The Safety and Efficacy of Alpha-1 Antitrypsin (AAT) for the Prevention of Graft-Versus-host Disease (GVHD) in Patients Receiving Hematopoietic Cell Transplant (MODULAATE)

Complete Title: A Phase 2/3, Multicenter, Randomized, Double-blind, Placebo-controlled, Study to Evaluate the Safety and Efficacy of Alpha-1 Antitrypsin for the Prevention of Graft-versus-Host Disease in Patients Receiving Hematopoietic Cell Transplant (MODULAATE Study)
Trial Phase: II/III
Investigator: Masumi Ueda Oshima

This study is a Phase 2/3 prospective, double-blind, randomized, multi-center, placebo-controlled study for prevention of acute GVHD (aGVHD) in subjects undergoing an allogeneic hematopoietic cell transplant (HCT).

Keywords:
  • Graft Versus Host Disease (GVHD)
  • Immune System Diseases
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Adult
II/III
Masumi Ueda Oshima
RG1004024
NCT03805789
A Phase 2/3, Multicenter, Randomized, Double-blind, Placebo-controlled, Study to Evaluate the Safety and Efficacy of Alpha-1 Antitrypsin for the Prevention of Graft-versus-Host Disease in Patients Receiving Hematopoietic Cell Transplant (MODULAATE Study)
Graft Versus Host Disease (GVHD)
Immune System Diseases