Etiology Research

Etiology

Our etiologic research focuses on understanding the causes of cancer and other related diseases. These studies examine exposures such as nutrition, obesity, alcohol consumption, medication use, air pollution, genetics, and many others for their relationship with the risk of developing cancer. Our scientists are working to generate the knowledge and evidence needed for the development of new risk prediction and prevention strategies.

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Acute Effects of Exercise on Breast Cancer Biomarkers (ACE) Study

Public Health Sciences, Epidemiology

The Acute Effects of Exercise on Breast Cancer Biomarkers (ACE Study) is enrolling women to test the effect of moderate intensity exercise on cancer risk factors such as biomarkers in healthy women. Knowing if exercise significantly alters these biomarkers, could help support guidelines for daily exercise for breast cancer prevention and could indicate that exercise even without weight loss is beneficial.

Contact: Jude Warner, acestudy@fredhutch.org

Advanced Colorectal Cancer of Serrated Subtype (ACCESS) Study

Public Health Sciences, Cancer Prevention

Researchers are studying a subtype of colorectal cancer (CRC) that develops via the serrated pathway with a goal of determining future prevention strategies and advancing treatment for CRC.

Funding Agency: National Institutes of Health

Contact: Rachel Malen, rmalen@fredhutch.org

Advancing our Understanding of the Etiologies and Mutational Landscapes of Basal-like, Luminal A, and Luminal B Breast Cancer

Public Health Sciences, Epidemiology

Addressing research gaps in the molecular subtypes of breast cancer, we are taking a multidisciplinary approach to study the epidemiology and mutational landscapes of basal-like, luminal A, and luminal B tumors.

Funding Agency: DOD

Contact: Sarah Taylor, sataylor@fredhutch.org

Ancillary Cost-Effectiveness Analysis

Public Health Sciences, Cancer Prevention

Researchers are determining the cost-effectiveness of cord blood vs. haplo matched relatives using clinical information from the Bone Marrow Transplant (BMT) Clinical Trials Network (CTN) and insurance claims data.

Funding Agency: National Institutes of Health

Contact: Jordan Steelquist, jsteelq@fredhutch.org

Bacterial Correlates of Colorectal Cancer Subtypes and Survival

Public Health Sciences, Epidemiology

Scientists identify differences in the bacterial community in tumors for patients with etiologically-distinct subgroups of colorectal cancer, and how those differences relate to survival.

Funding Agency: National Cancer Institute

Contact: Amanda Phipps, aphipps@fredhutch.org

Breast Cancer Initiative 2.5

Public Health Sciences, Epidemiology

Breast Cancer Initiative 2.5 is uniting the global breast cancer community behind a common goal to make breast health a global priority and reduce disparities in breast cancer outcomes for 2.5 million women by 2025.

Breast Health Global Initiative (BHGI)

Public Health Sciences, Epidemiology

The Breast Health Global Initiative is striving to improve breast health outcomes and access to breast cancer screening, detection and treatment for women in low- and middle-income countries.

Contact: Marisa Hartman, 206.667.3538

Breast, Colorectal and Ovary Cancer Clinical Validation Center

Public Health Sciences, Epidemiology

After identifying early detection biomarkers for each of these cancers, we are conducting phase 2 and phase 3 validation studies directed towards clearly defined clinical applications.

Funding Agency: National Cancer Institute

Contact: Chris Li, cili@fredhutch.org

Cancel Save & Close Menopause Strategies: Finding Lasting Answers for Symptoms and Health (MsFLASH)

Public Health Sciences, Cancer Prevention

The MsFLASH network conducts clinical trials aimed at finding promising treatments for the most common symptoms of menopause.

Cancer Epidemiology Research Cooperative (CERC)

Public Health Sciences, Epidemiology

The Cancer Epidemiology Research Cooperative (CERC) conducts research to improve knowledge about the causes of cancer and its impact on the lives of those affected, in order to reduce cancer occurrence and suffering and to improve survival.

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Other Epidemiology Areas of Research