Study of MRTX1133 in Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation

Complete Title: A Phase 1/2 Multiple Expansion Cohort Trial of MRTX1133 in Patients with Advanced Solid Tumors Harboring a KRAS G12D Mutation
Trial Phase: I/II
Investigator: Gabriela Chiorean

This is a Phase 1/2, open-label, multicenter, study evaluating the safety, tolerability, PK, PD, and anti-tumor activity of MRTX1133 in patients with advanced solid tumor malignancy harboring a KRAS G12D mutation.

Keywords:
  • Pancreatic Cancer
  • Solid Tumors
  • Lung Carcinoma, Non-Small-Cell (NSCLC)
  • Colorectal Neoplasms
  • Advanced Solid Tumors
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Adult
I/II
Gabriela Chiorean
RG1123417
NCT05737706
A Phase 1/2 Multiple Expansion Cohort Trial of MRTX1133 in Patients with Advanced Solid Tumors Harboring a KRAS G12D Mutation
Pancreatic Cancer
Solid Tumors
Lung Carcinoma, Non-Small-Cell (NSCLC)
Colorectal Neoplasms
Advanced Solid Tumors