trials Network (BMT-CTN).

Seattle Cancer Care Alliance Clinical Trials
University of Washington-based faculty who have clinics at the SCCA are active participants in SCCA and Southwest Oncology Group (SWOG) protocols in leukemia, lymphoma, lung, breast, GU, brain tumor, and melanoma. Clinical trials are underway using dose dense therapy for breast cancer, high dose therapy for non-Hodgkin’s Lymphoma with marrow-ablative or non-marrow-ablative antibody approaches. As the largest sarcoma and melanoma programs in the Pacific Northwest, clinical investigation is particularly active in these areas. In particular, the use of biologic-response modifiers with IL-2, in renal cell cancer and melanoma is pursued on the inpatient service.

Continued expansion of the clinical research protocols is anticipated as programs are integrated in the SCCA. Find more information about clinical trials at SCCA and Fred Hutch.

Training Sites

Harborview Medical Center

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photos of Manoj Menon, M.D., M.P.H.

Manoj Menon, M.D., M.P.H.

Training Site Director

Section Head, Hematology, Harborview Medical Center
Assistant Member, Vaccine and Infectious Disease Division, Fred Hutch
Assistant Member, Clinical Research Division, Fred Hutch
Assistant Professor, Division of Hematology, Department of Medicine, UW School of Medicine

Harborview Medical Center (HMC) is a 413-bed county hospital that serves as the Level I trauma center for a several state area and also provides primary care to indigent patients and patients with HIV-related illnesses. The fellow sees hematology and oncology patients as a consultant on the inpatient ward services and in clinic. There is no inpatient hematology/oncology service, so patients are admitted to a general medical service where the team acts as consultants. There are usually 0-5 new consults per day, and the team generally follows approximately 10 patients. Patients seen on the consult service may also be seen in follow up in the Hematology/Oncology Clinic.

Bloodworks Northwest

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photo of Theresa Nester

Theresa Nester

Training Site Director | Transfusion Medicine

Bloodworks Northwest provides instruction in the theory and practical application of transfusion medicine, immunohematology and hemostasis/thrombosis toward developing consultative and primary management skills in these subdisciplines of hematology. Located in Seattle, the BWNW is the central transfusion service for all of King County (the densest county in the state of Washington). The BWNW labs provide reference services for testing and provide blood collection and distribution services, including apheresis procedures and transfusion consultation.

Training is provided in donor collection and blood processing, crossmatch and antibody identification, HLA and platelet immunology, donor testing and coagulation. Fellows have the opportunity to provide consultations to referring physicians, particularly in cases involving the management of bleeding, transfusion reactions and antibody-related clinical issues. On Wednesday afternoons fellows attend a BWNW hemophilia clinic.

Seattle Cancer Care Alliance

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photo of Rachel Yung, M.D.

Rachel Yung, M.D.

Training Site Director | Solid Tumor Oncology

Assistant Professor, Division of Medical Oncology, University of Washington
Assistant Member, Clinical Research Division, Fred Hutch

Fellows see a wide variety of oncology patients at the SCCA. Fellows attend multidisciplinary clinics in breast cancer and melanoma tumor clinics where patients are evaluated in conjunction with medical radiation and surgical oncologists. Fellows also participate in general medical oncology clinics where patients are evaluated for a variety of malignancies including GI, GU, lung, gynecologic, and hematologic malignancies.

Under the guidance of an attending physician, the fellow may evaluate from two to four new patients per day, order appropriate staging and diagnostic studies, perform bone marrow biopsies and aspirates, and formulate a plan of treatment based on history, physical, and test results. The fellow will evaluate patients for eligibility on clinical research protocols. Fellows will provide an explanation of the study and alternative treatment, enrollment criteria, and coordination of the treatment program. Cases requiring interdisciplinary management may be seen in one of several specialty clinics.

photo of Michael Linenberger, M.D., F.A.C.P.

Michael Linenberger, M.D., F.A.C.P.

