The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a p53 Y220C Mutation

Complete Title: A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation
Trial Phase: I/II
Investigator: John Thompson

This study will assess the safety and tolerability of multiple dose levels of PC14586 in participants with advanced solid tumors containing a p53 Y220C mutation.

Keywords:
  • Solid Tumors
  • Neoplasms, Malignant
  • Metastatic Solid Tumors
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Adult
Pediatric
I/II
John Thompson
RG1121176
NCT04585750
A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation
Solid Tumors
Neoplasms, Malignant
Metastatic Solid Tumors