Study of RP1 Monotherapy and RP1 in Combination With Nivolumab (IGNYTE)

Complete Title: An Open-label,multicenter,Phase 1/2 study of RP1 as a single agent and in combination with PD1 blockade in patients with solid tumors.
Trial Phase: II
Investigator: Evan Hall

RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.

Keywords:
  • Melanoma
  • Skin Cancer
  • Lung Carcinoma, Non-Small-Cell (NSCLC)
  • Lymphoma, T-Cell, Cutaneous
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Adult
II
Evan Hall
RG1123074
NCT03767348
An Open-label,multicenter,Phase 1/2 study of RP1 as a single agent and in combination with PD1 blockade in patients with solid tumors.
Melanoma
Skin Cancer
Lung Carcinoma, Non-Small-Cell (NSCLC)
Lymphoma, T-Cell, Cutaneous