Training Site Director | Hematology

Medical Director, Apheresis and Cellular Therapy, SCCA
Associate Member, Clinical Research Division, Fred Hutch
Professor, Division of Hematology, Department of Medicine, UWSOM

Fellows learn about the presentation, pathophysiology, clinical manifestations, diagnostic approaches and treatment of a wide variety of benign and malignant hematologic disorders. Fellows attend multidisciplinary clinics in hematology and hematologic malignancies at SCCA. Fellows participate in a variety of ambulatory care clinics at the SCCA including lymphoma, MDS, myeloma and hematology.

This rotation also provides an opportunity to observe in the Apheresis Unit and Cellular Therapy Lab to gain an understanding of the technical and clinical aspects of peripheral blood stem cell mobilization and collection, processing and cryopreservation. Fellows also participate in consultations for patients who may be candidates for blood and marrow transplantation (BMT), as well as see long-term BMT follow-up patients.

photo of Marco Mielcarek, M.D., Ph.D.

Marco Mielcarek, M.D., Ph.D.

Training Site Director | Blood & Marrow Transplantation (Ambulatory)

Medical Director, Adult Blood and Marrow Transplant Program, SCCA
Associate Member, Clinical Research Division, Fred Hutch
Associate Professor, Division of Medical Oncology, Department of Medicine, UWSOM

The SCCA BMT ambulatory care rotation pairs fellows with foremost experts in the BMT field. The goal of this rotation is to learn the theory, indications, treatment approaches, complications and outcomes of autologous and allogeneic bone and marrow transplantation and to develop confidence and clinical expertise in the care and management of transplant recipients. BMT patients are followed pre- and post-transplant for a period of approximately 100 days, after which they are referred back to their referring physician. Fellows see patients admitted for stem cell infusion in preparation for non-myeloablative transplants and unrelated “mini” transplants.

Fellows have the opportunity to conduct a patient care conference of his/her choosing:

  • arrival (a summary of the major issues to be addressed during pre-transplant evaluation);
  • data review (a summary of the pre-transplant evaluation results and upcoming transplant treatment plans, goals, risks and potential adverse events); or
  • discharge (a summary of post-transplant events and recommendations for further therapy after discharge from the BMT service).

University of Washington Medical Center

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photo of Paul Hendrie, M.D., Ph.D.

Paul Hendrie, M.D., Ph.D.

Training Site Director | Leukemia Service

Clinical Associate Professor, Division of Hematology, Department of Medicine, UWSOM
Associate Medical Director, Inpatient Hematology/Oncology Service, SCCA at UWMC

The fellow works as an active consultant on this inpatient rotation and works directly with the residents, nursing staff, pharmacists, social workers, and the attending physician to assure appropriate workup and care of patients. The fellow supervises the resident who is responsible for primary medical management. The inpatient unit includes patients with new diagnoses of leukemia, lymphoma, aplastic anemia, sickle cell disease, and many solid tumor cancers including renal cell, colorectal, breast and melanoma. The UWMC is a referral center for the five WWAMI states (Washington, Wyoming, Alaska, Montana, Idaho) as well as a local primary care site.

photo of Sioban B. Keel, M.D.

Sioban B. Keel, M.D.

Training Site Director | Hematology Consult / Laboratory Medicine

Associate Professor, Division of Hematology, Department of Medicine, UWSOM

This rotation provides the opportunity to learn about the work-up, laboratory assessment and treatment of a wide variety of hematologic consultative issues. The focus is benign hematology. Hematology consults often involve evaluation of adenopathy, splenomegaly, and cytopenias, and the management of complex bleeding abnormalities or thrombotic complications, especially in surgical and obstetrical settings.

The UWMC is a referral center for the five WWAMI states (Washington, Wyoming, Alaska, Montana, Idaho), and thus, is an active site for both basic medical care and for tertiary referral issues, such as liver transplantation, complex surgery, and high-risk obstetrics. The use of flow cytometry and immunocytochemistry methods are important focuses of this rotation.

photo of Marco Mielcarek, M.D., Ph.D.

Marco Mielcarek, M.D., Ph.D.

Training Site Director | UWMC Blood and Marrow Transplantation Inpatient Unit

Medical Director, Adult Blood and Marrow Transplant Program, SCCA
Associate Member, Clinical Research Division, Fred Hutch
Associate Professor, Division of Medical Oncology, Department of Medicine, UWSOM

The BMT inpatient rotation at UWMC pairs fellows with foremost experts in the BMT field. The goal of this rotation is to learn the theory, indications, treatment approaches, complications and outcomes of autologous and allogeneic stem cell transplantation and to develop confidence and clinical expertise in the care and management of transplant recipients. Fellows provide primary care of patients with the assistance of the attending physician, nursing, pharmacy, social services, transition team, and the outpatient clinic providers. The fellow is responsible for the intake, daily management, diagnostic and therapeutic decision-making, documentation (paper and electronic), and coordination of discharges. Supportive care includes platelet and granulocyte transfusions, reverse-isolation techniques, Hickman catheters, nutrition research, plasma exchanges, ex vivo immunoabsorption, infection prevention and treatment in granulocytopenic and immunosuppressed patients. Basic principles of intensive chemoradiotherapy are emphasized.

photo of Monica Pagano

Monica Pagano

Training Site Director | Transfusion Medicine

Veterans Affairs Puget Sound Health Care System

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photo of Jonathan Grim, M.D., Ph.D.

Jon Grim, M.D., Ph.D.

Training Site Director | VAPS Solid Tumor Oncology

Attending Physician, VA Puget Sound Health Care System
Associate Member, Clinical Research Division, Fred Hutch
Assistant Professor, Division of Medical Oncology, University of Washington

The primary goal of this rotation is to develop effective consultation skills and enhance medical knowledge about a wide variety of oncologic disorders including lung, genitourinary/prostate, and head and neck cancer. The cancer program is certified as a Teaching Hospital Cancer Program by the Commission on Cancer and as a Comprehensive Cancer Center by the VA. The VA has facilities for all aspects of cancer therapy including radiation therapy, interstitial therapy, subspecialty surgery (orthopedics, neurosurgery, urology, otolaryngology, thoracic surgery, and cardiac surgery) and interventional radiology.

photo of Robert Richard, M.D., Ph.D.

Robert Richard, M.D., Ph.D.

Training Site Director | VAPS Hematology Consult

Director, Hematology, VA Puget Sound Health Care System
Associate Professor, Division of Hematology, Department of Medicine, UWSOM

Fellows develop effective consultation skills and enhance medical knowledge by seeing a wide variety of benign and malignant hematologic disorders. The Hematology Service receives on average 8 to 10 consults per week, primarily from the inpatient VAPS services but also from VA facilities throughout the state and Alaska. Most of the outside consult requests can be handled as electronic non-visit consults. The Hematology Consult Service fellow sees all inpatient consults and reviews electronic outpatient consults to determine acuity of the question, respond to the consult, and review their response with the attending physician. The problems encountered as electronic consults are primarily benign hematologic issues such as anemia, cytopenias, and thrombo-embolic disorders.

tech at laboratory bench

Research Focus

Primary laboratory research focuses are:

  • transplantation biology 
  • immunology and adoptive immunotherapy
  • genetic engineering and gene therapy 
  • solid tumor biology
  • experimental chemotherapy and mechanisms of drug resistance
  • the nature and control of normal and malignant hematopoiesis

Ongoing basic research focuses are:

  • developmental aspects of hematopoiesis, including hematopoietic stem cell expansion, immune reconstitution following hematopoietic stem cell transplant and molecular analyses of normal and malignant hematopoiesis
  • molecular analyses of bone marrow failure syndromes
  • developmental immunology and adoptive immunologic approaches to cancer therapy
  • neuro-oncology and solid tumor research including growth and differentiation of normal and malignant tissues and mechanisms of chemoresistance
  • additional interdisciplinary research involving nanotechnology and molecular imaging for neurologic disease and solid tumor diagnosis, treatment, and response evaluation

Research Mentors are Available at all Our Affiliated Institutions:

Contact Us

Claire Moore

Program Coordinator

Hematology-Oncology Fellowship Program
University of Washington/Fred Hutchinson Cancer Research Center
1100 Fairview Ave N – D5-100
Seattle, WA 98109-1024